

<!--XBRL Document Created with Wdesk from Workiva-->
<!-- -->
<link:linkbase xsi:schemaLocation="http://www.xbrl.org/2003/linkbase http://www.xbrl.org/2003/xbrl-linkbase-2003-12-31.xsd" xmlns:link="http://www.xbrl.org/2003/linkbase" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
  <link:roleRef roleURI="http://www.cleanharbors.com/role/AccruedExpenses" xlink:href="clh-20171231.xsd#AccruedExpenses" xlink:type="simple" />
  <link:roleRef roleURI="http://www.cleanharbors.com/role/AccruedExpensesDetails" xlink:href="clh-20171231.xsd#AccruedExpensesDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.cleanharbors.com/role/AccruedExpensesTables" xlink:href="clh-20171231.xsd#AccruedExpensesTables" xlink:type="simple" />
  <link:roleRef roleURI="http://www.cleanharbors.com/role/AccumulatedOtherComprehensiveLoss" xlink:href="clh-20171231.xsd#AccumulatedOtherComprehensiveLoss" xlink:type="simple" />
  <link:roleRef roleURI="http://www.cleanharbors.com/role/AccumulatedOtherComprehensiveLossComponentsOfAociDetails" xlink:href="clh-20171231.xsd#AccumulatedOtherComprehensiveLossComponentsOfAociDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.cleanharbors.com/role/AccumulatedOtherComprehensiveLossReclassificationOutOfAociDetails" xlink:href="clh-20171231.xsd#AccumulatedOtherComprehensiveLossReclassificationOutOfAociDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.cleanharbors.com/role/AccumulatedOtherComprehensiveLossTables" xlink:href="clh-20171231.xsd#AccumulatedOtherComprehensiveLossTables" xlink:type="simple" />
  <link:roleRef roleURI="http://www.cleanharbors.com/role/BusinessCombinations" xlink:href="clh-20171231.xsd#BusinessCombinations" xlink:type="simple" />
  <link:roleRef roleURI="http://www.cleanharbors.com/role/BusinessCombinations2015AcquisitionsDetails" xlink:href="clh-20171231.xsd#BusinessCombinations2015AcquisitionsDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.cleanharbors.com/role/BusinessCombinations2015AcquisitionsNarrativeDetails" xlink:href="clh-20171231.xsd#BusinessCombinations2015AcquisitionsNarrativeDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.cleanharbors.com/role/BusinessCombinations2016AcquisitionsDetails" xlink:href="clh-20171231.xsd#BusinessCombinations2016AcquisitionsDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.cleanharbors.com/role/BusinessCombinations2016AcquisitionsNarrativeDetails" xlink:href="clh-20171231.xsd#BusinessCombinations2016AcquisitionsNarrativeDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.cleanharbors.com/role/BusinessCombinations2017AcquisitionsDetails" xlink:href="clh-20171231.xsd#BusinessCombinations2017AcquisitionsDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.cleanharbors.com/role/BusinessCombinationsTables" xlink:href="clh-20171231.xsd#BusinessCombinationsTables" xlink:type="simple" />
  <link:roleRef roleURI="http://www.cleanharbors.com/role/ClosureAndPostClosureLiabilities" xlink:href="clh-20171231.xsd#ClosureAndPostClosureLiabilities" xlink:type="simple" />
  <link:roleRef roleURI="http://www.cleanharbors.com/role/ClosureAndPostClosureLiabilitiesAnticipatedPaymentsDetails" xlink:href="clh-20171231.xsd#ClosureAndPostClosureLiabilitiesAnticipatedPaymentsDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.cleanharbors.com/role/ClosureAndPostClosureLiabilitiesChangesInPostClosureLiabilitiesDetails" xlink:href="clh-20171231.xsd#ClosureAndPostClosureLiabilitiesChangesInPostClosureLiabilitiesDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.cleanharbors.com/role/ClosureAndPostClosureLiabilitiesTables" xlink:href="clh-20171231.xsd#ClosureAndPostClosureLiabilitiesTables" xlink:type="simple" />
  <link:roleRef roleURI="http://www.cleanharbors.com/role/CommitmentsAndContingencies" xlink:href="clh-20171231.xsd#CommitmentsAndContingencies" xlink:type="simple" />
  <link:roleRef roleURI="http://www.cleanharbors.com/role/CommitmentsAndContingenciesFederalStateAndProvincialEnforcementActionsDetails" xlink:href="clh-20171231.xsd#CommitmentsAndContingenciesFederalStateAndProvincialEnforcementActionsDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.cleanharbors.com/role/CommitmentsAndContingenciesLeasesDetails" xlink:href="clh-20171231.xsd#CommitmentsAndContingenciesLeasesDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.cleanharbors.com/role/CommitmentsAndContingenciesLegalAndAdministrativeProceedingsDetails" xlink:href="clh-20171231.xsd#CommitmentsAndContingenciesLegalAndAdministrativeProceedingsDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.cleanharbors.com/role/CommitmentsAndContingenciesOtherContingenciesDetails" xlink:href="clh-20171231.xsd#CommitmentsAndContingenciesOtherContingenciesDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.cleanharbors.com/role/CommitmentsAndContingenciesOtherContingenciesDetailsCalc2" xlink:href="clh-20171231.xsd#CommitmentsAndContingenciesOtherContingenciesDetailsCalc2" xlink:type="simple" />
  <link:roleRef roleURI="http://www.cleanharbors.com/role/CommitmentsAndContingenciesSuperfundProceedingsDetails" xlink:href="clh-20171231.xsd#CommitmentsAndContingenciesSuperfundProceedingsDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.cleanharbors.com/role/CommitmentsAndContingenciesTables" xlink:href="clh-20171231.xsd#CommitmentsAndContingenciesTables" xlink:type="simple" />
  <link:roleRef roleURI="http://www.cleanharbors.com/role/ConsolidatedBalanceSheets" xlink:href="clh-20171231.xsd#ConsolidatedBalanceSheets" xlink:type="simple" />
  <link:roleRef roleURI="http://www.cleanharbors.com/role/ConsolidatedBalanceSheetsParenthetical" xlink:href="clh-20171231.xsd#ConsolidatedBalanceSheetsParenthetical" xlink:type="simple" />
  <link:roleRef roleURI="http://www.cleanharbors.com/role/ConsolidatedStatementsOfCashFlows" xlink:href="clh-20171231.xsd#ConsolidatedStatementsOfCashFlows" xlink:type="simple" />
  <link:roleRef roleURI="http://www.cleanharbors.com/role/ConsolidatedStatementsOfComprehensiveIncomeLoss" xlink:href="clh-20171231.xsd#ConsolidatedStatementsOfComprehensiveIncomeLoss" xlink:type="simple" />
  <link:roleRef roleURI="http://www.cleanharbors.com/role/ConsolidatedStatementsOfComprehensiveIncomeLossParenthetical" xlink:href="clh-20171231.xsd#ConsolidatedStatementsOfComprehensiveIncomeLossParenthetical" xlink:type="simple" />
  <link:roleRef roleURI="http://www.cleanharbors.com/role/ConsolidatedStatementsOfOperations" xlink:href="clh-20171231.xsd#ConsolidatedStatementsOfOperations" xlink:type="simple" />
  <link:roleRef roleURI="http://www.cleanharbors.com/role/ConsolidatedStatementsOfOperationsParenthetical" xlink:href="clh-20171231.xsd#ConsolidatedStatementsOfOperationsParenthetical" xlink:type="simple" />
  <link:roleRef roleURI="http://www.cleanharbors.com/role/ConsolidatedStatementsOfStockholdersEquity" xlink:href="clh-20171231.xsd#ConsolidatedStatementsOfStockholdersEquity" xlink:type="simple" />
  <link:roleRef roleURI="http://www.cleanharbors.com/role/ConsolidatedStatementsOfStockholdersEquityParenthetical" xlink:href="clh-20171231.xsd#ConsolidatedStatementsOfStockholdersEquityParenthetical" xlink:type="simple" />
  <link:roleRef roleURI="http://www.cleanharbors.com/role/DispositionOfBusiness" xlink:href="clh-20171231.xsd#DispositionOfBusiness" xlink:type="simple" />
  <link:roleRef roleURI="http://www.cleanharbors.com/role/DispositionOfBusiness2016DispositionDetails" xlink:href="clh-20171231.xsd#DispositionOfBusiness2016DispositionDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.cleanharbors.com/role/DispositionOfBusiness2016DispositionNarrativeDetails" xlink:href="clh-20171231.xsd#DispositionOfBusiness2016DispositionNarrativeDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.cleanharbors.com/role/DispositionOfBusiness2017DispositionNarrativeDetails" xlink:href="clh-20171231.xsd#DispositionOfBusiness2017DispositionNarrativeDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.cleanharbors.com/role/DispositionOfBusiness2017DispositionsDetails" xlink:href="clh-20171231.xsd#DispositionOfBusiness2017DispositionsDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.cleanharbors.com/role/DispositionOfBusinessDispositionOfBusinessIncomeLossAttributableToTransformerServicesDetails" xlink:href="clh-20171231.xsd#DispositionOfBusinessDispositionOfBusinessIncomeLossAttributableToTransformerServicesDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.cleanharbors.com/role/DispositionOfBusinessIncomeLossAttributableToCatalystServicesDetails" xlink:href="clh-20171231.xsd#DispositionOfBusinessIncomeLossAttributableToCatalystServicesDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.cleanharbors.com/role/DispositionOfBusinessTables" xlink:href="clh-20171231.xsd#DispositionOfBusinessTables" xlink:type="simple" />
  <link:roleRef roleURI="http://www.cleanharbors.com/role/DocumentAndEntityInformation" xlink:href="clh-20171231.xsd#DocumentAndEntityInformation" xlink:type="simple" />
  <link:roleRef roleURI="http://www.cleanharbors.com/role/EarningsLossPerShare" xlink:href="clh-20171231.xsd#EarningsLossPerShare" xlink:type="simple" />
  <link:roleRef roleURI="http://www.cleanharbors.com/role/EarningsLossPerShareAntiDilutiveSecuritiesDetails" xlink:href="clh-20171231.xsd#EarningsLossPerShareAntiDilutiveSecuritiesDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.cleanharbors.com/role/EarningsLossPerShareReconciliationOfBasicAndDilutedEarningsPerShareComputationsDetails" xlink:href="clh-20171231.xsd#EarningsLossPerShareReconciliationOfBasicAndDilutedEarningsPerShareComputationsDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.cleanharbors.com/role/EarningsLossPerShareTables" xlink:href="clh-20171231.xsd#EarningsLossPerShareTables" xlink:type="simple" />
  <link:roleRef roleURI="http://www.cleanharbors.com/role/FinancingArrangements" xlink:href="clh-20171231.xsd#FinancingArrangements" xlink:type="simple" />
  <link:roleRef roleURI="http://www.cleanharbors.com/role/FinancingArrangementsNarrativeDetails" xlink:href="clh-20171231.xsd#FinancingArrangementsNarrativeDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.cleanharbors.com/role/FinancingArrangementsScheduleOfRedemptionPricesDetails" xlink:href="clh-20171231.xsd#FinancingArrangementsScheduleOfRedemptionPricesDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.cleanharbors.com/role/FinancingArrangementsSummaryOfFinancingArrangementsDetails" xlink:href="clh-20171231.xsd#FinancingArrangementsSummaryOfFinancingArrangementsDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.cleanharbors.com/role/FinancingArrangementsTables" xlink:href="clh-20171231.xsd#FinancingArrangementsTables" xlink:type="simple" />
  <link:roleRef roleURI="http://www.cleanharbors.com/role/GoodwillAndOtherIntangibleAssets" xlink:href="clh-20171231.xsd#GoodwillAndOtherIntangibleAssets" xlink:type="simple" />
  <link:roleRef roleURI="http://www.cleanharbors.com/role/GoodwillAndOtherIntangibleAssetsChangesToGoodwillDetails" xlink:href="clh-20171231.xsd#GoodwillAndOtherIntangibleAssetsChangesToGoodwillDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.cleanharbors.com/role/GoodwillAndOtherIntangibleAssetsExpectedAmortizationDetails" xlink:href="clh-20171231.xsd#GoodwillAndOtherIntangibleAssetsExpectedAmortizationDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.cleanharbors.com/role/GoodwillAndOtherIntangibleAssetsFiniteLivedAndIndefiniteLivedIntangibleAssetsDetails" xlink:href="clh-20171231.xsd#GoodwillAndOtherIntangibleAssetsFiniteLivedAndIndefiniteLivedIntangibleAssetsDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.cleanharbors.com/role/GoodwillAndOtherIntangibleAssetsNarrativeDetails" xlink:href="clh-20171231.xsd#GoodwillAndOtherIntangibleAssetsNarrativeDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.cleanharbors.com/role/GoodwillAndOtherIntangibleAssetsTables" xlink:href="clh-20171231.xsd#GoodwillAndOtherIntangibleAssetsTables" xlink:type="simple" />
