<?xml version="1.0" encoding="UTF-8"?>

<!--XBRL Document Created with the Workiva Platform-->
<!--Copyright 2026 Workiva-->
<!--r:019e219f-7594-78f1-86da-5d4ac039bf2b,g:41ecf867-ec9f-4605-8922-29f40f545d82-->
<link:linkbase xmlns:link="http://www.xbrl.org/2003/linkbase" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.xbrl.org/2003/linkbase http://www.xbrl.org/2003/xbrl-linkbase-2003-12-31.xsd">
  <link:arcroleRef arcroleURI="https://xbrl.org/2023/arcrole/summation-item" xlink:type="simple" xlink:href="https://www.xbrl.org/2023/calculation-1.1.xsd#summation-item"/>
  <link:roleRef roleURI="http://www.cleanharbors.com/role/CONSOLIDATEDBALANCESHEETS" xlink:type="simple" xlink:href="clh-20260630.xsd#CONSOLIDATEDBALANCESHEETS"/>
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/CONSOLIDATEDBALANCESHEETS" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_clh_AssetsNoncurrentExcludingPropertyPlantAndEquipment_019e219f-7715-7bcd-87a5-82f059698c6d" xlink:href="clh-20260630.xsd#clh_AssetsNoncurrentExcludingPropertyPlantAndEquipment"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingLeaseRightOfUseAsset_019e219f-7715-78cf-9ab2-2cbe6209deb0" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_OperatingLeaseRightOfUseAsset"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_clh_AssetsNoncurrentExcludingPropertyPlantAndEquipment_019e219f-7715-7bcd-87a5-82f059698c6d" xlink:to="loc_us-gaap_OperatingLeaseRightOfUseAsset_019e219f-7715-78cf-9ab2-2cbe6209deb0" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_Goodwill_019e219f-7715-7cd7-a21c-089622139c35" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_Goodwill"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_clh_AssetsNoncurrentExcludingPropertyPlantAndEquipment_019e219f-7715-7bcd-87a5-82f059698c6d" xlink:to="loc_us-gaap_Goodwill_019e219f-7715-7cd7-a21c-089622139c35" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IntangibleAssetsNetExcludingGoodwill_019e219f-7715-77ff-9223-3151d225b7f0" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_IntangibleAssetsNetExcludingGoodwill"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_clh_AssetsNoncurrentExcludingPropertyPlantAndEquipment_019e219f-7715-7bcd-87a5-82f059698c6d" xlink:to="loc_us-gaap_IntangibleAssetsNetExcludingGoodwill_019e219f-7715-77ff-9223-3151d225b7f0" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherAssetsNoncurrent_019e219f-7715-7357-a822-d5df506a693f" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_OtherAssetsNoncurrent"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_clh_AssetsNoncurrentExcludingPropertyPlantAndEquipment_019e219f-7715-7bcd-87a5-82f059698c6d" xlink:to="loc_us-gaap_OtherAssetsNoncurrent_019e219f-7715-7357-a822-d5df506a693f" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LiabilitiesNoncurrent_019e219f-7715-739d-82a0-88e4218560ca" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_LiabilitiesNoncurrent"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingLeaseLiabilityNoncurrent_019e219f-7715-7028-8c64-084d5986044f" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_OperatingLeaseLiabilityNoncurrent"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesNoncurrent_019e219f-7715-739d-82a0-88e4218560ca" xlink:to="loc_us-gaap_OperatingLeaseLiabilityNoncurrent_019e219f-7715-7028-8c64-084d5986044f" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccruedEnvironmentalLossContingenciesNoncurrent_019e219f-7715-72cb-bdad-d504b0d31b85" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_AccruedEnvironmentalLossContingenciesNoncurrent"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesNoncurrent_019e219f-7715-739d-82a0-88e4218560ca" xlink:to="loc_us-gaap_AccruedEnvironmentalLossContingenciesNoncurrent_019e219f-7715-72cb-bdad-d504b0d31b85" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherLiabilitiesNoncurrent_019e219f-7715-7d84-9b23-d32e26a3edca" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_OtherLiabilitiesNoncurrent"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesNoncurrent_019e219f-7715-739d-82a0-88e4218560ca" xlink:to="loc_us-gaap_OtherLiabilitiesNoncurrent_019e219f-7715-7d84-9b23-d32e26a3edca" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredIncomeTaxLiabilitiesNet_019e219f-7715-742c-885a-cab15c80ef3a" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DeferredIncomeTaxLiabilitiesNet"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesNoncurrent_019e219f-7715-739d-82a0-88e4218560ca" xlink:to="loc_us-gaap_DeferredIncomeTaxLiabilitiesNet_019e219f-7715-742c-885a-cab15c80ef3a" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccruedCappingClosurePostClosureAndEnvironmentalCostsNoncurrent_019e219f-7715-7bd8-8763-f059f6aed3ee" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_AccruedCappingClosurePostClosureAndEnvironmentalCostsNoncurrent"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesNoncurrent_019e219f-7715-739d-82a0-88e4218560ca" xlink:to="loc_us-gaap_AccruedCappingClosurePostClosureAndEnvironmentalCostsNoncurrent_019e219f-7715-7bd8-8763-f059f6aed3ee" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongTermDebtNoncurrent_019e219f-7715-7a20-b91d-88522a19de84" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_LongTermDebtNoncurrent"/>
    <link:calculationArc order="6" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesNoncurrent_019e219f-7715-739d-82a0-88e4218560ca" xlink:to="loc_us-gaap_LongTermDebtNoncurrent_019e219f-7715-7a20-b91d-88522a19de84" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AssetsCurrent_019e219f-7715-76cd-93ac-23928c544674" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_AssetsCurrent"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountsReceivableNetCurrent_019e219f-7715-7733-8482-44f2a1a2a495" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_AccountsReceivableNetCurrent"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_AssetsCurrent_019e219f-7715-76cd-93ac-23928c544674" xlink:to="loc_us-gaap_AccountsReceivableNetCurrent_019e219f-7715-7733-8482-44f2a1a2a495" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InventoryNet_019e219f-7715-73de-8c2f-ab5120a43f27" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_InventoryNet"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_AssetsCurrent_019e219f-7715-76cd-93ac-23928c544674" xlink:to="loc_us-gaap_InventoryNet_019e219f-7715-73de-8c2f-ab5120a43f27" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_MarketableSecuritiesCurrent_019e219f-7715-7358-825f-3edd1940282d" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_MarketableSecuritiesCurrent"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_AssetsCurrent_019e219f-7715-76cd-93ac-23928c544674" xlink:to="loc_us-gaap_MarketableSecuritiesCurrent_019e219f-7715-7358-825f-3edd1940282d" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_019e219f-7715-7d2e-9fa5-55d49fb099ff" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_AssetsCurrent_019e219f-7715-76cd-93ac-23928c544674" xlink:to="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_019e219f-7715-7d2e-9fa5-55d49fb099ff" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_UnbilledReceivablesCurrent_019e219f-7715-754f-acf8-269ec094b888" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_UnbilledReceivablesCurrent"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_AssetsCurrent_019e219f-7715-76cd-93ac-23928c544674" xlink:to="loc_us-gaap_UnbilledReceivablesCurrent_019e219f-7715-754f-acf8-269ec094b888" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PrepaidExpenseAndOtherAssetsCurrent_019e219f-7715-7ab6-9839-2e324cbf5e2e" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_PrepaidExpenseAndOtherAssetsCurrent"/>
    <link:calculationArc order="6" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_AssetsCurrent_019e219f-7715-76cd-93ac-23928c544674" xlink:to="loc_us-gaap_PrepaidExpenseAndOtherAssetsCurrent_019e219f-7715-7ab6-9839-2e324cbf5e2e" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LiabilitiesCurrent_019e219f-7715-7164-b146-a2388484ac6b" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_LiabilitiesCurrent"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongTermDebtCurrent_019e219f-7715-7b03-8e98-7f9ea2f45423" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_LongTermDebtCurrent"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesCurrent_019e219f-7715-7164-b146-a2388484ac6b" xlink:to="loc_us-gaap_LongTermDebtCurrent_019e219f-7715-7b03-8e98-7f9ea2f45423" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountsPayableCurrent_019e219f-7715-73fa-baed-b4b10bcff843" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_AccountsPayableCurrent"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesCurrent_019e219f-7715-7164-b146-a2388484ac6b" xlink:to="loc_us-gaap_AccountsPayableCurrent_019e219f-7715-73fa-baed-b4b10bcff843" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccruedLiabilitiesCurrent_019e219f-7715-74f0-9db1-ffde2f187400" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_AccruedLiabilitiesCurrent"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesCurrent_019e219f-7715-7164-b146-a2388484ac6b" xlink:to="loc_us-gaap_AccruedLiabilitiesCurrent_019e219f-7715-74f0-9db1-ffde2f187400" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_clh_AccruedCappingClosurePostClosureAndRemedialLiabilitiesCurrent_019e219f-7715-7e98-974b-9d7c94ccbfa3" xlink:href="clh-20260630.xsd#clh_AccruedCappingClosurePostClosureAndRemedialLiabilitiesCurrent"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesCurrent_019e219f-7715-7164-b146-a2388484ac6b" xlink:to="loc_clh_AccruedCappingClosurePostClosureAndRemedialLiabilitiesCurrent_019e219f-7715-7e98-974b-9d7c94ccbfa3" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ContractWithCustomerLiabilityCurrent_019e219f-7715-7ee1-8f8a-ffb2916d7624" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ContractWithCustomerLiabilityCurrent"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesCurrent_019e219f-7715-7164-b146-a2388484ac6b" xlink:to="loc_us-gaap_ContractWithCustomerLiabilityCurrent_019e219f-7715-7ee1-8f8a-ffb2916d7624" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingLeaseLiabilityCurrent_019e219f-7715-7fb9-9d1f-390e61ee93f5" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_OperatingLeaseLiabilityCurrent"/>