  <link:roleRef roleURI="http://www.cleanharbors.com/role/GuarantorAndNonGuarantorSubsidiaries" xlink:href="clh-20171231.xsd#GuarantorAndNonGuarantorSubsidiaries" xlink:type="simple" />
  <link:roleRef roleURI="http://www.cleanharbors.com/role/GuarantorAndNonGuarantorSubsidiariesBalanceSheetDetails" xlink:href="clh-20171231.xsd#GuarantorAndNonGuarantorSubsidiariesBalanceSheetDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.cleanharbors.com/role/GuarantorAndNonGuarantorSubsidiariesCashFlowsDetails" xlink:href="clh-20171231.xsd#GuarantorAndNonGuarantorSubsidiariesCashFlowsDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.cleanharbors.com/role/GuarantorAndNonGuarantorSubsidiariesIncomeStatementDetails" xlink:href="clh-20171231.xsd#GuarantorAndNonGuarantorSubsidiariesIncomeStatementDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.cleanharbors.com/role/GuarantorAndNonGuarantorSubsidiariesTables" xlink:href="clh-20171231.xsd#GuarantorAndNonGuarantorSubsidiariesTables" xlink:type="simple" />
  <link:roleRef roleURI="http://www.cleanharbors.com/role/IncomeTaxes" xlink:href="clh-20171231.xsd#IncomeTaxes" xlink:type="simple" />
  <link:roleRef roleURI="http://www.cleanharbors.com/role/IncomeTaxesAdditionalInformationDetails" xlink:href="clh-20171231.xsd#IncomeTaxesAdditionalInformationDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.cleanharbors.com/role/IncomeTaxesDeferredTaxAssetsAndLiabilitiesDetails" xlink:href="clh-20171231.xsd#IncomeTaxesDeferredTaxAssetsAndLiabilitiesDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.cleanharbors.com/role/IncomeTaxesProvisionForTaxExpenseDetails" xlink:href="clh-20171231.xsd#IncomeTaxesProvisionForTaxExpenseDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.cleanharbors.com/role/IncomeTaxesProvisionForTaxExpenseDetailsCalc2" xlink:href="clh-20171231.xsd#IncomeTaxesProvisionForTaxExpenseDetailsCalc2" xlink:type="simple" />
  <link:roleRef roleURI="http://www.cleanharbors.com/role/IncomeTaxesTables" xlink:href="clh-20171231.xsd#IncomeTaxesTables" xlink:type="simple" />
  <link:roleRef roleURI="http://www.cleanharbors.com/role/IncomeTaxesUnrecognizedTaxBenefitsDetails" xlink:href="clh-20171231.xsd#IncomeTaxesUnrecognizedTaxBenefitsDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.cleanharbors.com/role/InventoriesAndSupplies" xlink:href="clh-20171231.xsd#InventoriesAndSupplies" xlink:type="simple" />
  <link:roleRef roleURI="http://www.cleanharbors.com/role/InventoriesAndSuppliesDetails" xlink:href="clh-20171231.xsd#InventoriesAndSuppliesDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.cleanharbors.com/role/InventoriesAndSuppliesTables" xlink:href="clh-20171231.xsd#InventoriesAndSuppliesTables" xlink:type="simple" />
  <link:roleRef roleURI="http://www.cleanharbors.com/role/Operations" xlink:href="clh-20171231.xsd#Operations" xlink:type="simple" />
  <link:roleRef roleURI="http://www.cleanharbors.com/role/PropertyPlantAndEquipment" xlink:href="clh-20171231.xsd#PropertyPlantAndEquipment" xlink:type="simple" />
  <link:roleRef roleURI="http://www.cleanharbors.com/role/PropertyPlantAndEquipmentDetails" xlink:href="clh-20171231.xsd#PropertyPlantAndEquipmentDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.cleanharbors.com/role/PropertyPlantAndEquipmentTables" xlink:href="clh-20171231.xsd#PropertyPlantAndEquipmentTables" xlink:type="simple" />
  <link:roleRef roleURI="http://www.cleanharbors.com/role/QuarterlyDataUnaudited" xlink:href="clh-20171231.xsd#QuarterlyDataUnaudited" xlink:type="simple" />
  <link:roleRef roleURI="http://www.cleanharbors.com/role/QuarterlyDataUnauditedDetails" xlink:href="clh-20171231.xsd#QuarterlyDataUnauditedDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.cleanharbors.com/role/QuarterlyDataUnauditedTables" xlink:href="clh-20171231.xsd#QuarterlyDataUnauditedTables" xlink:type="simple" />
  <link:roleRef roleURI="http://www.cleanharbors.com/role/RemedialLiabilities" xlink:href="clh-20171231.xsd#RemedialLiabilities" xlink:type="simple" />
  <link:roleRef roleURI="http://www.cleanharbors.com/role/RemedialLiabilitiesAdditionalInformationDetails" xlink:href="clh-20171231.xsd#RemedialLiabilitiesAdditionalInformationDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.cleanharbors.com/role/RemedialLiabilitiesAnticipatedPaymentsDetails" xlink:href="clh-20171231.xsd#RemedialLiabilitiesAnticipatedPaymentsDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.cleanharbors.com/role/RemedialLiabilitiesChangesInRemedialLiabilitiesDetails" xlink:href="clh-20171231.xsd#RemedialLiabilitiesChangesInRemedialLiabilitiesDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.cleanharbors.com/role/RemedialLiabilitiesEstimatesDetails" xlink:href="clh-20171231.xsd#RemedialLiabilitiesEstimatesDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.cleanharbors.com/role/RemedialLiabilitiesTables" xlink:href="clh-20171231.xsd#RemedialLiabilitiesTables" xlink:type="simple" />
  <link:roleRef roleURI="http://www.cleanharbors.com/role/ScheduleIiValuationAndQualifyingAccounts" xlink:href="clh-20171231.xsd#ScheduleIiValuationAndQualifyingAccounts" xlink:type="simple" />
  <link:roleRef roleURI="http://www.cleanharbors.com/role/ScheduleIiValuationAndQualifyingAccountsDetails" xlink:href="clh-20171231.xsd#ScheduleIiValuationAndQualifyingAccountsDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.cleanharbors.com/role/SegmentReporting" xlink:href="clh-20171231.xsd#SegmentReporting" xlink:type="simple" />
  <link:roleRef roleURI="http://www.cleanharbors.com/role/SegmentReportingSegmentAdditionalInformationDetails" xlink:href="clh-20171231.xsd#SegmentReportingSegmentAdditionalInformationDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.cleanharbors.com/role/SegmentReportingSegmentInformationRevenuesEbitaAndReconciliationToConsolidatedStatementOfOperationsDetails" xlink:href="clh-20171231.xsd#SegmentReportingSegmentInformationRevenuesEbitaAndReconciliationToConsolidatedStatementOfOperationsDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.cleanharbors.com/role/SegmentReportingTables" xlink:href="clh-20171231.xsd#SegmentReportingTables" xlink:type="simple" />
  <link:roleRef roleURI="http://www.cleanharbors.com/role/SignificantAccountingPolicies" xlink:href="clh-20171231.xsd#SignificantAccountingPolicies" xlink:type="simple" />
  <link:roleRef roleURI="http://www.cleanharbors.com/role/SignificantAccountingPoliciesAdvertisingExpenseDetails" xlink:href="clh-20171231.xsd#SignificantAccountingPoliciesAdvertisingExpenseDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.cleanharbors.com/role/SignificantAccountingPoliciesAvailableForSaleInvestmentsDetails" xlink:href="clh-20171231.xsd#SignificantAccountingPoliciesAvailableForSaleInvestmentsDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.cleanharbors.com/role/SignificantAccountingPoliciesCashCashEquivalentsAndUncashedChecksDetails" xlink:href="clh-20171231.xsd#SignificantAccountingPoliciesCashCashEquivalentsAndUncashedChecksDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.cleanharbors.com/role/SignificantAccountingPoliciesCreditConcentrationDetails" xlink:href="clh-20171231.xsd#SignificantAccountingPoliciesCreditConcentrationDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.cleanharbors.com/role/SignificantAccountingPoliciesFinancialAssetsMeasuredOnRecurringBasisDetails" xlink:href="clh-20171231.xsd#SignificantAccountingPoliciesFinancialAssetsMeasuredOnRecurringBasisDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.cleanharbors.com/role/SignificantAccountingPoliciesGoodwillAndIntangibleAssetsDetails" xlink:href="clh-20171231.xsd#SignificantAccountingPoliciesGoodwillAndIntangibleAssetsDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.cleanharbors.com/role/SignificantAccountingPoliciesLandfillAccountingDetails" xlink:href="clh-20171231.xsd#SignificantAccountingPoliciesLandfillAccountingDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.cleanharbors.com/role/SignificantAccountingPoliciesMarketableSecuritiesByContractualMaturityDetails" xlink:href="clh-20171231.xsd#SignificantAccountingPoliciesMarketableSecuritiesByContractualMaturityDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.cleanharbors.com/role/SignificantAccountingPoliciesPolicies" xlink:href="clh-20171231.xsd#SignificantAccountingPoliciesPolicies" xlink:type="simple" />
  <link:roleRef roleURI="http://www.cleanharbors.com/role/SignificantAccountingPoliciesPropertyPlantAndEquipmentDetails" xlink:href="clh-20171231.xsd#SignificantAccountingPoliciesPropertyPlantAndEquipmentDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.cleanharbors.com/role/SignificantAccountingPoliciesRecentlyAccountingPronouncementsDetails" xlink:href="clh-20171231.xsd#SignificantAccountingPoliciesRecentlyAccountingPronouncementsDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.cleanharbors.com/role/SignificantAccountingPoliciesRemedialLiabilitiesDetails" xlink:href="clh-20171231.xsd#SignificantAccountingPoliciesRemedialLiabilitiesDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.cleanharbors.com/role/SignificantAccountingPoliciesRevenueRecognitionAndDeferredRevenueDetails" xlink:href="clh-20171231.xsd#SignificantAccountingPoliciesRevenueRecognitionAndDeferredRevenueDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.cleanharbors.com/role/SignificantAccountingPoliciesTables" xlink:href="clh-20171231.xsd#SignificantAccountingPoliciesTables" xlink:type="simple" />
  <link:roleRef roleURI="http://www.cleanharbors.com/role/StockBasedCompensationAndEmployeeBenefitPlans" xlink:href="clh-20171231.xsd#StockBasedCompensationAndEmployeeBenefitPlans" xlink:type="simple" />
  <link:roleRef roleURI="http://www.cleanharbors.com/role/StockBasedCompensationAndEmployeeBenefitPlansEmployeeBenefitPlansDetails" xlink:href="clh-20171231.xsd#StockBasedCompensationAndEmployeeBenefitPlansEmployeeBenefitPlansDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.cleanharbors.com/role/StockBasedCompensationAndEmployeeBenefitPlansPerformanceStockAwardsDetails" xlink:href="clh-20171231.xsd#StockBasedCompensationAndEmployeeBenefitPlansPerformanceStockAwardsDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.cleanharbors.com/role/StockBasedCompensationAndEmployeeBenefitPlansRestrictedStockAwardsDetails" xlink:href="clh-20171231.xsd#StockBasedCompensationAndEmployeeBenefitPlansRestrictedStockAwardsDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.cleanharbors.com/role/StockBasedCompensationAndEmployeeBenefitPlansStockBasedCompensationDetails" xlink:href="clh-20171231.xsd#StockBasedCompensationAndEmployeeBenefitPlansStockBasedCompensationDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.cleanharbors.com/role/StockBasedCompensationAndEmployeeBenefitPlansTables" xlink:href="clh-20171231.xsd#StockBasedCompensationAndEmployeeBenefitPlansTables" xlink:type="simple" />
  <link:roleRef roleURI="http://www.cleanharbors.com/role/StockholdersEquity" xlink:href="clh-20171231.xsd#StockholdersEquity" xlink:type="simple" />
  <link:roleRef roleURI="http://www.cleanharbors.com/role/StockholdersEquityDetails" xlink:href="clh-20171231.xsd#StockholdersEquityDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.cleanharbors.com/role/SubsequentEvents" xlink:href="clh-20171231.xsd#SubsequentEvents" xlink:type="simple" />
  <link:roleRef roleURI="http://www.cleanharbors.com/role/SubsequentEventsSubsequentEventsDetails" xlink:href="clh-20171231.xsd#SubsequentEventsSubsequentEventsDetails" xlink:type="simple" />
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/AccruedExpenses" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/AccruedExpensesDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_AccruedLiabilitiesCurrent" xlink:label="loc_us-gaap_AccruedLiabilitiesCurrent_3fe8f96b-142b-97b1-3b39-b8d22cd10e98" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_AccruedInsuranceCurrent" xlink:label="loc_us-gaap_AccruedInsuranceCurrent_33c9a379-61ce-ebac-1aab-df972478a75d" xlink:type="locator" />
    <link:calculationArc order="1" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AccruedLiabilitiesCurrent_3fe8f96b-142b-97b1-3b39-b8d22cd10e98" xlink:to="loc_us-gaap_AccruedInsuranceCurrent_33c9a379-61ce-ebac-1aab-df972478a75d" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_InterestPayableCurrent" xlink:label="loc_us-gaap_InterestPayableCurrent_f399ab19-6853-cf94-a0cf-c511e9e00641" xlink:type="locator" />
    <link:calculationArc order="2" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AccruedLiabilitiesCurrent_3fe8f96b-142b-97b1-3b39-b8d22cd10e98" xlink:to="loc_us-gaap_InterestPayableCurrent_f399ab19-6853-cf94-a0cf-c511e9e00641" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_EmployeeRelatedLiabilitiesCurrent" xlink:label="loc_us-gaap_EmployeeRelatedLiabilitiesCurrent_cf9ed09f-3dd1-4a4b-d3fc-3b0db18c1b40" xlink:type="locator" />
    <link:calculationArc order="3" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AccruedLiabilitiesCurrent_3fe8f96b-142b-97b1-3b39-b8d22cd10e98" xlink:to="loc_us-gaap_EmployeeRelatedLiabilitiesCurrent_cf9ed09f-3dd1-4a4b-d3fc-3b0db18c1b40" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_TaxesPayableCurrent" xlink:label="loc_us-gaap_TaxesPayableCurrent_8544ed0a-bea0-b1fa-ce65-66a1927d2672" xlink:type="locator" />
    <link:calculationArc order="4" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AccruedLiabilitiesCurrent_3fe8f96b-142b-97b1-3b39-b8d22cd10e98" xlink:to="loc_us-gaap_TaxesPayableCurrent_8544ed0a-bea0-b1fa-ce65-66a1927d2672" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_OtherAccruedLiabilitiesCurrent" xlink:label="loc_us-gaap_OtherAccruedLiabilitiesCurrent_00b000cf-7f1d-4891-7244-daf9f6335db0" xlink:type="locator" />
    <link:calculationArc order="5" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AccruedLiabilitiesCurrent_3fe8f96b-142b-97b1-3b39-b8d22cd10e98" xlink:to="loc_us-gaap_OtherAccruedLiabilitiesCurrent_00b000cf-7f1d-4891-7244-daf9f6335db0" xlink:type="arc" />
  </link:calculationLink>
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/AccruedExpensesTables" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/AccumulatedOtherComprehensiveLoss" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/AccumulatedOtherComprehensiveLossComponentsOfAociDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossNetOfTax" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTax_2a6e77d2-a694-61f8-1c68-085fd849c780" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossBeforeReclassificationsNetOfTax" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossBeforeReclassificationsNetOfTax_80870f71-876e-eaaa-f0a4-8338d8e9798b" xlink:type="locator" />
    <link:calculationArc order="1" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTax_2a6e77d2-a694-61f8-1c68-085fd849c780" xlink:to="loc_us-gaap_OtherComprehensiveIncomeLossBeforeReclassificationsNetOfTax_80870f71-876e-eaaa-f0a4-8338d8e9798b" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ReclassificationFromAccumulatedOtherComprehensiveIncomeCurrentPeriodNetOfTax" xlink:label="loc_us-gaap_ReclassificationFromAccumulatedOtherComprehensiveIncomeCurrentPeriodNetOfTax_c1323577-e536-9051-1401-d064e7621fd6" xlink:type="locator" />
    <link:calculationArc order="2" weight="-1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTax_2a6e77d2-a694-61f8-1c68-085fd849c780" xlink:to="loc_us-gaap_ReclassificationFromAccumulatedOtherComprehensiveIncomeCurrentPeriodNetOfTax_c1323577-e536-9051-1401-d064e7621fd6" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossTax" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossTax_fd5fd01d-ccd5-2fe2-e9ee-a9a84a842378" xlink:type="locator" />
    <link:calculationArc order="3" weight="-1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTax_2a6e77d2-a694-61f8-1c68-085fd849c780" xlink:to="loc_us-gaap_OtherComprehensiveIncomeLossTax_fd5fd01d-ccd5-2fe2-e9ee-a9a84a842378" xlink:type="arc" />
  </link:calculationLink>
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/AccumulatedOtherComprehensiveLossReclassificationOutOfAociDetails" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/AccumulatedOtherComprehensiveLossTables" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/BusinessCombinations" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/BusinessCombinations2015AcquisitionsDetails" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/BusinessCombinations2015AcquisitionsNarrativeDetails" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/BusinessCombinations2016AcquisitionsDetails" xlink:type="extended">
    <link:loc xlink:href="clh-20171231.xsd#clh_BusinessCombinationMeasurementPeriodAdjustmentGoodwillAndLiabilitiesAssumedNet" xlink:label="loc_clh_BusinessCombinationMeasurementPeriodAdjustmentGoodwillAndLiabilitiesAssumedNet_68908ac4-78a9-27f4-728f-cb24d90dff6d" xlink:type="locator" />
    <link:loc xlink:href="clh-20171231.xsd#clh_BusinessCombinationMeasurementPeriodAdjustmentsNet" xlink:label="loc_clh_BusinessCombinationMeasurementPeriodAdjustmentsNet_d817f90e-ef90-5ff7-8465-cb24d877cd62" xlink:type="locator" />
    <link:calculationArc order="1" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_clh_BusinessCombinationMeasurementPeriodAdjustmentGoodwillAndLiabilitiesAssumedNet_68908ac4-78a9-27f4-728f-cb24d90dff6d" xlink:to="loc_clh_BusinessCombinationMeasurementPeriodAdjustmentsNet_d817f90e-ef90-5ff7-8465-cb24d877cd62" xlink:type="arc" />
    <link:loc xlink:href="clh-20171231.xsd#clh_BusinessCombinationMeasurementPeriodAdjustmentsCurrentAssetsReceivables" xlink:label="loc_clh_BusinessCombinationMeasurementPeriodAdjustmentsCurrentAssetsReceivables_42742c1b-6ce7-a1a9-06a9-cb24d922e16c" xlink:type="locator" />
    <link:calculationArc order="1" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_clh_BusinessCombinationMeasurementPeriodAdjustmentsNet_d817f90e-ef90-5ff7-8465-cb24d877cd62" xlink:to="loc_clh_BusinessCombinationMeasurementPeriodAdjustmentsCurrentAssetsReceivables_42742c1b-6ce7-a1a9-06a9-cb24d922e16c" xlink:type="arc" />
    <link:loc xlink:href="clh-20171231.xsd#clh_BusinessCombinationMeasurementPeriodAdjustmentsInventory" xlink:label="loc_clh_BusinessCombinationMeasurementPeriodAdjustmentsInventory_bde32da8-d3a3-a756-344a-cb24d9282615" xlink:type="locator" />
    <link:calculationArc order="2" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_clh_BusinessCombinationMeasurementPeriodAdjustmentsNet_d817f90e-ef90-5ff7-8465-cb24d877cd62" xlink:to="loc_clh_BusinessCombinationMeasurementPeriodAdjustmentsInventory_bde32da8-d3a3-a756-344a-cb24d9282615" xlink:type="arc" />
    <link:loc xlink:href="clh-20171231.xsd#clh_BusinessCombinationMeasurementPeriodAdjustmentPrepaidExpensesandOtherAssets" xlink:label="loc_clh_BusinessCombinationMeasurementPeriodAdjustmentPrepaidExpensesandOtherAssets_ef0eabd8-39af-506e-e822-cb24d8de0764" xlink:type="locator" />
    <link:calculationArc order="3" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_clh_BusinessCombinationMeasurementPeriodAdjustmentsNet_d817f90e-ef90-5ff7-8465-cb24d877cd62" xlink:to="loc_clh_BusinessCombinationMeasurementPeriodAdjustmentPrepaidExpensesandOtherAssets_ef0eabd8-39af-506e-e822-cb24d8de0764" xlink:type="arc" />
    <link:loc xlink:href="clh-20171231.xsd#clh_BusinessCombinationMeasurementPeriodAdjustmentsPropertyPlantandEquipment" xlink:label="loc_clh_BusinessCombinationMeasurementPeriodAdjustmentsPropertyPlantandEquipment_246d9a66-8f97-c91a-ca75-cb24d8e746b7" xlink:type="locator" />
    <link:calculationArc order="4" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_clh_BusinessCombinationMeasurementPeriodAdjustmentsNet_d817f90e-ef90-5ff7-8465-cb24d877cd62" xlink:to="loc_clh_BusinessCombinationMeasurementPeriodAdjustmentsPropertyPlantandEquipment_246d9a66-8f97-c91a-ca75-cb24d8e746b7" xlink:type="arc" />
    <link:loc xlink:href="clh-20171231.xsd#clh_BusinessCombinationMeasurementPeriodAdjustmentOtherThanGoodwill" xlink:label="loc_clh_BusinessCombinationMeasurementPeriodAdjustmentOtherThanGoodwill_38e3437a-3c80-7618-e294-cb24d8ec8fab" xlink:type="locator" />
    <link:calculationArc order="5" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_clh_BusinessCombinationMeasurementPeriodAdjustmentsNet_d817f90e-ef90-5ff7-8465-cb24d877cd62" xlink:to="loc_clh_BusinessCombinationMeasurementPeriodAdjustmentOtherThanGoodwill_38e3437a-3c80-7618-e294-cb24d8ec8fab" xlink:type="arc" />
    <link:loc xlink:href="clh-20171231.xsd#clh_BusinessCombinationMeasurementPeriodAdjustmentCurrentLiabilities" xlink:label="loc_clh_BusinessCombinationMeasurementPeriodAdjustmentCurrentLiabilities_6bc2b7f4-c090-4033-eaaf-cb24d9212e55" xlink:type="locator" />
    <link:calculationArc order="6" weight="-1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_clh_BusinessCombinationMeasurementPeriodAdjustmentsNet_d817f90e-ef90-5ff7-8465-cb24d877cd62" xlink:to="loc_clh_BusinessCombinationMeasurementPeriodAdjustmentCurrentLiabilities_6bc2b7f4-c090-4033-eaaf-cb24d9212e55" xlink:type="arc" />
    <link:loc xlink:href="clh-20171231.xsd#clh_BusinessCombinationMeasurementPeriodAdjustmentsClosureandPostClosureLiabilities" xlink:label="loc_clh_BusinessCombinationMeasurementPeriodAdjustmentsClosureandPostClosureLiabilities_43c81c9c-6c5c-c8ac-8f6f-cb24d86dd5ab" xlink:type="locator" />
    <link:calculationArc order="7" weight="-1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_clh_BusinessCombinationMeasurementPeriodAdjustmentsNet_d817f90e-ef90-5ff7-8465-cb24d877cd62" xlink:to="loc_clh_BusinessCombinationMeasurementPeriodAdjustmentsClosureandPostClosureLiabilities_43c81c9c-6c5c-c8ac-8f6f-cb24d86dd5ab" xlink:type="arc" />
    <link:loc xlink:href="clh-20171231.xsd#clh_BusinessCombinationMeasurementPeriodAdjustmentsRemedialLiabilitiesExcludingCurrentPortion" xlink:label="loc_clh_BusinessCombinationMeasurementPeriodAdjustmentsRemedialLiabilitiesExcludingCurrentPortion_75faef9a-bc80-6108-3b35-cb24d8fe1d0a" xlink:type="locator" />
    <link:calculationArc order="8" weight="-1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_clh_BusinessCombinationMeasurementPeriodAdjustmentsNet_d817f90e-ef90-5ff7-8465-cb24d877cd62" xlink:to="loc_clh_BusinessCombinationMeasurementPeriodAdjustmentsRemedialLiabilitiesExcludingCurrentPortion_75faef9a-bc80-6108-3b35-cb24d8fe1d0a" xlink:type="arc" />
    <link:loc xlink:href="clh-20171231.xsd#clh_BusinessCombinationMeasurementPeriodAdjustmentsDeferredTaxesUnrecognizedTaxBenefitsandOtherLongTermLiabilities" xlink:label="loc_clh_BusinessCombinationMeasurementPeriodAdjustmentsDeferredTaxesUnrecognizedTaxBenefitsandOtherLongTermLiabilities_1d98efa3-63f0-a292-359c-cb24d858e859" xlink:type="locator" />