    <link:calculationArc order="6" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesCurrent_019e219f-7715-7164-b146-a2388484ac6b" xlink:to="loc_us-gaap_OperatingLeaseLiabilityCurrent_019e219f-7715-7fb9-9d1f-390e61ee93f5" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_Assets_019e219f-7715-7e8a-b48c-60b57abe7811" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_Assets"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AssetsCurrent_019e219f-7715-7d78-8cda-b5c80824cdea" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_AssetsCurrent"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_Assets_019e219f-7715-7e8a-b48c-60b57abe7811" xlink:to="loc_us-gaap_AssetsCurrent_019e219f-7715-7d78-8cda-b5c80824cdea" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_clh_AssetsNoncurrentExcludingPropertyPlantAndEquipment_019e219f-7715-72b1-be8f-4b64b593652d" xlink:href="clh-20260630.xsd#clh_AssetsNoncurrentExcludingPropertyPlantAndEquipment"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_Assets_019e219f-7715-7e8a-b48c-60b57abe7811" xlink:to="loc_clh_AssetsNoncurrentExcludingPropertyPlantAndEquipment_019e219f-7715-72b1-be8f-4b64b593652d" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentAndFinanceLeaseRightOfUseAssetAfterAccumulatedDepreciationAndAmortization_019e219f-7715-798a-86c5-e8611c2e01a9" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_PropertyPlantAndEquipmentAndFinanceLeaseRightOfUseAssetAfterAccumulatedDepreciationAndAmortization"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_Assets_019e219f-7715-7e8a-b48c-60b57abe7811" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentAndFinanceLeaseRightOfUseAssetAfterAccumulatedDepreciationAndAmortization_019e219f-7715-798a-86c5-e8611c2e01a9" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LiabilitiesAndStockholdersEquity_019e219f-7715-7da4-bc9e-1f04a9d16aa6" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_LiabilitiesAndStockholdersEquity"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockholdersEquity_019e219f-7715-7184-938f-70419d5f5487" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_StockholdersEquity"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquity_019e219f-7715-7da4-bc9e-1f04a9d16aa6" xlink:to="loc_us-gaap_StockholdersEquity_019e219f-7715-7184-938f-70419d5f5487" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LiabilitiesNoncurrent_019e219f-7715-79d9-b1b9-29c6bde4074f" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_LiabilitiesNoncurrent"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquity_019e219f-7715-7da4-bc9e-1f04a9d16aa6" xlink:to="loc_us-gaap_LiabilitiesNoncurrent_019e219f-7715-79d9-b1b9-29c6bde4074f" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LiabilitiesCurrent_019e219f-7715-7b90-b230-f53526f5b15f" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_LiabilitiesCurrent"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquity_019e219f-7715-7da4-bc9e-1f04a9d16aa6" xlink:to="loc_us-gaap_LiabilitiesCurrent_019e219f-7715-7b90-b230-f53526f5b15f" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommitmentsAndContingencies_019e219f-7715-798a-8ade-46638e127639" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_CommitmentsAndContingencies"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquity_019e219f-7715-7da4-bc9e-1f04a9d16aa6" xlink:to="loc_us-gaap_CommitmentsAndContingencies_019e219f-7715-798a-8ade-46638e127639" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockholdersEquity_019e219f-7715-73b6-8206-88edf1a92c3a" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_StockholdersEquity"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockValue_019e219f-7715-77db-882f-ec099f723c70" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_CommonStockValue"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_StockholdersEquity_019e219f-7715-73b6-8206-88edf1a92c3a" xlink:to="loc_us-gaap_CommonStockValue_019e219f-7715-77db-882f-ec099f723c70" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AdditionalPaidInCapitalCommonStock_019e219f-7715-7e86-bfe8-5f4362205f6b" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_AdditionalPaidInCapitalCommonStock"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_StockholdersEquity_019e219f-7715-73b6-8206-88edf1a92c3a" xlink:to="loc_us-gaap_AdditionalPaidInCapitalCommonStock_019e219f-7715-7e86-bfe8-5f4362205f6b" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax_019e219f-7715-7dd5-9b8d-617880bb0ff9" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_StockholdersEquity_019e219f-7715-73b6-8206-88edf1a92c3a" xlink:to="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax_019e219f-7715-7dd5-9b8d-617880bb0ff9" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RetainedEarningsAccumulatedDeficit_019e219f-7715-7a6a-9357-01ec6a532411" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_RetainedEarningsAccumulatedDeficit"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_StockholdersEquity_019e219f-7715-73b6-8206-88edf1a92c3a" xlink:to="loc_us-gaap_RetainedEarningsAccumulatedDeficit_019e219f-7715-7a6a-9357-01ec6a532411" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.cleanharbors.com/role/UNAUDITEDCONSOLIDATEDSTATEMENTSOFOPERATIONS" xlink:type="simple" xlink:href="clh-20260630.xsd#UNAUDITEDCONSOLIDATEDSTATEMENTSOFOPERATIONS"/>
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/UNAUDITEDCONSOLIDATEDSTATEMENTSOFOPERATIONS" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetIncomeLoss_019e219f-7715-7d28-b5e7-6af4b0dc5954" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_NetIncomeLoss"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest_019e219f-7715-78fa-ab40-e958fed3ba1c" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_NetIncomeLoss_019e219f-7715-7d28-b5e7-6af4b0dc5954" xlink:to="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest_019e219f-7715-78fa-ab40-e958fed3ba1c" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeTaxExpenseBenefit_019e219f-7715-7d62-b464-934a2f2b7a19" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_IncomeTaxExpenseBenefit"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_NetIncomeLoss_019e219f-7715-7d28-b5e7-6af4b0dc5954" xlink:to="loc_us-gaap_IncomeTaxExpenseBenefit_019e219f-7715-7d62-b464-934a2f2b7a19" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingIncomeLoss_019e219f-7715-7178-87ee-deb8d743b921" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_OperatingIncomeLoss"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax_019e219f-7715-77db-b188-73d43699bfa4" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_OperatingIncomeLoss_019e219f-7715-7178-87ee-deb8d743b921" xlink:to="loc_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax_019e219f-7715-77db-b188-73d43699bfa4" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CostOfGoodsAndServicesSold_019e219f-7715-774c-aa17-c469021e1e5f" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_CostOfGoodsAndServicesSold"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_OperatingIncomeLoss_019e219f-7715-7178-87ee-deb8d743b921" xlink:to="loc_us-gaap_CostOfGoodsAndServicesSold_019e219f-7715-774c-aa17-c469021e1e5f" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SellingGeneralAndAdministrativeExpense_019e219f-7715-7f9b-931e-19f125afc8c3" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_SellingGeneralAndAdministrativeExpense"/>
    <link:calculationArc order="3" weight="-1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_OperatingIncomeLoss_019e219f-7715-7178-87ee-deb8d743b921" xlink:to="loc_us-gaap_SellingGeneralAndAdministrativeExpense_019e219f-7715-7f9b-931e-19f125afc8c3" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_clh_AccretionOfEnvironmentalLiabilities_019e219f-7715-7b7a-a507-afa436fd705c" xlink:href="clh-20260630.xsd#clh_AccretionOfEnvironmentalLiabilities"/>
    <link:calculationArc order="4" weight="-1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_OperatingIncomeLoss_019e219f-7715-7178-87ee-deb8d743b921" xlink:to="loc_clh_AccretionOfEnvironmentalLiabilities_019e219f-7715-7b7a-a507-afa436fd705c" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DepreciationDepletionAndAmortization_019e219f-7715-7f3b-9f6f-9c083d9cd12a" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DepreciationDepletionAndAmortization"/>