    <link:calculationArc order="9" weight="-1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_clh_BusinessCombinationMeasurementPeriodAdjustmentsNet_d817f90e-ef90-5ff7-8465-cb24d877cd62" xlink:to="loc_clh_BusinessCombinationMeasurementPeriodAdjustmentsDeferredTaxesUnrecognizedTaxBenefitsandOtherLongTermLiabilities_1d98efa3-63f0-a292-359c-cb24d858e859" xlink:type="arc" />
    <link:loc xlink:href="clh-20171231.xsd#clh_BusinessCombinationMeasurementPeriodAdjustmentGoodwill" xlink:label="loc_clh_BusinessCombinationMeasurementPeriodAdjustmentGoodwill_c35c7562-f4f0-3559-7722-cb24d91a3139" xlink:type="locator" />
    <link:calculationArc order="2" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_clh_BusinessCombinationMeasurementPeriodAdjustmentGoodwillAndLiabilitiesAssumedNet_68908ac4-78a9-27f4-728f-cb24d90dff6d" xlink:to="loc_clh_BusinessCombinationMeasurementPeriodAdjustmentGoodwill_c35c7562-f4f0-3559-7722-cb24d91a3139" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredGoodwillAndLiabilitiesAssumedNet" xlink:label="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredGoodwillAndLiabilitiesAssumedNet_017de627-23c1-637c-52df-ee2eb736b728" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_Goodwill" xlink:label="loc_us-gaap_Goodwill_93a64cae-271a-5e6b-8c83-5adf9f941142" xlink:type="locator" />
    <link:calculationArc order="1" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredGoodwillAndLiabilitiesAssumedNet_017de627-23c1-637c-52df-ee2eb736b728" xlink:to="loc_us-gaap_Goodwill_93a64cae-271a-5e6b-8c83-5adf9f941142" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedNet" xlink:label="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedNet_e66eb458-8500-fc68-5c5a-c52959376fd5" xlink:type="locator" />
    <link:calculationArc order="2" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredGoodwillAndLiabilitiesAssumedNet_017de627-23c1-637c-52df-ee2eb736b728" xlink:to="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedNet_e66eb458-8500-fc68-5c5a-c52959376fd5" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedCurrentAssetsReceivables" xlink:label="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedCurrentAssetsReceivables_95ec2852-df8b-d033-5d13-a8d506cf481d" xlink:type="locator" />
    <link:calculationArc order="1" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedNet_e66eb458-8500-fc68-5c5a-c52959376fd5" xlink:to="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedCurrentAssetsReceivables_95ec2852-df8b-d033-5d13-a8d506cf481d" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedInventory" xlink:label="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedInventory_de234906-4555-79c4-6c13-51f5af410421" xlink:type="locator" />
    <link:calculationArc order="2" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedNet_e66eb458-8500-fc68-5c5a-c52959376fd5" xlink:to="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedInventory_de234906-4555-79c4-6c13-51f5af410421" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedCurrentAssetsPrepaidExpenseAndOtherAssets" xlink:label="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedCurrentAssetsPrepaidExpenseAndOtherAssets_31b59b3c-3561-f961-13ba-e3cc74150736" xlink:type="locator" />
    <link:calculationArc order="3" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedNet_e66eb458-8500-fc68-5c5a-c52959376fd5" xlink:to="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedCurrentAssetsPrepaidExpenseAndOtherAssets_31b59b3c-3561-f961-13ba-e3cc74150736" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedPropertyPlantAndEquipment" xlink:label="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedPropertyPlantAndEquipment_4e5d7007-764c-d3cb-5dbd-3a33b1b3941c" xlink:type="locator" />
    <link:calculationArc order="4" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedNet_e66eb458-8500-fc68-5c5a-c52959376fd5" xlink:to="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedPropertyPlantAndEquipment_4e5d7007-764c-d3cb-5dbd-3a33b1b3941c" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedIntangibleAssetsOtherThanGoodwill" xlink:label="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedIntangibleAssetsOtherThanGoodwill_ea5f0c55-82ec-3013-b10d-5cbd46212889" xlink:type="locator" />
    <link:calculationArc order="5" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedNet_e66eb458-8500-fc68-5c5a-c52959376fd5" xlink:to="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedIntangibleAssetsOtherThanGoodwill_ea5f0c55-82ec-3013-b10d-5cbd46212889" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedCurrentLiabilities" xlink:label="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedCurrentLiabilities_be81a681-04d4-2a84-d950-11ec53ecb0e8" xlink:type="locator" />
    <link:calculationArc order="6" weight="-1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedNet_e66eb458-8500-fc68-5c5a-c52959376fd5" xlink:to="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedCurrentLiabilities_be81a681-04d4-2a84-d950-11ec53ecb0e8" xlink:type="arc" />
    <link:loc xlink:href="clh-20171231.xsd#clh_BusinessCombinationRecognizedIdentifiableAssetsAcquiredandLiabilitiesAssumedNoncurrentLiabilitiesClosureandPostClosureLiabilities" xlink:label="loc_clh_BusinessCombinationRecognizedIdentifiableAssetsAcquiredandLiabilitiesAssumedNoncurrentLiabilitiesClosureandPostClosureLiabilities_19fcc560-1f26-c948-3453-cb24d91c2d8e" xlink:type="locator" />
    <link:calculationArc order="7" weight="-1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedNet_e66eb458-8500-fc68-5c5a-c52959376fd5" xlink:to="loc_clh_BusinessCombinationRecognizedIdentifiableAssetsAcquiredandLiabilitiesAssumedNoncurrentLiabilitiesClosureandPostClosureLiabilities_19fcc560-1f26-c948-3453-cb24d91c2d8e" xlink:type="arc" />
    <link:loc xlink:href="clh-20171231.xsd#clh_BusinessCombinationRecognizedIdentifiableAssetsAcquiredandLiabilitiesAssumedRemedialLiabilitiesExcludingCurrentPortion" xlink:label="loc_clh_BusinessCombinationRecognizedIdentifiableAssetsAcquiredandLiabilitiesAssumedRemedialLiabilitiesExcludingCurrentPortion_e702bf7b-e8ab-7cd9-4e8d-cb24d8670658" xlink:type="locator" />
    <link:calculationArc order="8" weight="-1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedNet_e66eb458-8500-fc68-5c5a-c52959376fd5" xlink:to="loc_clh_BusinessCombinationRecognizedIdentifiableAssetsAcquiredandLiabilitiesAssumedRemedialLiabilitiesExcludingCurrentPortion_e702bf7b-e8ab-7cd9-4e8d-cb24d8670658" xlink:type="arc" />
    <link:loc xlink:href="clh-20171231.xsd#clh_BusinessCombinationRecognizedIdentifiableAssetsAcquiredandLiabilitiesAssumedNoncurrentLiabilitiesDeferredTaxesUnrecognizedTaxBenefitsandOtherLongtermLiabilities" xlink:label="loc_clh_BusinessCombinationRecognizedIdentifiableAssetsAcquiredandLiabilitiesAssumedNoncurrentLiabilitiesDeferredTaxesUnrecognizedTaxBenefitsandOtherLongtermLiabilities_8d811d26-5ad1-ec69-09a4-cb24d8d5456f" xlink:type="locator" />
    <link:calculationArc order="9" weight="-1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedNet_e66eb458-8500-fc68-5c5a-c52959376fd5" xlink:to="loc_clh_BusinessCombinationRecognizedIdentifiableAssetsAcquiredandLiabilitiesAssumedNoncurrentLiabilitiesDeferredTaxesUnrecognizedTaxBenefitsandOtherLongtermLiabilities_8d811d26-5ad1-ec69-09a4-cb24d8d5456f" xlink:type="arc" />
  </link:calculationLink>
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/BusinessCombinations2016AcquisitionsNarrativeDetails" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/BusinessCombinations2017AcquisitionsDetails" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/BusinessCombinationsTables" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/ClosureAndPostClosureLiabilities" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/ClosureAndPostClosureLiabilitiesAnticipatedPaymentsDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_AssetRetirementObligation" xlink:label="loc_us-gaap_AssetRetirementObligation_788f260f-96f5-1f63-3187-7ef30405e539" xlink:type="locator" />
    <link:loc xlink:href="clh-20171231.xsd#clh_UndiscountedClosureAndPostClosureLiabilities" xlink:label="loc_clh_UndiscountedClosureAndPostClosureLiabilities_9984d642-dbed-f52f-d38a-32a6cde7705e" xlink:type="locator" />
    <link:calculationArc order="1" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AssetRetirementObligation_788f260f-96f5-1f63-3187-7ef30405e539" xlink:to="loc_clh_UndiscountedClosureAndPostClosureLiabilities_9984d642-dbed-f52f-d38a-32a6cde7705e" xlink:type="arc" />
    <link:loc xlink:href="clh-20171231.xsd#clh_AnticipatedPaymentForAssetRetirementObligationsYearOne" xlink:label="loc_clh_AnticipatedPaymentForAssetRetirementObligationsYearOne_3c7edd07-ad70-ee41-fa0f-32a6cf79f7a4" xlink:type="locator" />
    <link:calculationArc order="1" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_clh_UndiscountedClosureAndPostClosureLiabilities_9984d642-dbed-f52f-d38a-32a6cde7705e" xlink:to="loc_clh_AnticipatedPaymentForAssetRetirementObligationsYearOne_3c7edd07-ad70-ee41-fa0f-32a6cf79f7a4" xlink:type="arc" />
    <link:loc xlink:href="clh-20171231.xsd#clh_AnticipatedPaymentForAssetRetirementObligationsYearTwo" xlink:label="loc_clh_AnticipatedPaymentForAssetRetirementObligationsYearTwo_41884636-b4b0-26f3-1e59-32a6ce650065" xlink:type="locator" />
    <link:calculationArc order="2" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_clh_UndiscountedClosureAndPostClosureLiabilities_9984d642-dbed-f52f-d38a-32a6cde7705e" xlink:to="loc_clh_AnticipatedPaymentForAssetRetirementObligationsYearTwo_41884636-b4b0-26f3-1e59-32a6ce650065" xlink:type="arc" />
    <link:loc xlink:href="clh-20171231.xsd#clh_AnticipatedPaymentForAssetRetirementObligationsYearThree" xlink:label="loc_clh_AnticipatedPaymentForAssetRetirementObligationsYearThree_6a53e9ab-c1d5-e4dc-9dd1-32a6cf104a7c" xlink:type="locator" />
    <link:calculationArc order="3" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_clh_UndiscountedClosureAndPostClosureLiabilities_9984d642-dbed-f52f-d38a-32a6cde7705e" xlink:to="loc_clh_AnticipatedPaymentForAssetRetirementObligationsYearThree_6a53e9ab-c1d5-e4dc-9dd1-32a6cf104a7c" xlink:type="arc" />
    <link:loc xlink:href="clh-20171231.xsd#clh_AnticipatedPaymentForAssetRetirementObligationsYearFour" xlink:label="loc_clh_AnticipatedPaymentForAssetRetirementObligationsYearFour_291afb7a-cfdd-d168-56cb-32a6cdb419ca" xlink:type="locator" />
    <link:calculationArc order="4" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_clh_UndiscountedClosureAndPostClosureLiabilities_9984d642-dbed-f52f-d38a-32a6cde7705e" xlink:to="loc_clh_AnticipatedPaymentForAssetRetirementObligationsYearFour_291afb7a-cfdd-d168-56cb-32a6cdb419ca" xlink:type="arc" />
    <link:loc xlink:href="clh-20171231.xsd#clh_AnticipatedPaymentForAssetRetirementObligationsYearFive" xlink:label="loc_clh_AnticipatedPaymentForAssetRetirementObligationsYearFive_f7e8eb47-071d-5a29-6df6-32a6cdf3d4b3" xlink:type="locator" />
    <link:calculationArc order="5" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_clh_UndiscountedClosureAndPostClosureLiabilities_9984d642-dbed-f52f-d38a-32a6cde7705e" xlink:to="loc_clh_AnticipatedPaymentForAssetRetirementObligationsYearFive_f7e8eb47-071d-5a29-6df6-32a6cdf3d4b3" xlink:type="arc" />
    <link:loc xlink:href="clh-20171231.xsd#clh_AnticipatedPaymentForAssetRetirementObligationsAfterYearFive" xlink:label="loc_clh_AnticipatedPaymentForAssetRetirementObligationsAfterYearFive_7ccc15d7-d021-ebb5-d6f0-32a6ce361e0b" xlink:type="locator" />
    <link:calculationArc order="6" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_clh_UndiscountedClosureAndPostClosureLiabilities_9984d642-dbed-f52f-d38a-32a6cde7705e" xlink:to="loc_clh_AnticipatedPaymentForAssetRetirementObligationsAfterYearFive_7ccc15d7-d021-ebb5-d6f0-32a6ce361e0b" xlink:type="arc" />
    <link:loc xlink:href="clh-20171231.xsd#clh_DiscountReserves" xlink:label="loc_clh_DiscountReserves_bac62c22-0ce9-3075-6203-32a6cf80b21c" xlink:type="locator" />
    <link:calculationArc order="2" weight="-1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AssetRetirementObligation_788f260f-96f5-1f63-3187-7ef30405e539" xlink:to="loc_clh_DiscountReserves_bac62c22-0ce9-3075-6203-32a6cf80b21c" xlink:type="arc" />
    <link:loc xlink:href="clh-20171231.xsd#clh_ReservesToBeProvidedOverRemainingSiteLives" xlink:label="loc_clh_ReservesToBeProvidedOverRemainingSiteLives_db0f28ed-1a7f-8b38-928f-32a6cd14d1f6" xlink:type="locator" />
    <link:calculationArc order="3" weight="-1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AssetRetirementObligation_788f260f-96f5-1f63-3187-7ef30405e539" xlink:to="loc_clh_ReservesToBeProvidedOverRemainingSiteLives_db0f28ed-1a7f-8b38-928f-32a6cd14d1f6" xlink:type="arc" />
  </link:calculationLink>
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/ClosureAndPostClosureLiabilitiesChangesInPostClosureLiabilitiesDetails" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/ClosureAndPostClosureLiabilitiesTables" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/CommitmentsAndContingencies" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/CommitmentsAndContingenciesFederalStateAndProvincialEnforcementActionsDetails" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/CommitmentsAndContingenciesLeasesDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_OperatingLeasesFutureMinimumPaymentsDue" xlink:label="loc_us-gaap_OperatingLeasesFutureMinimumPaymentsDue_e7ae0c4b-54d0-1d15-1541-1fb5329d750c" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_OperatingLeasesFutureMinimumPaymentsDueCurrent" xlink:label="loc_us-gaap_OperatingLeasesFutureMinimumPaymentsDueCurrent_5046b63b-148e-eb12-dd52-2a1e8f1e69c0" xlink:type="locator" />
    <link:calculationArc order="1" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OperatingLeasesFutureMinimumPaymentsDue_e7ae0c4b-54d0-1d15-1541-1fb5329d750c" xlink:to="loc_us-gaap_OperatingLeasesFutureMinimumPaymentsDueCurrent_5046b63b-148e-eb12-dd52-2a1e8f1e69c0" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_OperatingLeasesFutureMinimumPaymentsDueInTwoYears" xlink:label="loc_us-gaap_OperatingLeasesFutureMinimumPaymentsDueInTwoYears_483c5d20-89a2-da39-b56f-2ea722d97042" xlink:type="locator" />
    <link:calculationArc order="2" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OperatingLeasesFutureMinimumPaymentsDue_e7ae0c4b-54d0-1d15-1541-1fb5329d750c" xlink:to="loc_us-gaap_OperatingLeasesFutureMinimumPaymentsDueInTwoYears_483c5d20-89a2-da39-b56f-2ea722d97042" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_OperatingLeasesFutureMinimumPaymentsDueInThreeYears" xlink:label="loc_us-gaap_OperatingLeasesFutureMinimumPaymentsDueInThreeYears_b5a3356e-f555-ddd5-297a-b04afe0bfd5c" xlink:type="locator" />
    <link:calculationArc order="3" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OperatingLeasesFutureMinimumPaymentsDue_e7ae0c4b-54d0-1d15-1541-1fb5329d750c" xlink:to="loc_us-gaap_OperatingLeasesFutureMinimumPaymentsDueInThreeYears_b5a3356e-f555-ddd5-297a-b04afe0bfd5c" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_OperatingLeasesFutureMinimumPaymentsDueInFourYears" xlink:label="loc_us-gaap_OperatingLeasesFutureMinimumPaymentsDueInFourYears_6818de09-a032-5221-5ee6-896e1c2d0634" xlink:type="locator" />
    <link:calculationArc order="4" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OperatingLeasesFutureMinimumPaymentsDue_e7ae0c4b-54d0-1d15-1541-1fb5329d750c" xlink:to="loc_us-gaap_OperatingLeasesFutureMinimumPaymentsDueInFourYears_6818de09-a032-5221-5ee6-896e1c2d0634" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_OperatingLeasesFutureMinimumPaymentsDueInFiveYears" xlink:label="loc_us-gaap_OperatingLeasesFutureMinimumPaymentsDueInFiveYears_56f89e4f-d247-3cf0-a749-00554ab475a6" xlink:type="locator" />
    <link:calculationArc order="5" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OperatingLeasesFutureMinimumPaymentsDue_e7ae0c4b-54d0-1d15-1541-1fb5329d750c" xlink:to="loc_us-gaap_OperatingLeasesFutureMinimumPaymentsDueInFiveYears_56f89e4f-d247-3cf0-a749-00554ab475a6" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_OperatingLeasesFutureMinimumPaymentsDueThereafter" xlink:label="loc_us-gaap_OperatingLeasesFutureMinimumPaymentsDueThereafter_fb0efb32-4bb1-57d0-236e-d8af81dc125f" xlink:type="locator" />
    <link:calculationArc order="6" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OperatingLeasesFutureMinimumPaymentsDue_e7ae0c4b-54d0-1d15-1541-1fb5329d750c" xlink:to="loc_us-gaap_OperatingLeasesFutureMinimumPaymentsDueThereafter_fb0efb32-4bb1-57d0-236e-d8af81dc125f" xlink:type="arc" />
  </link:calculationLink>
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/CommitmentsAndContingenciesLegalAndAdministrativeProceedingsDetails" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/CommitmentsAndContingenciesOtherContingenciesDetails" xlink:type="extended">
    <link:loc xlink:href="clh-20171231.xsd#clh_UndiscountedSelfInsuranceLiabilities" xlink:label="loc_clh_UndiscountedSelfInsuranceLiabilities_9d487f37-5156-ea82-672d-32a6ce0b1d7f" xlink:type="locator" />
    <link:loc xlink:href="clh-20171231.xsd#clh_AnticipatedSelfInsurancePaymentsYearOne" xlink:label="loc_clh_AnticipatedSelfInsurancePaymentsYearOne_ceaeb0cd-dce6-a526-aca1-32a6cec70067" xlink:type="locator" />
    <link:calculationArc order="1" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_clh_UndiscountedSelfInsuranceLiabilities_9d487f37-5156-ea82-672d-32a6ce0b1d7f" xlink:to="loc_clh_AnticipatedSelfInsurancePaymentsYearOne_ceaeb0cd-dce6-a526-aca1-32a6cec70067" xlink:type="arc" />
    <link:loc xlink:href="clh-20171231.xsd#clh_AnticipatedSelfInsurancePaymentsYearTwo" xlink:label="loc_clh_AnticipatedSelfInsurancePaymentsYearTwo_a025d1d2-8949-687a-a576-32a6ce0a26aa" xlink:type="locator" />
    <link:calculationArc order="2" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_clh_UndiscountedSelfInsuranceLiabilities_9d487f37-5156-ea82-672d-32a6ce0b1d7f" xlink:to="loc_clh_AnticipatedSelfInsurancePaymentsYearTwo_a025d1d2-8949-687a-a576-32a6ce0a26aa" xlink:type="arc" />
    <link:loc xlink:href="clh-20171231.xsd#clh_AnticipatedSelfInsurancePaymentsYearThree" xlink:label="loc_clh_AnticipatedSelfInsurancePaymentsYearThree_6324a5a8-c465-8e90-121e-32a6cdfc2644" xlink:type="locator" />
    <link:calculationArc order="3" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_clh_UndiscountedSelfInsuranceLiabilities_9d487f37-5156-ea82-672d-32a6ce0b1d7f" xlink:to="loc_clh_AnticipatedSelfInsurancePaymentsYearThree_6324a5a8-c465-8e90-121e-32a6cdfc2644" xlink:type="arc" />
    <link:loc xlink:href="clh-20171231.xsd#clh_AnticipatedSelfInsurancePaymentsYearFour" xlink:label="loc_clh_AnticipatedSelfInsurancePaymentsYearFour_0db1367e-79d4-1549-3fe9-32a6cee7e63f" xlink:type="locator" />
    <link:calculationArc order="4" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_clh_UndiscountedSelfInsuranceLiabilities_9d487f37-5156-ea82-672d-32a6ce0b1d7f" xlink:to="loc_clh_AnticipatedSelfInsurancePaymentsYearFour_0db1367e-79d4-1549-3fe9-32a6cee7e63f" xlink:type="arc" />
    <link:loc xlink:href="clh-20171231.xsd#clh_AnticipatedSelfInsurancePaymentsYearFive" xlink:label="loc_clh_AnticipatedSelfInsurancePaymentsYearFive_d5435eb0-adc2-e3d4-6cc1-32a6ce3aeba8" xlink:type="locator" />
    <link:calculationArc order="5" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_clh_UndiscountedSelfInsuranceLiabilities_9d487f37-5156-ea82-672d-32a6ce0b1d7f" xlink:to="loc_clh_AnticipatedSelfInsurancePaymentsYearFive_d5435eb0-adc2-e3d4-6cc1-32a6ce3aeba8" xlink:type="arc" />
    <link:loc xlink:href="clh-20171231.xsd#clh_AnticipatedSelfInsurancePaymentsThereafter" xlink:label="loc_clh_AnticipatedSelfInsurancePaymentsThereafter_1367fae5-c58f-bab6-d7c4-32a6ce889932" xlink:type="locator" />
    <link:calculationArc order="6" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_clh_UndiscountedSelfInsuranceLiabilities_9d487f37-5156-ea82-672d-32a6ce0b1d7f" xlink:to="loc_clh_AnticipatedSelfInsurancePaymentsThereafter_1367fae5-c58f-bab6-d7c4-32a6ce889932" xlink:type="arc" />
  </link:calculationLink>
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/CommitmentsAndContingenciesOtherContingenciesDetailsCalc2" xlink:type="extended">
    <link:loc xlink:href="clh-20171231.xsd#clh_UndiscountedSelfInsuranceLiabilities" xlink:label="loc_clh_UndiscountedSelfInsuranceLiabilities_DAEAC5430D2DC805D956BE2CAC6AE50C_9d487f37-5156-ea82-672d-32a6ce0b1d7f" xlink:type="locator" />
    <link:loc xlink:href="clh-20171231.xsd#clh_SelfInsuranceDiscountRate" xlink:label="loc_clh_SelfInsuranceDiscountRate_DAEAC5430D2DC805D956BE2CAC6AE50C_66a252a1-cf66-5cfa-84c5-32a6cf017c5c" xlink:type="locator" />
    <link:calculationArc order="1" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_clh_UndiscountedSelfInsuranceLiabilities_DAEAC5430D2DC805D956BE2CAC6AE50C_9d487f37-5156-ea82-672d-32a6ce0b1d7f" xlink:to="loc_clh_SelfInsuranceDiscountRate_DAEAC5430D2DC805D956BE2CAC6AE50C_66a252a1-cf66-5cfa-84c5-32a6cf017c5c" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_SelfInsuranceReserve" xlink:label="loc_us-gaap_SelfInsuranceReserve_DAEAC5430D2DC805D956BE2CAC6AE50C_5d053fcc-6d1d-d33d-5a0a-81db1369a62f" xlink:type="locator" />
    <link:calculationArc order="2" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_clh_UndiscountedSelfInsuranceLiabilities_DAEAC5430D2DC805D956BE2CAC6AE50C_9d487f37-5156-ea82-672d-32a6ce0b1d7f" xlink:to="loc_us-gaap_SelfInsuranceReserve_DAEAC5430D2DC805D956BE2CAC6AE50C_5d053fcc-6d1d-d33d-5a0a-81db1369a62f" xlink:type="arc" />
  </link:calculationLink>
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/CommitmentsAndContingenciesSuperfundProceedingsDetails" xlink:type="extended">
    <link:loc xlink:href="clh-20171231.xsd#clh_SiteContingencyNumberOfSites" xlink:label="loc_clh_SiteContingencyNumberOfSites_f1979fd1-b1e3-0e4f-2534-cb24d8668528" xlink:type="locator" />
    <link:loc xlink:href="clh-20171231.xsd#clh_SiteContingencyNumberOfSitesOwnedByEntity" xlink:label="loc_clh_SiteContingencyNumberOfSitesOwnedByEntity_e5ee3317-2792-6875-36a1-cb24d8dc79b3" xlink:type="locator" />
    <link:calculationArc order="1" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_clh_SiteContingencyNumberOfSites_f1979fd1-b1e3-0e4f-2534-cb24d8668528" xlink:to="loc_clh_SiteContingencyNumberOfSitesOwnedByEntity_e5ee3317-2792-6875-36a1-cb24d8dc79b3" xlink:type="arc" />
    <link:loc xlink:href="clh-20171231.xsd#clh_SiteContingencyNumberOfSitesOwnedByThirdParty" xlink:label="loc_clh_SiteContingencyNumberOfSitesOwnedByThirdParty_3aa3d91a-25b1-7b94-e0b1-cb24d85c94fd" xlink:type="locator" />
    <link:calculationArc order="2" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_clh_SiteContingencyNumberOfSites_f1979fd1-b1e3-0e4f-2534-cb24d8668528" xlink:to="loc_clh_SiteContingencyNumberOfSitesOwnedByThirdParty_3aa3d91a-25b1-7b94-e0b1-cb24d85c94fd" xlink:type="arc" />
    <link:loc xlink:href="clh-20171231.xsd#clh_SiteContingencyEnvironmentalRemediationExpenseNumberOfSitesOwnedByThirdParty" xlink:label="loc_clh_SiteContingencyEnvironmentalRemediationExpenseNumberOfSitesOwnedByThirdParty_b296ebf4-625d-889e-8702-cb24d8e54600" xlink:type="locator" />