    <link:calculationArc order="5" weight="-1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_OperatingIncomeLoss_019e219f-7715-7178-87ee-deb8d743b921" xlink:to="loc_us-gaap_DepreciationDepletionAndAmortization_019e219f-7715-7f3b-9f6f-9c083d9cd12a" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest_019e219f-7715-752c-8da6-8d261f424a03" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingIncomeLoss_019e219f-7715-76d3-843d-1e26206b4d48" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_OperatingIncomeLoss"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest_019e219f-7715-752c-8da6-8d261f424a03" xlink:to="loc_us-gaap_OperatingIncomeLoss_019e219f-7715-76d3-843d-1e26206b4d48" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherNonoperatingIncomeExpense_019e219f-7715-74c0-9023-f9f41e14bc6b" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_OtherNonoperatingIncomeExpense"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest_019e219f-7715-752c-8da6-8d261f424a03" xlink:to="loc_us-gaap_OtherNonoperatingIncomeExpense_019e219f-7715-74c0-9023-f9f41e14bc6b" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestIncomeExpenseNonoperatingNet_019e219f-7715-7a05-8581-0894dee6425d" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_InterestIncomeExpenseNonoperatingNet"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest_019e219f-7715-752c-8da6-8d261f424a03" xlink:to="loc_us-gaap_InterestIncomeExpenseNonoperatingNet_019e219f-7715-7a05-8581-0894dee6425d" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.cleanharbors.com/role/UNAUDITEDCONSOLIDATEDSTATEMENTSOFCOMPREHENSIVEINCOME" xlink:type="simple" xlink:href="clh-20260630.xsd#UNAUDITEDCONSOLIDATEDSTATEMENTSOFCOMPREHENSIVEINCOME"/>
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/UNAUDITEDCONSOLIDATEDSTATEMENTSOFCOMPREHENSIVEINCOME" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ComprehensiveIncomeNetOfTax_019e219f-7715-7001-a592-113d283fadfa" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ComprehensiveIncomeNetOfTax"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetIncomeLoss_019e219f-7715-7e77-b1d2-d96dc4ff1714" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_NetIncomeLoss"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_ComprehensiveIncomeNetOfTax_019e219f-7715-7001-a592-113d283fadfa" xlink:to="loc_us-gaap_NetIncomeLoss_019e219f-7715-7e77-b1d2-d96dc4ff1714" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent_019e219f-7715-7fb5-8787-b631fdea7804" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_ComprehensiveIncomeNetOfTax_019e219f-7715-7001-a592-113d283fadfa" xlink:to="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent_019e219f-7715-7fb5-8787-b631fdea7804" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent_019e219f-7715-731a-9127-96bf6fd99031" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent"/>
    <link:loc xlink:type="locator" xlink:label="loc_clh_OtherComprehensiveIncomeLossCashFlowHedgeGainLossReclassificationRealizedInNetIncomeAfterTax_019e219f-7715-7c24-8a30-4b8c88b4293b" xlink:href="clh-20260630.xsd#clh_OtherComprehensiveIncomeLossCashFlowHedgeGainLossReclassificationRealizedInNetIncomeAfterTax"/>
    <link:calculationArc order="1" weight="-1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent_019e219f-7715-731a-9127-96bf6fd99031" xlink:to="loc_clh_OtherComprehensiveIncomeLossCashFlowHedgeGainLossReclassificationRealizedInNetIncomeAfterTax_019e219f-7715-7c24-8a30-4b8c88b4293b" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationAdjustmentNetOfTaxPortionAttributableToParent_019e219f-7715-792e-958c-7c4691039608" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationAdjustmentNetOfTaxPortionAttributableToParent"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent_019e219f-7715-731a-9127-96bf6fd99031" xlink:to="loc_us-gaap_OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationAdjustmentNetOfTaxPortionAttributableToParent_019e219f-7715-792e-958c-7c4691039608" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossCashFlowHedgeGainLossBeforeReclassificationAfterTax_019e219f-7715-7d0a-98ff-a1bd79d3e0b7" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_OtherComprehensiveIncomeLossCashFlowHedgeGainLossBeforeReclassificationAfterTax"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent_019e219f-7715-731a-9127-96bf6fd99031" xlink:to="loc_us-gaap_OtherComprehensiveIncomeLossCashFlowHedgeGainLossBeforeReclassificationAfterTax_019e219f-7715-7d0a-98ff-a1bd79d3e0b7" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeAvailableforsaleSecuritiesAdjustmentNetOfTaxPortionAttributableToParent_019e219f-7715-7c86-b5b1-2ccbdd5eda4a" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_OtherComprehensiveIncomeAvailableforsaleSecuritiesAdjustmentNetOfTaxPortionAttributableToParent"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent_019e219f-7715-731a-9127-96bf6fd99031" xlink:to="loc_us-gaap_OtherComprehensiveIncomeAvailableforsaleSecuritiesAdjustmentNetOfTaxPortionAttributableToParent_019e219f-7715-7c86-b5b1-2ccbdd5eda4a" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeDefinedBenefitPlansAdjustmentNetOfTaxPortionAttributableToParent_019e219f-7715-71fb-a000-d98e8f982ec3" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_OtherComprehensiveIncomeDefinedBenefitPlansAdjustmentNetOfTaxPortionAttributableToParent"/>
    <link:calculationArc order="5" weight="-1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent_019e219f-7715-731a-9127-96bf6fd99031" xlink:to="loc_us-gaap_OtherComprehensiveIncomeDefinedBenefitPlansAdjustmentNetOfTaxPortionAttributableToParent_019e219f-7715-71fb-a000-d98e8f982ec3" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.cleanharbors.com/role/UNAUDITEDCONSOLIDATEDSTATEMENTSOFCASHFLOWS" xlink:type="simple" xlink:href="clh-20260630.xsd#UNAUDITEDCONSOLIDATEDSTATEMENTSOFCASHFLOWS"/>
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/UNAUDITEDCONSOLIDATEDSTATEMENTSOFCASHFLOWS" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_019e219f-7715-7116-a87f-259266b9db91" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_NetCashProvidedByUsedInOperatingActivities"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetIncomeLoss_019e219f-7715-7115-8ccf-c1ae97c587fc" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_NetIncomeLoss"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_019e219f-7715-7116-a87f-259266b9db91" xlink:to="loc_us-gaap_NetIncomeLoss_019e219f-7715-7115-8ccf-c1ae97c587fc" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProvisionForDoubtfulAccounts_019e219f-7715-7e93-b9b6-7d322a0a0c60" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ProvisionForDoubtfulAccounts"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_019e219f-7715-7116-a87f-259266b9db91" xlink:to="loc_us-gaap_ProvisionForDoubtfulAccounts_019e219f-7715-7e93-b9b6-7d322a0a0c60" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherNoncashIncomeExpense_019e219f-7715-7d2e-a5bb-4a62270e6a4f" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_OtherNoncashIncomeExpense"/>
    <link:calculationArc order="3" weight="-1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_019e219f-7715-7116-a87f-259266b9db91" xlink:to="loc_us-gaap_OtherNoncashIncomeExpense_019e219f-7715-7d2e-a5bb-4a62270e6a4f" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AmortizationOfFinancingCostsAndDiscounts_019e219f-7715-7b42-8332-e7761587c11f" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_AmortizationOfFinancingCostsAndDiscounts"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_019e219f-7715-7116-a87f-259266b9db91" xlink:to="loc_us-gaap_AmortizationOfFinancingCostsAndDiscounts_019e219f-7715-7b42-8332-e7761587c11f" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInAccountsPayable_019e219f-7715-7c9d-a79a-e0d3b87d6198" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_IncreaseDecreaseInAccountsPayable"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_019e219f-7715-7116-a87f-259266b9db91" xlink:to="loc_us-gaap_IncreaseDecreaseInAccountsPayable_019e219f-7715-7c9d-a79a-e0d3b87d6198" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_clh_AccretionOfEnvironmentalLiabilities_019e219f-7715-7f78-ae1a-201a453fdfa0" xlink:href="clh-20260630.xsd#clh_AccretionOfEnvironmentalLiabilities"/>
    <link:calculationArc order="6" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_019e219f-7715-7116-a87f-259266b9db91" xlink:to="loc_clh_AccretionOfEnvironmentalLiabilities_019e219f-7715-7f78-ae1a-201a453fdfa0" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsForEnvironmentalLiabilities_019e219f-7715-79ec-9d74-71805e29f2cc" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_PaymentsForEnvironmentalLiabilities"/>
    <link:calculationArc order="7" weight="-1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_019e219f-7715-7116-a87f-259266b9db91" xlink:to="loc_us-gaap_PaymentsForEnvironmentalLiabilities_019e219f-7715-79ec-9d74-71805e29f2cc" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInOtherOperatingAssets_019e219f-7715-7742-9185-40e2054c6ece" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_IncreaseDecreaseInOtherOperatingAssets"/>