    <link:calculationArc order="1" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_clh_SiteContingencyNumberOfSitesOwnedByThirdParty_3aa3d91a-25b1-7b94-e0b1-cb24d85c94fd" xlink:to="loc_clh_SiteContingencyEnvironmentalRemediationExpenseNumberOfSitesOwnedByThirdParty_b296ebf4-625d-889e-8702-cb24d8e54600" xlink:type="arc" />
    <link:loc xlink:href="clh-20171231.xsd#clh_SiteContingencyNotRequiringEnvironmentalRemediationExpenseNumberOfSitesOwnedByThirdParty" xlink:label="loc_clh_SiteContingencyNotRequiringEnvironmentalRemediationExpenseNumberOfSitesOwnedByThirdParty_02e7cf8d-3d03-5110-14fb-cb24d91fd6a4" xlink:type="locator" />
    <link:calculationArc order="2" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_clh_SiteContingencyNumberOfSitesOwnedByThirdParty_3aa3d91a-25b1-7b94-e0b1-cb24d85c94fd" xlink:to="loc_clh_SiteContingencyNotRequiringEnvironmentalRemediationExpenseNumberOfSitesOwnedByThirdParty_02e7cf8d-3d03-5110-14fb-cb24d91fd6a4" xlink:type="arc" />
    <link:loc xlink:href="clh-20171231.xsd#clh_SiteContingencyEnvironmentalRemediationExpenseSettledNumberOfSitesOwnedByThirdParty" xlink:label="loc_clh_SiteContingencyEnvironmentalRemediationExpenseSettledNumberOfSitesOwnedByThirdParty_36be0f55-c0dd-cfe9-3f2d-cb24d862526a" xlink:type="locator" />
    <link:calculationArc order="3" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_clh_SiteContingencyNumberOfSitesOwnedByThirdParty_3aa3d91a-25b1-7b94-e0b1-cb24d85c94fd" xlink:to="loc_clh_SiteContingencyEnvironmentalRemediationExpenseSettledNumberOfSitesOwnedByThirdParty_36be0f55-c0dd-cfe9-3f2d-cb24d862526a" xlink:type="arc" />
  </link:calculationLink>
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/CommitmentsAndContingenciesTables" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/ConsolidatedBalanceSheets" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_LiabilitiesAndStockholdersEquity" xlink:label="loc_us-gaap_LiabilitiesAndStockholdersEquity_159dcb00-b17e-17db-7098-be4159799459" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest" xlink:label="loc_us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest_00443492-92dd-7fc1-13b6-792f3e163e73" xlink:type="locator" />
    <link:calculationArc order="1" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquity_159dcb00-b17e-17db-7098-be4159799459" xlink:to="loc_us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest_00443492-92dd-7fc1-13b6-792f3e163e73" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_CommonStockValue" xlink:label="loc_us-gaap_CommonStockValue_c3f7606a-e7e9-61d5-b60b-b4b059f68b26" xlink:type="locator" />
    <link:calculationArc order="1" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest_00443492-92dd-7fc1-13b6-792f3e163e73" xlink:to="loc_us-gaap_CommonStockValue_c3f7606a-e7e9-61d5-b60b-b4b059f68b26" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_CommonStockIssuedEmployeeTrustDeferred" xlink:label="loc_us-gaap_CommonStockIssuedEmployeeTrustDeferred_312ac4b6-5dbd-fd1a-62bb-58413133ad80" xlink:type="locator" />
    <link:calculationArc order="2" weight="-1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest_00443492-92dd-7fc1-13b6-792f3e163e73" xlink:to="loc_us-gaap_CommonStockIssuedEmployeeTrustDeferred_312ac4b6-5dbd-fd1a-62bb-58413133ad80" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_AdditionalPaidInCapitalCommonStock" xlink:label="loc_us-gaap_AdditionalPaidInCapitalCommonStock_41895068-9590-2880-73df-521995865843" xlink:type="locator" />
    <link:calculationArc order="3" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest_00443492-92dd-7fc1-13b6-792f3e163e73" xlink:to="loc_us-gaap_AdditionalPaidInCapitalCommonStock_41895068-9590-2880-73df-521995865843" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax" xlink:label="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax_04f0961a-a0bc-88cf-6658-3f950da4a458" xlink:type="locator" />
    <link:calculationArc order="4" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest_00443492-92dd-7fc1-13b6-792f3e163e73" xlink:to="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax_04f0961a-a0bc-88cf-6658-3f950da4a458" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_RetainedEarningsAccumulatedDeficit" xlink:label="loc_us-gaap_RetainedEarningsAccumulatedDeficit_065cb284-7fca-cc9b-5752-2feaf74d0011" xlink:type="locator" />
    <link:calculationArc order="5" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest_00443492-92dd-7fc1-13b6-792f3e163e73" xlink:to="loc_us-gaap_RetainedEarningsAccumulatedDeficit_065cb284-7fca-cc9b-5752-2feaf74d0011" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_LiabilitiesNoncurrent" xlink:label="loc_us-gaap_LiabilitiesNoncurrent_ce6ab6ce-f8d5-dad6-a84c-2c96c7d59f75" xlink:type="locator" />
    <link:calculationArc order="2" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquity_159dcb00-b17e-17db-7098-be4159799459" xlink:to="loc_us-gaap_LiabilitiesNoncurrent_ce6ab6ce-f8d5-dad6-a84c-2c96c7d59f75" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_AccruedCappingClosurePostClosureAndEnvironmentalCostsNoncurrent" xlink:label="loc_us-gaap_AccruedCappingClosurePostClosureAndEnvironmentalCostsNoncurrent_e14367a5-03d1-f12d-19a1-7d968a2ad4e4" xlink:type="locator" />
    <link:calculationArc order="1" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesNoncurrent_ce6ab6ce-f8d5-dad6-a84c-2c96c7d59f75" xlink:to="loc_us-gaap_AccruedCappingClosurePostClosureAndEnvironmentalCostsNoncurrent_e14367a5-03d1-f12d-19a1-7d968a2ad4e4" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_AccruedEnvironmentalLossContingenciesNoncurrent" xlink:label="loc_us-gaap_AccruedEnvironmentalLossContingenciesNoncurrent_06e578e9-829a-6464-82a6-339f8f2261c1" xlink:type="locator" />
    <link:calculationArc order="2" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesNoncurrent_ce6ab6ce-f8d5-dad6-a84c-2c96c7d59f75" xlink:to="loc_us-gaap_AccruedEnvironmentalLossContingenciesNoncurrent_06e578e9-829a-6464-82a6-339f8f2261c1" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_LongTermDebtNoncurrent" xlink:label="loc_us-gaap_LongTermDebtNoncurrent_822b66ff-44a1-e66b-5e0c-09356970a23d" xlink:type="locator" />
    <link:calculationArc order="3" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesNoncurrent_ce6ab6ce-f8d5-dad6-a84c-2c96c7d59f75" xlink:to="loc_us-gaap_LongTermDebtNoncurrent_822b66ff-44a1-e66b-5e0c-09356970a23d" xlink:type="arc" />
    <link:loc xlink:href="clh-20171231.xsd#clh_UnrecognizedTaxBenefitsAndOtherLongTermLiabilitiesNoncurrent" xlink:label="loc_clh_UnrecognizedTaxBenefitsAndOtherLongTermLiabilitiesNoncurrent_12ee4f85-5e55-66d8-2a81-cb24d923daf6" xlink:type="locator" />
    <link:calculationArc order="4" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesNoncurrent_ce6ab6ce-f8d5-dad6-a84c-2c96c7d59f75" xlink:to="loc_clh_UnrecognizedTaxBenefitsAndOtherLongTermLiabilitiesNoncurrent_12ee4f85-5e55-66d8-2a81-cb24d923daf6" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_LiabilitiesCurrent" xlink:label="loc_us-gaap_LiabilitiesCurrent_f5e246cf-e80f-d00b-c8ed-4796aa2df4b4" xlink:type="locator" />
    <link:calculationArc order="3" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquity_159dcb00-b17e-17db-7098-be4159799459" xlink:to="loc_us-gaap_LiabilitiesCurrent_f5e246cf-e80f-d00b-c8ed-4796aa2df4b4" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_AccountsPayableCurrent" xlink:label="loc_us-gaap_AccountsPayableCurrent_7a72b51a-735c-1ad4-bd3f-d9bcf2d6a26d" xlink:type="locator" />
    <link:calculationArc order="1" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesCurrent_f5e246cf-e80f-d00b-c8ed-4796aa2df4b4" xlink:to="loc_us-gaap_AccountsPayableCurrent_7a72b51a-735c-1ad4-bd3f-d9bcf2d6a26d" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DeferredRevenueAndCreditsCurrent" xlink:label="loc_us-gaap_DeferredRevenueAndCreditsCurrent_6731e9e1-bfb2-76de-c1de-51076d3ff7a2" xlink:type="locator" />
    <link:calculationArc order="2" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesCurrent_f5e246cf-e80f-d00b-c8ed-4796aa2df4b4" xlink:to="loc_us-gaap_DeferredRevenueAndCreditsCurrent_6731e9e1-bfb2-76de-c1de-51076d3ff7a2" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_AccruedLiabilitiesCurrent" xlink:label="loc_us-gaap_AccruedLiabilitiesCurrent_3fe8f96b-142b-97b1-3b39-b8d22cd10e98" xlink:type="locator" />
    <link:calculationArc order="3" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesCurrent_f5e246cf-e80f-d00b-c8ed-4796aa2df4b4" xlink:to="loc_us-gaap_AccruedLiabilitiesCurrent_3fe8f96b-142b-97b1-3b39-b8d22cd10e98" xlink:type="arc" />
    <link:loc xlink:href="clh-20171231.xsd#clh_AccruedCappingClosurePostClosureAndRemedialLiabilitiesCurrent" xlink:label="loc_clh_AccruedCappingClosurePostClosureAndRemedialLiabilitiesCurrent_07b89e22-a2aa-451c-432b-cb24d874641b" xlink:type="locator" />
    <link:calculationArc order="4" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesCurrent_f5e246cf-e80f-d00b-c8ed-4796aa2df4b4" xlink:to="loc_clh_AccruedCappingClosurePostClosureAndRemedialLiabilitiesCurrent_07b89e22-a2aa-451c-432b-cb24d874641b" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_LongTermDebtCurrent" xlink:label="loc_us-gaap_LongTermDebtCurrent_f61bf97e-c3a5-ba72-7591-eba8e7bb6a44" xlink:type="locator" />
    <link:calculationArc order="5" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesCurrent_f5e246cf-e80f-d00b-c8ed-4796aa2df4b4" xlink:to="loc_us-gaap_LongTermDebtCurrent_f61bf97e-c3a5-ba72-7591-eba8e7bb6a44" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_CommitmentsAndContingencies" xlink:label="loc_us-gaap_CommitmentsAndContingencies_058e01e4-b9a1-623e-29f5-1b5c79bf095a" xlink:type="locator" />
    <link:calculationArc order="4" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquity_159dcb00-b17e-17db-7098-be4159799459" xlink:to="loc_us-gaap_CommitmentsAndContingencies_058e01e4-b9a1-623e-29f5-1b5c79bf095a" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_Assets" xlink:label="loc_us-gaap_Assets_c6057b1d-6685-8249-2051-6c57f3a16a9e" xlink:type="locator" />
    <link:loc xlink:href="clh-20171231.xsd#clh_AssetsNoncurrentExcludingPropertyPlantAndEquipment" xlink:label="loc_clh_AssetsNoncurrentExcludingPropertyPlantAndEquipment_0a363694-3bd5-e286-afa6-cb24d871fa27" xlink:type="locator" />
    <link:calculationArc order="1" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Assets_c6057b1d-6685-8249-2051-6c57f3a16a9e" xlink:to="loc_clh_AssetsNoncurrentExcludingPropertyPlantAndEquipment_0a363694-3bd5-e286-afa6-cb24d871fa27" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_Goodwill" xlink:label="loc_us-gaap_Goodwill_93a64cae-271a-5e6b-8c83-5adf9f941142" xlink:type="locator" />
    <link:calculationArc order="1" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_clh_AssetsNoncurrentExcludingPropertyPlantAndEquipment_0a363694-3bd5-e286-afa6-cb24d871fa27" xlink:to="loc_us-gaap_Goodwill_93a64cae-271a-5e6b-8c83-5adf9f941142" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_IntangibleAssetsNetExcludingGoodwill" xlink:label="loc_us-gaap_IntangibleAssetsNetExcludingGoodwill_1fe06082-076b-052d-6e2e-930afe9d6b2d" xlink:type="locator" />
    <link:calculationArc order="2" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_clh_AssetsNoncurrentExcludingPropertyPlantAndEquipment_0a363694-3bd5-e286-afa6-cb24d871fa27" xlink:to="loc_us-gaap_IntangibleAssetsNetExcludingGoodwill_1fe06082-076b-052d-6e2e-930afe9d6b2d" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_OtherAssetsNoncurrent" xlink:label="loc_us-gaap_OtherAssetsNoncurrent_9b27fab9-d497-627b-4cfb-6b585220b978" xlink:type="locator" />