    <link:calculationArc order="8" weight="-1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_019e219f-7715-7116-a87f-259266b9db91" xlink:to="loc_us-gaap_IncreaseDecreaseInOtherOperatingAssets_019e219f-7715-7742-9185-40e2054c6ece" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInOtherOperatingLiabilities_019e219f-7715-7457-8e88-a68860fb579c" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_IncreaseDecreaseInOtherOperatingLiabilities"/>
    <link:calculationArc order="9" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_019e219f-7715-7116-a87f-259266b9db91" xlink:to="loc_us-gaap_IncreaseDecreaseInOtherOperatingLiabilities_019e219f-7715-7457-8e88-a68860fb579c" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInInventories_019e219f-7715-7e07-968a-1178aac35276" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_IncreaseDecreaseInInventories"/>
    <link:calculationArc order="10" weight="-1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_019e219f-7715-7116-a87f-259266b9db91" xlink:to="loc_us-gaap_IncreaseDecreaseInInventories_019e219f-7715-7e07-968a-1178aac35276" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DepreciationDepletionAndAmortization_019e219f-7715-7beb-a668-c943257555fb" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DepreciationDepletionAndAmortization"/>
    <link:calculationArc order="11" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_019e219f-7715-7116-a87f-259266b9db91" xlink:to="loc_us-gaap_DepreciationDepletionAndAmortization_019e219f-7715-7beb-a668-c943257555fb" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherIncreaseDecreaseInEnvironmentalLiabilities_019e219f-7715-71a5-ae1a-f358caeda1a7" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_OtherIncreaseDecreaseInEnvironmentalLiabilities"/>
    <link:calculationArc order="12" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_019e219f-7715-7116-a87f-259266b9db91" xlink:to="loc_us-gaap_OtherIncreaseDecreaseInEnvironmentalLiabilities_019e219f-7715-71a5-ae1a-f358caeda1a7" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInAccountsReceivable_019e219f-7715-7694-837e-9bd002a3b21a" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_IncreaseDecreaseInAccountsReceivable"/>
    <link:calculationArc order="13" weight="-1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_019e219f-7715-7116-a87f-259266b9db91" xlink:to="loc_us-gaap_IncreaseDecreaseInAccountsReceivable_019e219f-7715-7694-837e-9bd002a3b21a" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensation_019e219f-7715-7506-b34b-49f275a3172b" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ShareBasedCompensation"/>
    <link:calculationArc order="14" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_019e219f-7715-7116-a87f-259266b9db91" xlink:to="loc_us-gaap_ShareBasedCompensation_019e219f-7715-7506-b34b-49f275a3172b" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_019e219f-7715-72f9-bb05-8967b59a59b4" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_NetCashProvidedByUsedInInvestingActivities"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsToAcquireBusinessesNetOfCashAcquired_019e219f-7715-7461-950b-e4f126a9f691" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_PaymentsToAcquireBusinessesNetOfCashAcquired"/>
    <link:calculationArc order="1" weight="-1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_019e219f-7715-72f9-bb05-8967b59a59b4" xlink:to="loc_us-gaap_PaymentsToAcquireBusinessesNetOfCashAcquired_019e219f-7715-7461-950b-e4f126a9f691" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsToAcquirePropertyPlantAndEquipment_019e219f-7715-79c6-8089-f4190befb9ff" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_PaymentsToAcquirePropertyPlantAndEquipment"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_019e219f-7715-72f9-bb05-8967b59a59b4" xlink:to="loc_us-gaap_PaymentsToAcquirePropertyPlantAndEquipment_019e219f-7715-79c6-8089-f4190befb9ff" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsToAcquireAvailableForSaleSecuritiesDebt_019e219f-7715-7658-be23-ffb2adf14d30" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_PaymentsToAcquireAvailableForSaleSecuritiesDebt"/>
    <link:calculationArc order="3" weight="-1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_019e219f-7715-72f9-bb05-8967b59a59b4" xlink:to="loc_us-gaap_PaymentsToAcquireAvailableForSaleSecuritiesDebt_019e219f-7715-7658-be23-ffb2adf14d30" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromSaleOfPropertyPlantAndEquipment_019e219f-7715-71d9-8f9f-7a5ee2b52c23" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ProceedsFromSaleOfPropertyPlantAndEquipment"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_019e219f-7715-72f9-bb05-8967b59a59b4" xlink:to="loc_us-gaap_ProceedsFromSaleOfPropertyPlantAndEquipment_019e219f-7715-71d9-8f9f-7a5ee2b52c23" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsToAcquireIntangibleAssets_019e219f-7715-7074-aace-8814d65289e3" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_PaymentsToAcquireIntangibleAssets"/>
    <link:calculationArc order="5" weight="-1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_019e219f-7715-72f9-bb05-8967b59a59b4" xlink:to="loc_us-gaap_PaymentsToAcquireIntangibleAssets_019e219f-7715-7074-aace-8814d65289e3" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromSaleOfAvailableForSaleSecuritiesDebt_019e219f-7715-7136-85f8-d4d628969ea8" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ProceedsFromSaleOfAvailableForSaleSecuritiesDebt"/>
    <link:calculationArc order="6" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_019e219f-7715-72f9-bb05-8967b59a59b4" xlink:to="loc_us-gaap_ProceedsFromSaleOfAvailableForSaleSecuritiesDebt_019e219f-7715-7136-85f8-d4d628969ea8" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_019e219f-7715-752c-8841-40a4c2cdbe21" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_NetCashProvidedByUsedInFinancingActivities"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsRelatedToTaxWithholdingForShareBasedCompensation_019e219f-7715-74ba-800b-06ac241441ce" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_PaymentsRelatedToTaxWithholdingForShareBasedCompensation"/>
    <link:calculationArc order="1" weight="-1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_019e219f-7715-752c-8841-40a4c2cdbe21" xlink:to="loc_us-gaap_PaymentsRelatedToTaxWithholdingForShareBasedCompensation_019e219f-7715-74ba-800b-06ac241441ce" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinanceLeasePrincipalPayments_019e219f-7715-70ab-b93a-22b4b2891764" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_FinanceLeasePrincipalPayments"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_019e219f-7715-752c-8841-40a4c2cdbe21" xlink:to="loc_us-gaap_FinanceLeasePrincipalPayments_019e219f-7715-70ab-b93a-22b4b2891764" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsForRepurchaseOfCommonStock_019e219f-7715-72a0-979d-a330a92b7dd6" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_PaymentsForRepurchaseOfCommonStock"/>
    <link:calculationArc order="3" weight="-1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_019e219f-7715-752c-8841-40a4c2cdbe21" xlink:to="loc_us-gaap_PaymentsForRepurchaseOfCommonStock_019e219f-7715-72a0-979d-a330a92b7dd6" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInOutstandingChecksFinancingActivities_019e219f-7715-70dd-b455-f5962a658836" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_IncreaseDecreaseInOutstandingChecksFinancingActivities"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_019e219f-7715-752c-8841-40a4c2cdbe21" xlink:to="loc_us-gaap_IncreaseDecreaseInOutstandingChecksFinancingActivities_019e219f-7715-70dd-b455-f5962a658836" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RepaymentsOfLongTermDebt_019e219f-7715-73b4-88f1-b18bb85581df" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_RepaymentsOfLongTermDebt"/>
    <link:calculationArc order="5" weight="-1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_019e219f-7715-752c-8841-40a4c2cdbe21" xlink:to="loc_us-gaap_RepaymentsOfLongTermDebt_019e219f-7715-73b4-88f1-b18bb85581df" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromStockPlans_019e2b2b-a034-792d-8d4d-ce190c4b26c6" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ProceedsFromStockPlans"/>
    <link:calculationArc order="6" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_019e219f-7715-752c-8841-40a4c2cdbe21" xlink:to="loc_us-gaap_ProceedsFromStockPlans_019e2b2b-a034-792d-8d4d-ce190c4b26c6" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsOfFinancingCosts_019f7062-f805-77e2-9d8e-8486adcfa543" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_PaymentsOfFinancingCosts"/>
    <link:calculationArc order="7" weight="-1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_019e219f-7715-752c-8841-40a4c2cdbe21" xlink:to="loc_us-gaap_PaymentsOfFinancingCosts_019f7062-f805-77e2-9d8e-8486adcfa543" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect_019e219f-7715-7199-a03d-69056bda4a2a" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EffectOfExchangeRateOnCashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_019e219f-7715-7a03-af2c-8bb4f6fca371" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_EffectOfExchangeRateOnCashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect_019e219f-7715-7199-a03d-69056bda4a2a" xlink:to="loc_us-gaap_EffectOfExchangeRateOnCashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_019e219f-7715-7a03-af2c-8bb4f6fca371" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_019e219f-7715-78bb-8d79-bfeb9aa55120" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_NetCashProvidedByUsedInFinancingActivities"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect_019e219f-7715-7199-a03d-69056bda4a2a" xlink:to="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_019e219f-7715-78bb-8d79-bfeb9aa55120" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_019e219f-7715-7ff6-a8c6-ad2199ce6b64" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_NetCashProvidedByUsedInOperatingActivities"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect_019e219f-7715-7199-a03d-69056bda4a2a" xlink:to="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_019e219f-7715-7ff6-a8c6-ad2199ce6b64" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_019e219f-7715-7738-8753-be49d9bc8ab4" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_NetCashProvidedByUsedInInvestingActivities"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect_019e219f-7715-7199-a03d-69056bda4a2a" xlink:to="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_019e219f-7715-7738-8753-be49d9bc8ab4" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.cleanharbors.com/role/BUSINESSCOMBINATIONSAssetsAcquiredandLiabilitiesAssumedDetails" xlink:type="simple" xlink:href="clh-20260630.xsd#BUSINESSCOMBINATIONSAssetsAcquiredandLiabilitiesAssumedDetails"/>
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/BUSINESSCOMBINATIONSAssetsAcquiredandLiabilitiesAssumedDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_clh_BusinessCombinationProvisionalInformationInitialAccountingIncompleteAdjustmentAssetsAcquiredAndLiabilitiesAssumedNet_019e2b8a-29ad-7a86-ad67-bc600a6ad68d" xlink:href="clh-20260630.xsd#clh_BusinessCombinationProvisionalInformationInitialAccountingIncompleteAdjustmentAssetsAcquiredAndLiabilitiesAssumedNet"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessCombinationProvisionalInformationInitialAccountingIncompleteAdjustmentIntangibles_019f8c99-4a71-7acc-880f-a69cd88cc1dc" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_BusinessCombinationProvisionalInformationInitialAccountingIncompleteAdjustmentIntangibles"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_clh_BusinessCombinationProvisionalInformationInitialAccountingIncompleteAdjustmentAssetsAcquiredAndLiabilitiesAssumedNet_019e2b8a-29ad-7a86-ad67-bc600a6ad68d" xlink:to="loc_us-gaap_BusinessCombinationProvisionalInformationInitialAccountingIncompleteAdjustmentIntangibles_019f8c99-4a71-7acc-880f-a69cd88cc1dc" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessCombinationProvisionalInformationInitialAccountingIncompleteAdjustmentPropertyPlantAndEquipment_019e2b8a-29ad-7dbb-9095-7e13d39b740a" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_BusinessCombinationProvisionalInformationInitialAccountingIncompleteAdjustmentPropertyPlantAndEquipment"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_clh_BusinessCombinationProvisionalInformationInitialAccountingIncompleteAdjustmentAssetsAcquiredAndLiabilitiesAssumedNet_019e2b8a-29ad-7a86-ad67-bc600a6ad68d" xlink:to="loc_us-gaap_BusinessCombinationProvisionalInformationInitialAccountingIncompleteAdjustmentPropertyPlantAndEquipment_019e2b8a-29ad-7dbb-9095-7e13d39b740a" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredGoodwillAndLiabilitiesAssumedNet_019e219f-7715-7909-b318-80989bb5ff48" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredGoodwillAndLiabilitiesAssumedNet"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_Goodwill_019e219f-7715-7512-9f85-73f151656684" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_Goodwill"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredGoodwillAndLiabilitiesAssumedNet_019e219f-7715-7909-b318-80989bb5ff48" xlink:to="loc_us-gaap_Goodwill_019e219f-7715-7512-9f85-73f151656684" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedNet_019e219f-7715-7803-a71a-7390d3c50d37" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedNet"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredGoodwillAndLiabilitiesAssumedNet_019e219f-7715-7909-b318-80989bb5ff48" xlink:to="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedNet_019e219f-7715-7803-a71a-7390d3c50d37" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedNet_019e2b86-9b8a-70bf-8cd3-83ca93886daf" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedNet"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedCurrentAssetsReceivables_019e2b86-9b8a-743a-b485-ae65cb55e29f" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedCurrentAssetsReceivables"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedNet_019e2b86-9b8a-70bf-8cd3-83ca93886daf" xlink:to="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedCurrentAssetsReceivables_019e2b86-9b8a-743a-b485-ae65cb55e29f" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedInventory_019e2b86-9b8a-7744-9eb4-5128f5203c1e" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedInventory"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedNet_019e2b86-9b8a-70bf-8cd3-83ca93886daf" xlink:to="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedInventory_019e2b86-9b8a-7744-9eb4-5128f5203c1e" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedCurrentAssetsPrepaidExpenseAndOtherAssets_019e2b86-9b8a-78a3-b6ba-443f7cb2ea05" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedCurrentAssetsPrepaidExpenseAndOtherAssets"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedNet_019e2b86-9b8a-70bf-8cd3-83ca93886daf" xlink:to="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedCurrentAssetsPrepaidExpenseAndOtherAssets_019e2b86-9b8a-78a3-b6ba-443f7cb2ea05" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedPropertyPlantAndEquipment_019e2b86-9b8a-7e35-aae5-573434a7481c" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedPropertyPlantAndEquipment"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedNet_019e2b86-9b8a-70bf-8cd3-83ca93886daf" xlink:to="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedPropertyPlantAndEquipment_019e2b86-9b8a-7e35-aae5-573434a7481c" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedIntangibleAssetsOtherThanGoodwill_019e2b86-9b8a-70bb-84a3-1abb504fd2d6" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedIntangibleAssetsOtherThanGoodwill"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedNet_019e2b86-9b8a-70bf-8cd3-83ca93886daf" xlink:to="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedIntangibleAssetsOtherThanGoodwill_019e2b86-9b8a-70bb-84a3-1abb504fd2d6" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_clh_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedOperatingLeaseRightOfUseAsset_019e2b86-9b8a-76ba-b054-137c17c4ffdb" xlink:href="clh-20260630.xsd#clh_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedOperatingLeaseRightOfUseAsset"/>
    <link:calculationArc order="6" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedNet_019e2b86-9b8a-70bf-8cd3-83ca93886daf" xlink:to="loc_clh_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedOperatingLeaseRightOfUseAsset_019e2b86-9b8a-76ba-b054-137c17c4ffdb" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedCurrentLiabilitiesAccountsPayable_019e2b86-9b8a-7fb2-ab0b-b601ecda2140" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedCurrentLiabilitiesAccountsPayable"/>
    <link:calculationArc order="7" weight="-1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedNet_019e2b86-9b8a-70bf-8cd3-83ca93886daf" xlink:to="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedCurrentLiabilitiesAccountsPayable_019e2b86-9b8a-7fb2-ab0b-b601ecda2140" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_clh_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedAccruedAndOtherCurrentLiabilities_019e2b86-9b8a-7fda-b13e-e8321e6b0918" xlink:href="clh-20260630.xsd#clh_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedAccruedAndOtherCurrentLiabilities"/>
    <link:calculationArc order="8" weight="-1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedNet_019e2b86-9b8a-70bf-8cd3-83ca93886daf" xlink:to="loc_clh_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedAccruedAndOtherCurrentLiabilities_019e2b86-9b8a-7fda-b13e-e8321e6b0918" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_clh_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedCurrentLiabilitiesOperatingLease_019e2b86-9b8a-7136-a48e-b8ec005cc2b7" xlink:href="clh-20260630.xsd#clh_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedCurrentLiabilitiesOperatingLease"/>
    <link:calculationArc order="9" weight="-1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedNet_019e2b86-9b8a-70bf-8cd3-83ca93886daf" xlink:to="loc_clh_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedCurrentLiabilitiesOperatingLease_019e2b86-9b8a-7136-a48e-b8ec005cc2b7" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_clh_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedOperatingLeaseLiabilitiesLessCurrentPortion_019e2b86-9b8a-7b43-b98b-fe2a6b6f81e9" xlink:href="clh-20260630.xsd#clh_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedOperatingLeaseLiabilitiesLessCurrentPortion"/>