    <link:calculationArc order="3" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_clh_AssetsNoncurrentExcludingPropertyPlantAndEquipment_0a363694-3bd5-e286-afa6-cb24d871fa27" xlink:to="loc_us-gaap_OtherAssetsNoncurrent_9b27fab9-d497-627b-4cfb-6b585220b978" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_AssetsCurrent" xlink:label="loc_us-gaap_AssetsCurrent_8a47066b-3628-88d1-49db-ed09aecc7fc7" xlink:type="locator" />
    <link:calculationArc order="2" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Assets_c6057b1d-6685-8249-2051-6c57f3a16a9e" xlink:to="loc_us-gaap_AssetsCurrent_8a47066b-3628-88d1-49db-ed09aecc7fc7" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_CashAndCashEquivalentsAtCarryingValue" xlink:label="loc_us-gaap_CashAndCashEquivalentsAtCarryingValue_07da1db4-2708-4446-4250-1fdd5956185e" xlink:type="locator" />
    <link:calculationArc order="1" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AssetsCurrent_8a47066b-3628-88d1-49db-ed09aecc7fc7" xlink:to="loc_us-gaap_CashAndCashEquivalentsAtCarryingValue_07da1db4-2708-4446-4250-1fdd5956185e" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_AccountsReceivableNetCurrent" xlink:label="loc_us-gaap_AccountsReceivableNetCurrent_dd7775cd-f4ab-5607-9b31-1ee98f605818" xlink:type="locator" />
    <link:calculationArc order="2" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AssetsCurrent_8a47066b-3628-88d1-49db-ed09aecc7fc7" xlink:to="loc_us-gaap_AccountsReceivableNetCurrent_dd7775cd-f4ab-5607-9b31-1ee98f605818" xlink:type="arc" />
    <link:loc xlink:href="clh-20171231.xsd#clh_UnbilledAccountsReceivableCurrent" xlink:label="loc_clh_UnbilledAccountsReceivableCurrent_0c5baee0-f44e-ab85-b4f8-cb24d91d034f" xlink:type="locator" />
    <link:calculationArc order="3" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AssetsCurrent_8a47066b-3628-88d1-49db-ed09aecc7fc7" xlink:to="loc_clh_UnbilledAccountsReceivableCurrent_0c5baee0-f44e-ab85-b4f8-cb24d91d034f" xlink:type="arc" />
    <link:loc xlink:href="clh-20171231.xsd#clh_PrepaidExpensesAndOtherAssetsCurrent" xlink:label="loc_clh_PrepaidExpensesAndOtherAssetsCurrent_c99f1ebd-2d61-9e53-50c3-32a6ce106599" xlink:type="locator" />
    <link:calculationArc order="4" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AssetsCurrent_8a47066b-3628-88d1-49db-ed09aecc7fc7" xlink:to="loc_clh_PrepaidExpensesAndOtherAssetsCurrent_c99f1ebd-2d61-9e53-50c3-32a6ce106599" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_Supplies" xlink:label="loc_us-gaap_Supplies_d6f4772c-e6e5-f7ea-9ac8-7139c6506826" xlink:type="locator" />
    <link:calculationArc order="5" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AssetsCurrent_8a47066b-3628-88d1-49db-ed09aecc7fc7" xlink:to="loc_us-gaap_Supplies_d6f4772c-e6e5-f7ea-9ac8-7139c6506826" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DeferredFinanceCostsCurrentNet" xlink:label="loc_us-gaap_DeferredFinanceCostsCurrentNet_5a454d86-13e3-0a5f-9f0c-ce61a35dc172" xlink:type="locator" />
    <link:calculationArc order="6" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AssetsCurrent_8a47066b-3628-88d1-49db-ed09aecc7fc7" xlink:to="loc_us-gaap_DeferredFinanceCostsCurrentNet_5a454d86-13e3-0a5f-9f0c-ce61a35dc172" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_MarketableSecuritiesCurrent" xlink:label="loc_us-gaap_MarketableSecuritiesCurrent_77be6853-2f03-c976-4472-a91565f93300" xlink:type="locator" />
    <link:calculationArc order="7" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AssetsCurrent_8a47066b-3628-88d1-49db-ed09aecc7fc7" xlink:to="loc_us-gaap_MarketableSecuritiesCurrent_77be6853-2f03-c976-4472-a91565f93300" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_PropertyPlantAndEquipmentNet" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentNet_1944a381-5c4e-ce3c-9111-13ccd1c639db" xlink:type="locator" />
    <link:calculationArc order="3" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Assets_c6057b1d-6685-8249-2051-6c57f3a16a9e" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentNet_1944a381-5c4e-ce3c-9111-13ccd1c639db" xlink:type="arc" />
  </link:calculationLink>
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/ConsolidatedBalanceSheetsParenthetical" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/ConsolidatedStatementsOfCashFlows" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_CashAndCashEquivalentsPeriodIncreaseDecrease" xlink:label="loc_us-gaap_CashAndCashEquivalentsPeriodIncreaseDecrease_dd2e9db6-10f9-d78a-ba84-b18268245a83" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_EffectOfExchangeRateOnCashAndCashEquivalents" xlink:label="loc_us-gaap_EffectOfExchangeRateOnCashAndCashEquivalents_8629a772-7004-5d77-9980-0f501e29c5c8" xlink:type="locator" />
    <link:calculationArc order="1" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_CashAndCashEquivalentsPeriodIncreaseDecrease_dd2e9db6-10f9-d78a-ba84-b18268245a83" xlink:to="loc_us-gaap_EffectOfExchangeRateOnCashAndCashEquivalents_8629a772-7004-5d77-9980-0f501e29c5c8" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_NetCashProvidedByUsedInFinancingActivities" xlink:label="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_deb49b68-c030-7624-a39d-ea301caa5dbf" xlink:type="locator" />
    <link:calculationArc order="2" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_CashAndCashEquivalentsPeriodIncreaseDecrease_dd2e9db6-10f9-d78a-ba84-b18268245a83" xlink:to="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_deb49b68-c030-7624-a39d-ea301caa5dbf" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_NetCashProvidedByUsedInInvestingActivities" xlink:label="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_70319186-e7bd-7189-88d2-eba26fb93350" xlink:type="locator" />
    <link:calculationArc order="3" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_CashAndCashEquivalentsPeriodIncreaseDecrease_dd2e9db6-10f9-d78a-ba84-b18268245a83" xlink:to="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_70319186-e7bd-7189-88d2-eba26fb93350" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_NetCashProvidedByUsedInOperatingActivities" xlink:label="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_444b1ac7-f47a-4ce3-0caa-537f7e4ab8c3" xlink:type="locator" />
    <link:calculationArc order="4" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_CashAndCashEquivalentsPeriodIncreaseDecrease_dd2e9db6-10f9-d78a-ba84-b18268245a83" xlink:to="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_444b1ac7-f47a-4ce3-0caa-537f7e4ab8c3" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ProfitLoss" xlink:label="loc_us-gaap_ProfitLoss_adacf05e-7e15-bd60-3e53-87432885dc29" xlink:type="locator" />
    <link:calculationArc order="1" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_444b1ac7-f47a-4ce3-0caa-537f7e4ab8c3" xlink:to="loc_us-gaap_ProfitLoss_adacf05e-7e15-bd60-3e53-87432885dc29" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DepreciationDepletionAndAmortization" xlink:label="loc_us-gaap_DepreciationDepletionAndAmortization_37b0c31d-5d8b-0577-dfd9-aa56a79334e3" xlink:type="locator" />
    <link:calculationArc order="2" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_444b1ac7-f47a-4ce3-0caa-537f7e4ab8c3" xlink:to="loc_us-gaap_DepreciationDepletionAndAmortization_37b0c31d-5d8b-0577-dfd9-aa56a79334e3" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_GoodwillImpairmentLoss" xlink:label="loc_us-gaap_GoodwillImpairmentLoss_fca284fd-6d29-9ad5-2fe0-048c9053b712" xlink:type="locator" />
    <link:calculationArc order="3" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_444b1ac7-f47a-4ce3-0caa-537f7e4ab8c3" xlink:to="loc_us-gaap_GoodwillImpairmentLoss_fca284fd-6d29-9ad5-2fe0-048c9053b712" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ProvisionForDoubtfulAccounts" xlink:label="loc_us-gaap_ProvisionForDoubtfulAccounts_3bb02469-191c-4baa-c8ee-e08be21b11bb" xlink:type="locator" />
    <link:calculationArc order="4" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_444b1ac7-f47a-4ce3-0caa-537f7e4ab8c3" xlink:to="loc_us-gaap_ProvisionForDoubtfulAccounts_3bb02469-191c-4baa-c8ee-e08be21b11bb" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_AmortizationOfFinancingCostsAndDiscounts" xlink:label="loc_us-gaap_AmortizationOfFinancingCostsAndDiscounts_e9a2cdf1-6f49-806b-7b55-b9320bcfa87f" xlink:type="locator" />
    <link:calculationArc order="5" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_444b1ac7-f47a-4ce3-0caa-537f7e4ab8c3" xlink:to="loc_us-gaap_AmortizationOfFinancingCostsAndDiscounts_e9a2cdf1-6f49-806b-7b55-b9320bcfa87f" xlink:type="arc" />
    <link:loc xlink:href="clh-20171231.xsd#clh_AccretionOfEnvironmentalLiabilities" xlink:label="loc_clh_AccretionOfEnvironmentalLiabilities_b2493bcd-b4b5-8fe0-cc7a-cb24d8f78231" xlink:type="locator" />
    <link:calculationArc order="6" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_444b1ac7-f47a-4ce3-0caa-537f7e4ab8c3" xlink:to="loc_clh_AccretionOfEnvironmentalLiabilities_b2493bcd-b4b5-8fe0-cc7a-cb24d8f78231" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_OtherIncreaseDecreaseInEnvironmentalLiabilities" xlink:label="loc_us-gaap_OtherIncreaseDecreaseInEnvironmentalLiabilities_6152f341-d0bc-7269-8880-cab17630e00f" xlink:type="locator" />
    <link:calculationArc order="7" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_444b1ac7-f47a-4ce3-0caa-537f7e4ab8c3" xlink:to="loc_us-gaap_OtherIncreaseDecreaseInEnvironmentalLiabilities_6152f341-d0bc-7269-8880-cab17630e00f" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DeferredIncomeTaxExpenseBenefit" xlink:label="loc_us-gaap_DeferredIncomeTaxExpenseBenefit_f75d01b7-d271-b07d-c4a7-6ae60293303d" xlink:type="locator" />
    <link:calculationArc order="8" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_444b1ac7-f47a-4ce3-0caa-537f7e4ab8c3" xlink:to="loc_us-gaap_DeferredIncomeTaxExpenseBenefit_f75d01b7-d271-b07d-c4a7-6ae60293303d" xlink:type="arc" />
    <link:loc xlink:href="clh-20171231.xsd#clh_GainLossOnSaleOfFixedAssetsAndAssetsHeldForSale" xlink:label="loc_clh_GainLossOnSaleOfFixedAssetsAndAssetsHeldForSale_c3d3ce6b-b06c-de44-85b2-32a6cd105833" xlink:type="locator" />
    <link:calculationArc order="9" weight="-1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_444b1ac7-f47a-4ce3-0caa-537f7e4ab8c3" xlink:to="loc_clh_GainLossOnSaleOfFixedAssetsAndAssetsHeldForSale_c3d3ce6b-b06c-de44-85b2-32a6cd105833" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ShareBasedCompensation" xlink:label="loc_us-gaap_ShareBasedCompensation_e3eecf87-b290-4567-8a59-5b0a8e27c85b" xlink:type="locator" />
    <link:calculationArc order="10" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_444b1ac7-f47a-4ce3-0caa-537f7e4ab8c3" xlink:to="loc_us-gaap_ShareBasedCompensation_e3eecf87-b290-4567-8a59-5b0a8e27c85b" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ExcessTaxBenefitFromShareBasedCompensationOperatingActivities" xlink:label="loc_us-gaap_ExcessTaxBenefitFromShareBasedCompensationOperatingActivities_94d761b7-b8f1-3ba3-90b8-1443c3232b73" xlink:type="locator" />
    <link:calculationArc order="11" weight="-1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_444b1ac7-f47a-4ce3-0caa-537f7e4ab8c3" xlink:to="loc_us-gaap_ExcessTaxBenefitFromShareBasedCompensationOperatingActivities_94d761b7-b8f1-3ba3-90b8-1443c3232b73" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_GainLossOnSaleOfBusiness" xlink:label="loc_us-gaap_GainLossOnSaleOfBusiness_0427ef0c-6a82-1061-c648-71b3a1a70634" xlink:type="locator" />