    <link:calculationArc order="10" weight="-1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedNet_019e2b86-9b8a-70bf-8cd3-83ca93886daf" xlink:to="loc_clh_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedOperatingLeaseLiabilitiesLessCurrentPortion_019e2b86-9b8a-7b43-b98b-fe2a6b6f81e9" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedOtherNoncurrentAssets_019f8a6d-67f5-76f3-a612-e1c5f3629bbc" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedOtherNoncurrentAssets"/>
    <link:calculationArc order="11" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedNet_019e2b86-9b8a-70bf-8cd3-83ca93886daf" xlink:to="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedOtherNoncurrentAssets_019f8a6d-67f5-76f3-a612-e1c5f3629bbc" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessCombinationProvisionalInformationInitialAccountingIncompleteAdjustmentConsiderationTransferred_019e2b8a-583a-7fda-abb8-0eed6c8e467b" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_BusinessCombinationProvisionalInformationInitialAccountingIncompleteAdjustmentConsiderationTransferred"/>
    <link:loc xlink:type="locator" xlink:label="loc_clh_BusinessCombinationProvisionalInformationInitialAccountingIncompleteAdjustmentAssetsAcquiredAndLiabilitiesAssumedNet_019e2b8a-583a-78bd-b585-0841b775d8c0" xlink:href="clh-20260630.xsd#clh_BusinessCombinationProvisionalInformationInitialAccountingIncompleteAdjustmentAssetsAcquiredAndLiabilitiesAssumedNet"/>
    <link:calculationArc order="1" weight="-1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_BusinessCombinationProvisionalInformationInitialAccountingIncompleteAdjustmentConsiderationTransferred_019e2b8a-583a-7fda-abb8-0eed6c8e467b" xlink:to="loc_clh_BusinessCombinationProvisionalInformationInitialAccountingIncompleteAdjustmentAssetsAcquiredAndLiabilitiesAssumedNet_019e2b8a-583a-78bd-b585-0841b775d8c0" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_GoodwillPurchaseAccountingAdjustments_019e2b8a-583a-7da2-88b9-fd127005b186" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_GoodwillPurchaseAccountingAdjustments"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_BusinessCombinationProvisionalInformationInitialAccountingIncompleteAdjustmentConsiderationTransferred_019e2b8a-583a-7fda-abb8-0eed6c8e467b" xlink:to="loc_us-gaap_GoodwillPurchaseAccountingAdjustments_019e2b8a-583a-7da2-88b9-fd127005b186" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.cleanharbors.com/role/PROPERTYPLANTANDEQUIPMENTScheduleofPropertyPlantandEquipmentDetails" xlink:type="simple" xlink:href="clh-20260630.xsd#PROPERTYPLANTANDEQUIPMENTScheduleofPropertyPlantandEquipmentDetails"/>
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/PROPERTYPLANTANDEQUIPMENTScheduleofPropertyPlantandEquipmentDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentAndFinanceLeaseRightOfUseAssetAfterAccumulatedDepreciationAndAmortization_019e219f-7715-7ff7-b090-5d78fb3caf13" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_PropertyPlantAndEquipmentAndFinanceLeaseRightOfUseAssetAfterAccumulatedDepreciationAndAmortization"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentAndFinanceLeaseRightOfUseAssetBeforeAccumulatedDepreciationAndAmortization_019e219f-7715-725b-8c1c-17577f015c57" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_PropertyPlantAndEquipmentAndFinanceLeaseRightOfUseAssetBeforeAccumulatedDepreciationAndAmortization"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentAndFinanceLeaseRightOfUseAssetAfterAccumulatedDepreciationAndAmortization_019e219f-7715-7ff7-b090-5d78fb3caf13" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentAndFinanceLeaseRightOfUseAssetBeforeAccumulatedDepreciationAndAmortization_019e219f-7715-725b-8c1c-17577f015c57" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentAndFinanceLeaseRightOfUseAssetAccumulatedDepreciationAndAmortization_019e219f-7715-70ad-8e3b-d59804867a16" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_PropertyPlantAndEquipmentAndFinanceLeaseRightOfUseAssetAccumulatedDepreciationAndAmortization"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentAndFinanceLeaseRightOfUseAssetAfterAccumulatedDepreciationAndAmortization_019e219f-7715-7ff7-b090-5d78fb3caf13" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentAndFinanceLeaseRightOfUseAssetAccumulatedDepreciationAndAmortization_019e219f-7715-70ad-8e3b-d59804867a16" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.cleanharbors.com/role/GOODWILLANDOTHERINTANGIBLEASSETSFinitelivedandIndefiniteLivedIntangibleAssetsDetails" xlink:type="simple" xlink:href="clh-20260630.xsd#GOODWILLANDOTHERINTANGIBLEASSETSFinitelivedandIndefiniteLivedIntangibleAssetsDetails"/>
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/GOODWILLANDOTHERINTANGIBLEASSETSFinitelivedandIndefiniteLivedIntangibleAssetsDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IntangibleAssetsGrossExcludingGoodwill_019e219f-7715-775a-aeeb-cfec525670ad" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_IntangibleAssetsGrossExcludingGoodwill"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsGross_019e219f-7715-7936-9708-e1f08672c41c" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_FiniteLivedIntangibleAssetsGross"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_IntangibleAssetsGrossExcludingGoodwill_019e219f-7715-775a-aeeb-cfec525670ad" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsGross_019e219f-7715-7936-9708-e1f08672c41c" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IndefiniteLivedIntangibleAssetsExcludingGoodwill_019e219f-7715-7550-af32-05bc1ced58f6" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_IndefiniteLivedIntangibleAssetsExcludingGoodwill"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_IntangibleAssetsGrossExcludingGoodwill_019e219f-7715-775a-aeeb-cfec525670ad" xlink:to="loc_us-gaap_IndefiniteLivedIntangibleAssetsExcludingGoodwill_019e219f-7715-7550-af32-05bc1ced58f6" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsNet_019e219f-7715-7656-97a6-c9a278f2d04f" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_FiniteLivedIntangibleAssetsNet"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsGross_019e219f-7715-78e8-991f-29bdbf0d365d" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_FiniteLivedIntangibleAssetsGross"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsNet_019e219f-7715-7656-97a6-c9a278f2d04f" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsGross_019e219f-7715-78e8-991f-29bdbf0d365d" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAccumulatedAmortization_019e219f-7715-7a37-93a1-1e74b031bd39" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_FiniteLivedIntangibleAssetsAccumulatedAmortization"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsNet_019e219f-7715-7656-97a6-c9a278f2d04f" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsAccumulatedAmortization_019e219f-7715-7a37-93a1-1e74b031bd39" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IntangibleAssetsNetExcludingGoodwill_019e219f-7715-7214-bef4-c5ef11e2b96d" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_IntangibleAssetsNetExcludingGoodwill"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsNet_019e219f-7715-72d2-9a57-74969699fc6c" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_FiniteLivedIntangibleAssetsNet"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_IntangibleAssetsNetExcludingGoodwill_019e219f-7715-7214-bef4-c5ef11e2b96d" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsNet_019e219f-7715-72d2-9a57-74969699fc6c" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IndefiniteLivedIntangibleAssetsExcludingGoodwill_019e219f-7715-72c0-b57d-89ec5bf1e080" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_IndefiniteLivedIntangibleAssetsExcludingGoodwill"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_IntangibleAssetsNetExcludingGoodwill_019e219f-7715-7214-bef4-c5ef11e2b96d" xlink:to="loc_us-gaap_IndefiniteLivedIntangibleAssetsExcludingGoodwill_019e219f-7715-72c0-b57d-89ec5bf1e080" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.cleanharbors.com/role/GOODWILLANDOTHERINTANGIBLEASSETSFinitelivedandIndefiniteLivedIntangibleAssetsDetails_1" xlink:type="simple" xlink:href="clh-20260630.xsd#GOODWILLANDOTHERINTANGIBLEASSETSFinitelivedandIndefiniteLivedIntangibleAssetsDetails_1"/>
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/GOODWILLANDOTHERINTANGIBLEASSETSFinitelivedandIndefiniteLivedIntangibleAssetsDetails_1" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IntangibleAssetsNetExcludingGoodwill_019e219f-7715-7f91-ade3-6d37a6dadf3d" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_IntangibleAssetsNetExcludingGoodwill"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IntangibleAssetsGrossExcludingGoodwill_019e219f-7715-7009-afd5-1565e71cf3a8" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_IntangibleAssetsGrossExcludingGoodwill"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_IntangibleAssetsNetExcludingGoodwill_019e219f-7715-7f91-ade3-6d37a6dadf3d" xlink:to="loc_us-gaap_IntangibleAssetsGrossExcludingGoodwill_019e219f-7715-7009-afd5-1565e71cf3a8" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAccumulatedAmortization_019e219f-7715-7e21-93ad-36fe21c74dbc" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_FiniteLivedIntangibleAssetsAccumulatedAmortization"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_IntangibleAssetsNetExcludingGoodwill_019e219f-7715-7f91-ade3-6d37a6dadf3d" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsAccumulatedAmortization_019e219f-7715-7e21-93ad-36fe21c74dbc" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.cleanharbors.com/role/GOODWILLANDOTHERINTANGIBLEASSETSExpectedFutureAmortizationDetails" xlink:type="simple" xlink:href="clh-20260630.xsd#GOODWILLANDOTHERINTANGIBLEASSETSExpectedFutureAmortizationDetails"/>
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/GOODWILLANDOTHERINTANGIBLEASSETSExpectedFutureAmortizationDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsNet_019e219f-7715-7509-8318-194241e85f95" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_FiniteLivedIntangibleAssetsNet"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFour_019e219f-7715-7155-b490-c0e3dd868b99" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFour"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsNet_019e219f-7715-7509-8318-194241e85f95" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFour_019e219f-7715-7155-b490-c0e3dd868b99" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearTwo_019e219f-7715-7a69-92be-a083e9633964" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearTwo"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsNet_019e219f-7715-7509-8318-194241e85f95" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearTwo_019e219f-7715-7a69-92be-a083e9633964" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearThree_019e219f-7715-7a13-a558-2db717a79e0e" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearThree"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsNet_019e219f-7715-7509-8318-194241e85f95" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearThree_019e219f-7715-7a13-a558-2db717a79e0e" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_clh_FiniteLivedIntangibleAssetExpectedAmortizationAfterYearFour_019e219f-7715-727b-a8cc-8fa8c9b3e075" xlink:href="clh-20260630.xsd#clh_FiniteLivedIntangibleAssetExpectedAmortizationAfterYearFour"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsNet_019e219f-7715-7509-8318-194241e85f95" xlink:to="loc_clh_FiniteLivedIntangibleAssetExpectedAmortizationAfterYearFour_019e219f-7715-727b-a8cc-8fa8c9b3e075" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseNextTwelveMonths_019e219f-7715-71be-ad41-9a1ef331b59a" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseNextTwelveMonths"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsNet_019e219f-7715-7509-8318-194241e85f95" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseNextTwelveMonths_019e219f-7715-71be-ad41-9a1ef331b59a" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseRemainderOfFiscalYear_019e219f-7715-7a0a-aecc-b481bd49d694" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseRemainderOfFiscalYear"/>
    <link:calculationArc order="6" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsNet_019e219f-7715-7509-8318-194241e85f95" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseRemainderOfFiscalYear_019e219f-7715-7a0a-aecc-b481bd49d694" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.cleanharbors.com/role/ACCRUEDEXPENSESANDOTHERCURRENTLIABILITIESDetails" xlink:type="simple" xlink:href="clh-20260630.xsd#ACCRUEDEXPENSESANDOTHERCURRENTLIABILITIESDetails"/>
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/ACCRUEDEXPENSESANDOTHERCURRENTLIABILITIESDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccruedLiabilitiesCurrent_019e219f-7715-7c74-8111-c5ea628e48f9" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_AccruedLiabilitiesCurrent"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccruedInsuranceCurrent_019e219f-7715-7e74-872a-5ddc40357b98" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_AccruedInsuranceCurrent"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_AccruedLiabilitiesCurrent_019e219f-7715-7c74-8111-c5ea628e48f9" xlink:to="loc_us-gaap_AccruedInsuranceCurrent_019e219f-7715-7e74-872a-5ddc40357b98" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestPayableCurrent_019e219f-7715-7b8c-a3c4-5580afe4d787" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_InterestPayableCurrent"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_AccruedLiabilitiesCurrent_019e219f-7715-7c74-8111-c5ea628e48f9" xlink:to="loc_us-gaap_InterestPayableCurrent_019e219f-7715-7b8c-a3c4-5580afe4d787" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EmployeeRelatedLiabilitiesCurrent_019e219f-7715-7328-9d1e-e3af58a97ec7" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_EmployeeRelatedLiabilitiesCurrent"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_AccruedLiabilitiesCurrent_019e219f-7715-7c74-8111-c5ea628e48f9" xlink:to="loc_us-gaap_EmployeeRelatedLiabilitiesCurrent_019e219f-7715-7328-9d1e-e3af58a97ec7" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_TaxesPayableCurrent_019e219f-7715-7875-aaca-6629b8b985eb" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_TaxesPayableCurrent"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_AccruedLiabilitiesCurrent_019e219f-7715-7c74-8111-c5ea628e48f9" xlink:to="loc_us-gaap_TaxesPayableCurrent_019e219f-7715-7875-aaca-6629b8b985eb" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherAccruedLiabilitiesCurrent_019e219f-7715-79ef-9edc-fa267e461072" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_OtherAccruedLiabilitiesCurrent"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_AccruedLiabilitiesCurrent_019e219f-7715-7c74-8111-c5ea628e48f9" xlink:to="loc_us-gaap_OtherAccruedLiabilitiesCurrent_019e219f-7715-79ef-9edc-fa267e461072" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.cleanharbors.com/role/FINANCINGARRANGEMENTSScheduleofFinancingArrangementsDetails" xlink:type="simple" xlink:href="clh-20260630.xsd#FINANCINGARRANGEMENTSScheduleofFinancingArrangementsDetails"/>
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/FINANCINGARRANGEMENTSScheduleofFinancingArrangementsDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongTermDebtNoncurrent_019e219f-7715-74d9-b64e-896f342d187a" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_LongTermDebtNoncurrent"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentCarryingAmount_019e219f-7715-71ec-8999-24964dda17f9" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DebtInstrumentCarryingAmount"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_LongTermDebtNoncurrent_019e219f-7715-74d9-b64e-896f342d187a" xlink:to="loc_us-gaap_DebtInstrumentCarryingAmount_019e219f-7715-71ec-8999-24964dda17f9" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentUnamortizedDiscountPremiumAndDebtIssuanceCostsNet_019e219f-7715-7609-b02c-286414efec4b" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DebtInstrumentUnamortizedDiscountPremiumAndDebtIssuanceCostsNet"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_LongTermDebtNoncurrent_019e219f-7715-74d9-b64e-896f342d187a" xlink:to="loc_us-gaap_DebtInstrumentUnamortizedDiscountPremiumAndDebtIssuanceCostsNet_019e219f-7715-7609-b02c-286414efec4b" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.cleanharbors.com/role/EARNINGSPERSHAREReconciliationofBasicandDilutedEarningsPerShareComputationsDetails" xlink:type="simple" xlink:href="clh-20260630.xsd#EARNINGSPERSHAREReconciliationofBasicandDilutedEarningsPerShareComputationsDetails"/>
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/EARNINGSPERSHAREReconciliationofBasicandDilutedEarningsPerShareComputationsDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding_019e219f-7715-74f5-b602-2e37a0b19e17" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_WeightedAverageNumberOfSharesOutstandingBasic_019e219f-7715-78b0-a5c8-7b1f12ebd440" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_WeightedAverageNumberOfSharesOutstandingBasic"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding_019e219f-7715-74f5-b602-2e37a0b19e17" xlink:to="loc_us-gaap_WeightedAverageNumberOfSharesOutstandingBasic_019e219f-7715-78b0-a5c8-7b1f12ebd440" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncrementalCommonSharesAttributableToShareBasedPaymentArrangements_019e219f-7715-7aeb-a605-5fbc84fb074c" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_IncrementalCommonSharesAttributableToShareBasedPaymentArrangements"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding_019e219f-7715-74f5-b602-2e37a0b19e17" xlink:to="loc_us-gaap_IncrementalCommonSharesAttributableToShareBasedPaymentArrangements_019e219f-7715-7aeb-a605-5fbc84fb074c" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.cleanharbors.com/role/ACCUMULATEDOTHERCOMPREHENSIVELOSSChangesinAccumulatedOtherComprehensiveLossbyComponentDetails" xlink:type="simple" xlink:href="clh-20260630.xsd#ACCUMULATEDOTHERCOMPREHENSIVELOSSChangesinAccumulatedOtherComprehensiveLossbyComponentDetails"/>
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/ACCUMULATEDOTHERCOMPREHENSIVELOSSChangesinAccumulatedOtherComprehensiveLossbyComponentDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent_019e219f-7715-75eb-8ee6-8996f094e8d9" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OciBeforeReclassificationsBeforeTaxAttributableToParent_019e219f-7715-7d97-8927-b0c7de2ed00a" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_OciBeforeReclassificationsBeforeTaxAttributableToParent"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent_019e219f-7715-75eb-8ee6-8996f094e8d9" xlink:to="loc_us-gaap_OciBeforeReclassificationsBeforeTaxAttributableToParent_019e219f-7715-7d97-8927-b0c7de2ed00a" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossTaxPortionAttributableToParent1_019e219f-7715-7541-b44d-6a1d87a145fc" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_OtherComprehensiveIncomeLossTaxPortionAttributableToParent1"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent_019e219f-7715-75eb-8ee6-8996f094e8d9" xlink:to="loc_us-gaap_OtherComprehensiveIncomeLossTaxPortionAttributableToParent1_019e219f-7715-7541-b44d-6a1d87a145fc" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ReclassificationFromAociCurrentPeriodBeforeTaxAttributableToParent_019e219f-7715-73cf-8ea2-358d254de0c3" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ReclassificationFromAociCurrentPeriodBeforeTaxAttributableToParent"/>
    <link:calculationArc order="3" weight="-1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent_019e219f-7715-75eb-8ee6-8996f094e8d9" xlink:to="loc_us-gaap_ReclassificationFromAociCurrentPeriodBeforeTaxAttributableToParent_019e219f-7715-73cf-8ea2-358d254de0c3" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.cleanharbors.com/role/COMMITMENTSANDCONTINGENCIESDetails" xlink:type="simple" xlink:href="clh-20260630.xsd#COMMITMENTSANDCONTINGENCIESDetails"/>
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/COMMITMENTSANDCONTINGENCIESDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_clh_SiteContingencyNumberOfSitesOwnedByThirdParty_019e219f-7715-7aa0-839b-bbc0bc61c609" xlink:href="clh-20260630.xsd#clh_SiteContingencyNumberOfSitesOwnedByThirdParty"/>
    <link:loc xlink:type="locator" xlink:label="loc_clh_SiteContingencyEnvironmentalRemediationExpenseSettledNumberOfSitesOwnedByThirdParty_019e219f-7715-7953-92ce-faf587d40c65" xlink:href="clh-20260630.xsd#clh_SiteContingencyEnvironmentalRemediationExpenseSettledNumberOfSitesOwnedByThirdParty"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_clh_SiteContingencyNumberOfSitesOwnedByThirdParty_019e219f-7715-7aa0-839b-bbc0bc61c609" xlink:to="loc_clh_SiteContingencyEnvironmentalRemediationExpenseSettledNumberOfSitesOwnedByThirdParty_019e219f-7715-7953-92ce-faf587d40c65" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_clh_SiteContingencyEnvironmentalRemediationExpenseNumberOfSitesOwnedByThirdParty_019e219f-7715-7f5a-8765-317b2047931b" xlink:href="clh-20260630.xsd#clh_SiteContingencyEnvironmentalRemediationExpenseNumberOfSitesOwnedByThirdParty"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_clh_SiteContingencyNumberOfSitesOwnedByThirdParty_019e219f-7715-7aa0-839b-bbc0bc61c609" xlink:to="loc_clh_SiteContingencyEnvironmentalRemediationExpenseNumberOfSitesOwnedByThirdParty_019e219f-7715-7f5a-8765-317b2047931b" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_clh_SiteContingencyNotRequiringEnvironmentalRemediationExpenseNumberOfSitesOwnedByThirdParty_019e219f-7715-74e8-9275-91edee77d143" xlink:href="clh-20260630.xsd#clh_SiteContingencyNotRequiringEnvironmentalRemediationExpenseNumberOfSitesOwnedByThirdParty"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_clh_SiteContingencyNumberOfSitesOwnedByThirdParty_019e219f-7715-7aa0-839b-bbc0bc61c609" xlink:to="loc_clh_SiteContingencyNotRequiringEnvironmentalRemediationExpenseNumberOfSitesOwnedByThirdParty_019e219f-7715-74e8-9275-91edee77d143" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_clh_SiteContingencyNumberOfSites_019e219f-7715-7df2-8205-1e2f44d61d06" xlink:href="clh-20260630.xsd#clh_SiteContingencyNumberOfSites"/>
    <link:loc xlink:type="locator" xlink:label="loc_clh_SiteContingencyNumberOfSitesOwnedByEntity_019e219f-7715-7ce5-b369-c97633869ad4" xlink:href="clh-20260630.xsd#clh_SiteContingencyNumberOfSitesOwnedByEntity"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_clh_SiteContingencyNumberOfSites_019e219f-7715-7df2-8205-1e2f44d61d06" xlink:to="loc_clh_SiteContingencyNumberOfSitesOwnedByEntity_019e219f-7715-7ce5-b369-c97633869ad4" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_clh_SiteContingencyNumberOfSitesOwnedByThirdParty_019e219f-7715-733a-b584-90632b91b3af" xlink:href="clh-20260630.xsd#clh_SiteContingencyNumberOfSitesOwnedByThirdParty"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_clh_SiteContingencyNumberOfSites_019e219f-7715-7df2-8205-1e2f44d61d06" xlink:to="loc_clh_SiteContingencyNumberOfSitesOwnedByThirdParty_019e219f-7715-733a-b584-90632b91b3af" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.cleanharbors.com/role/SEGMENTREPORTINGAdjustedEBITDAandSignificantSegmentExpenseInformationDetails" xlink:type="simple" xlink:href="clh-20260630.xsd#SEGMENTREPORTINGAdjustedEBITDAandSignificantSegmentExpenseInformationDetails"/>
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/SEGMENTREPORTINGAdjustedEBITDAandSignificantSegmentExpenseInformationDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_clh_IncomeLossFromContinuingOperationsBeforeInterestTaxDepreciationAndAmortizationNet_019e219f-7715-77ab-b5cd-daa39aef38cc" xlink:href="clh-20260630.xsd#clh_IncomeLossFromContinuingOperationsBeforeInterestTaxDepreciationAndAmortizationNet"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax_019e219f-7715-781b-9702-5841a2b02bcb" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_clh_IncomeLossFromContinuingOperationsBeforeInterestTaxDepreciationAndAmortizationNet_019e219f-7715-77ab-b5cd-daa39aef38cc" xlink:to="loc_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax_019e219f-7715-781b-9702-5841a2b02bcb" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SellingGeneralAndAdministrativeExpense_019e219f-7715-7708-ac05-ae7c6617c55c" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_SellingGeneralAndAdministrativeExpense"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_clh_IncomeLossFromContinuingOperationsBeforeInterestTaxDepreciationAndAmortizationNet_019e219f-7715-77ab-b5cd-daa39aef38cc" xlink:to="loc_us-gaap_SellingGeneralAndAdministrativeExpense_019e219f-7715-7708-ac05-ae7c6617c55c" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CostOfGoodsAndServicesSold_019e219f-7715-7f89-8dc3-428849014db0" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_CostOfGoodsAndServicesSold"/>
    <link:calculationArc order="3" weight="-1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_clh_IncomeLossFromContinuingOperationsBeforeInterestTaxDepreciationAndAmortizationNet_019e219f-7715-77ab-b5cd-daa39aef38cc" xlink:to="loc_us-gaap_CostOfGoodsAndServicesSold_019e219f-7715-7f89-8dc3-428849014db0" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.cleanharbors.com/role/SEGMENTREPORTINGReconciliationtoConsolidatedStatementsofIncometoAdjustedEBITDADetails" xlink:type="simple" xlink:href="clh-20260630.xsd#SEGMENTREPORTINGReconciliationtoConsolidatedStatementsofIncometoAdjustedEBITDADetails"/>
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/SEGMENTREPORTINGReconciliationtoConsolidatedStatementsofIncometoAdjustedEBITDADetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingIncomeLoss_019e219f-7715-7d5e-aeae-65429154a190" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_OperatingIncomeLoss"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensation_019e219f-7715-797e-8b2d-c80a355b1fb4" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_ShareBasedCompensation"/>
    <link:calculationArc order="1" weight="-1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_OperatingIncomeLoss_019e219f-7715-7d5e-aeae-65429154a190" xlink:to="loc_us-gaap_ShareBasedCompensation_019e219f-7715-797e-8b2d-c80a355b1fb4" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_clh_AccretionOfEnvironmentalLiabilities_019e219f-7715-7cb6-8903-949a9de610b7" xlink:href="clh-20260630.xsd#clh_AccretionOfEnvironmentalLiabilities"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_OperatingIncomeLoss_019e219f-7715-7d5e-aeae-65429154a190" xlink:to="loc_clh_AccretionOfEnvironmentalLiabilities_019e219f-7715-7cb6-8903-949a9de610b7" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DepreciationDepletionAndAmortization_019e219f-7715-7d72-beb0-1f3063f241f1" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DepreciationDepletionAndAmortization"/>
    <link:calculationArc order="3" weight="-1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_OperatingIncomeLoss_019e219f-7715-7d5e-aeae-65429154a190" xlink:to="loc_us-gaap_DepreciationDepletionAndAmortization_019e219f-7715-7d72-beb0-1f3063f241f1" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_clh_CorporateCosts_019e219f-7715-7901-9379-c0932b3638ee" xlink:href="clh-20260630.xsd#clh_CorporateCosts"/>
    <link:calculationArc order="4" weight="-1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_OperatingIncomeLoss_019e219f-7715-7d5e-aeae-65429154a190" xlink:to="loc_clh_CorporateCosts_019e219f-7715-7901-9379-c0932b3638ee" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_clh_IncomeLossFromContinuingOperationsBeforeInterestTaxDepreciationAndAmortizationNet_019e219f-7715-7f56-ba93-24e65e5d2054" xlink:href="clh-20260630.xsd#clh_IncomeLossFromContinuingOperationsBeforeInterestTaxDepreciationAndAmortizationNet"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_us-gaap_OperatingIncomeLoss_019e219f-7715-7d5e-aeae-65429154a190" xlink:to="loc_clh_IncomeLossFromContinuingOperationsBeforeInterestTaxDepreciationAndAmortizationNet_019e219f-7715-7f56-ba93-24e65e5d2054" xlink:type="arc"/>
  </link:calculationLink>
</link:linkbase>