    <link:calculationArc order="12" weight="-1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_444b1ac7-f47a-4ce3-0caa-537f7e4ab8c3" xlink:to="loc_us-gaap_GainLossOnSaleOfBusiness_0427ef0c-6a82-1061-c648-71b3a1a70634" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_PaymentsForEnvironmentalLiabilities" xlink:label="loc_us-gaap_PaymentsForEnvironmentalLiabilities_f378bf9b-c094-5ae2-1590-7a7f9038b1aa" xlink:type="locator" />
    <link:calculationArc order="13" weight="-1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_444b1ac7-f47a-4ce3-0caa-537f7e4ab8c3" xlink:to="loc_us-gaap_PaymentsForEnvironmentalLiabilities_f378bf9b-c094-5ae2-1590-7a7f9038b1aa" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_IncreaseDecreaseInAccountsReceivable" xlink:label="loc_us-gaap_IncreaseDecreaseInAccountsReceivable_dd4bfa5e-1979-c817-e8a9-371104c0d4f7" xlink:type="locator" />
    <link:calculationArc order="14" weight="-1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_444b1ac7-f47a-4ce3-0caa-537f7e4ab8c3" xlink:to="loc_us-gaap_IncreaseDecreaseInAccountsReceivable_dd4bfa5e-1979-c817-e8a9-371104c0d4f7" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_IncreaseDecreaseInInventories" xlink:label="loc_us-gaap_IncreaseDecreaseInInventories_bf3f9720-ba63-7ecd-52ae-e754a6f349db" xlink:type="locator" />
    <link:calculationArc order="15" weight="-1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_444b1ac7-f47a-4ce3-0caa-537f7e4ab8c3" xlink:to="loc_us-gaap_IncreaseDecreaseInInventories_bf3f9720-ba63-7ecd-52ae-e754a6f349db" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_IncreaseDecreaseInOtherOperatingAssets" xlink:label="loc_us-gaap_IncreaseDecreaseInOtherOperatingAssets_ac9066b4-6e40-13ed-8628-1a20304926d8" xlink:type="locator" />
    <link:calculationArc order="16" weight="-1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_444b1ac7-f47a-4ce3-0caa-537f7e4ab8c3" xlink:to="loc_us-gaap_IncreaseDecreaseInOtherOperatingAssets_ac9066b4-6e40-13ed-8628-1a20304926d8" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_IncreaseDecreaseInAccountsPayable" xlink:label="loc_us-gaap_IncreaseDecreaseInAccountsPayable_a8b6fe35-4809-bddf-7ef6-3144a6c89165" xlink:type="locator" />
    <link:calculationArc order="17" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_444b1ac7-f47a-4ce3-0caa-537f7e4ab8c3" xlink:to="loc_us-gaap_IncreaseDecreaseInAccountsPayable_a8b6fe35-4809-bddf-7ef6-3144a6c89165" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_IncreaseDecreaseInOtherOperatingLiabilities" xlink:label="loc_us-gaap_IncreaseDecreaseInOtherOperatingLiabilities_7e3bb724-19f9-7fc7-d3fb-60f34a11e15a" xlink:type="locator" />
    <link:calculationArc order="18" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_444b1ac7-f47a-4ce3-0caa-537f7e4ab8c3" xlink:to="loc_us-gaap_IncreaseDecreaseInOtherOperatingLiabilities_7e3bb724-19f9-7fc7-d3fb-60f34a11e15a" xlink:type="arc" />
    <link:loc xlink:href="clh-20171231.xsd#clh_EmployeeServiceSharebasedCompensationTaxBenefitFromCompensationExpenseNet" xlink:label="loc_clh_EmployeeServiceSharebasedCompensationTaxBenefitFromCompensationExpenseNet_3b1394ef-8b33-8daa-98bc-32a6ce84facd" xlink:type="locator" />
    <link:calculationArc order="19" weight="-1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_444b1ac7-f47a-4ce3-0caa-537f7e4ab8c3" xlink:to="loc_clh_EmployeeServiceSharebasedCompensationTaxBenefitFromCompensationExpenseNet_3b1394ef-8b33-8daa-98bc-32a6ce84facd" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_GainsLossesOnExtinguishmentOfDebt" xlink:label="loc_us-gaap_GainsLossesOnExtinguishmentOfDebt_3db65903-3171-d63c-a688-532ba00b8108" xlink:type="locator" />
    <link:calculationArc order="20" weight="-1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_444b1ac7-f47a-4ce3-0caa-537f7e4ab8c3" xlink:to="loc_us-gaap_GainsLossesOnExtinguishmentOfDebt_3db65903-3171-d63c-a688-532ba00b8108" xlink:type="arc" />
  </link:calculationLink>
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/ConsolidatedStatementsOfComprehensiveIncomeLoss" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ComprehensiveIncomeNetOfTax" xlink:label="loc_us-gaap_ComprehensiveIncomeNetOfTax_499015ce-2160-aed2-85a3-080e8c4c6cdf" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ProfitLoss" xlink:label="loc_us-gaap_ProfitLoss_adacf05e-7e15-bd60-3e53-87432885dc29" xlink:type="locator" />
    <link:calculationArc order="1" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_ComprehensiveIncomeNetOfTax_499015ce-2160-aed2-85a3-080e8c4c6cdf" xlink:to="loc_us-gaap_ProfitLoss_adacf05e-7e15-bd60-3e53-87432885dc29" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent_72d12753-e25c-cdc0-88b6-98db8d7b7fae" xlink:type="locator" />
    <link:calculationArc order="2" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_ComprehensiveIncomeNetOfTax_499015ce-2160-aed2-85a3-080e8c4c6cdf" xlink:to="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent_72d12753-e25c-cdc0-88b6-98db8d7b7fae" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodNetOfTax" xlink:label="loc_us-gaap_OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodNetOfTax_57e8ae74-d8b6-c629-9bee-2d0929cd3999" xlink:type="locator" />
    <link:calculationArc order="1" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent_72d12753-e25c-cdc0-88b6-98db8d7b7fae" xlink:to="loc_us-gaap_OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodNetOfTax_57e8ae74-d8b6-c629-9bee-2d0929cd3999" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossReclassificationAdjustmentFromAOCIForSaleOfSecuritiesNetOfTax" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossReclassificationAdjustmentFromAOCIForSaleOfSecuritiesNetOfTax_ab3008c3-c5c2-a86b-0613-39cbd9b94527" xlink:type="locator" />
    <link:calculationArc order="2" weight="-1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent_72d12753-e25c-cdc0-88b6-98db8d7b7fae" xlink:to="loc_us-gaap_OtherComprehensiveIncomeLossReclassificationAdjustmentFromAOCIForSaleOfSecuritiesNetOfTax_ab3008c3-c5c2-a86b-0613-39cbd9b94527" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationAdjustmentNetOfTaxPortionAttributableToParent" xlink:label="loc_us-gaap_OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationAdjustmentNetOfTaxPortionAttributableToParent_4230dd8a-1a56-db80-c035-2fabf7b960fd" xlink:type="locator" />
    <link:calculationArc order="3" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent_72d12753-e25c-cdc0-88b6-98db8d7b7fae" xlink:to="loc_us-gaap_OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationAdjustmentNetOfTaxPortionAttributableToParent_4230dd8a-1a56-db80-c035-2fabf7b960fd" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_OtherComprehensiveIncomeDefinedBenefitPlansAdjustmentNetOfTaxPortionAttributableToParent" xlink:label="loc_us-gaap_OtherComprehensiveIncomeDefinedBenefitPlansAdjustmentNetOfTaxPortionAttributableToParent_1162958e-3b54-7f44-ae96-63b659f5cdba" xlink:type="locator" />
    <link:calculationArc order="4" weight="-1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent_72d12753-e25c-cdc0-88b6-98db8d7b7fae" xlink:to="loc_us-gaap_OtherComprehensiveIncomeDefinedBenefitPlansAdjustmentNetOfTaxPortionAttributableToParent_1162958e-3b54-7f44-ae96-63b659f5cdba" xlink:type="arc" />
  </link:calculationLink>
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/ConsolidatedStatementsOfComprehensiveIncomeLossParenthetical" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/ConsolidatedStatementsOfOperations" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_OperatingIncomeLoss" xlink:label="loc_us-gaap_OperatingIncomeLoss_9894e895-7695-402a-9f03-08d60b7373b8" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_SellingGeneralAndAdministrativeExpense" xlink:label="loc_us-gaap_SellingGeneralAndAdministrativeExpense_29ad42f4-24c5-90ea-4492-fdb757d66249" xlink:type="locator" />
    <link:calculationArc order="1" weight="-1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OperatingIncomeLoss_9894e895-7695-402a-9f03-08d60b7373b8" xlink:to="loc_us-gaap_SellingGeneralAndAdministrativeExpense_29ad42f4-24c5-90ea-4492-fdb757d66249" xlink:type="arc" />
    <link:loc xlink:href="clh-20171231.xsd#clh_AccretionOfEnvironmentalLiabilities" xlink:label="loc_clh_AccretionOfEnvironmentalLiabilities_b2493bcd-b4b5-8fe0-cc7a-cb24d8f78231" xlink:type="locator" />
    <link:calculationArc order="2" weight="-1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OperatingIncomeLoss_9894e895-7695-402a-9f03-08d60b7373b8" xlink:to="loc_clh_AccretionOfEnvironmentalLiabilities_b2493bcd-b4b5-8fe0-cc7a-cb24d8f78231" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DepreciationDepletionAndAmortization" xlink:label="loc_us-gaap_DepreciationDepletionAndAmortization_37b0c31d-5d8b-0577-dfd9-aa56a79334e3" xlink:type="locator" />
    <link:calculationArc order="3" weight="-1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OperatingIncomeLoss_9894e895-7695-402a-9f03-08d60b7373b8" xlink:to="loc_us-gaap_DepreciationDepletionAndAmortization_37b0c31d-5d8b-0577-dfd9-aa56a79334e3" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_Revenues" xlink:label="loc_us-gaap_Revenues_33f76b65-31cf-be04-0849-25af345446d5" xlink:type="locator" />
    <link:calculationArc order="4" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OperatingIncomeLoss_9894e895-7695-402a-9f03-08d60b7373b8" xlink:to="loc_us-gaap_Revenues_33f76b65-31cf-be04-0849-25af345446d5" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_SalesRevenueServicesNet" xlink:label="loc_us-gaap_SalesRevenueServicesNet_ad6c862c-c374-70de-502e-5f168b553492" xlink:type="locator" />
    <link:calculationArc order="1" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Revenues_33f76b65-31cf-be04-0849-25af345446d5" xlink:to="loc_us-gaap_SalesRevenueServicesNet_ad6c862c-c374-70de-502e-5f168b553492" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_SalesRevenueGoodsNet" xlink:label="loc_us-gaap_SalesRevenueGoodsNet_318cebec-2b05-42bf-a988-02b2e99cecfb" xlink:type="locator" />
    <link:calculationArc order="2" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Revenues_33f76b65-31cf-be04-0849-25af345446d5" xlink:to="loc_us-gaap_SalesRevenueGoodsNet_318cebec-2b05-42bf-a988-02b2e99cecfb" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_CostOfRevenue" xlink:label="loc_us-gaap_CostOfRevenue_a2b142e3-b3f3-b7b6-6428-5812971ab980" xlink:type="locator" />
    <link:calculationArc order="5" weight="-1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OperatingIncomeLoss_9894e895-7695-402a-9f03-08d60b7373b8" xlink:to="loc_us-gaap_CostOfRevenue_a2b142e3-b3f3-b7b6-6428-5812971ab980" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_CostOfServices" xlink:label="loc_us-gaap_CostOfServices_578bfc43-608e-bdc8-e57a-2803c355c0d9" xlink:type="locator" />
    <link:calculationArc order="1" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_CostOfRevenue_a2b142e3-b3f3-b7b6-6428-5812971ab980" xlink:to="loc_us-gaap_CostOfServices_578bfc43-608e-bdc8-e57a-2803c355c0d9" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_CostOfGoodsSold" xlink:label="loc_us-gaap_CostOfGoodsSold_23c68b7c-81fb-cba2-1814-b7ab4991d5d0" xlink:type="locator" />
    <link:calculationArc order="2" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_CostOfRevenue_a2b142e3-b3f3-b7b6-6428-5812971ab980" xlink:to="loc_us-gaap_CostOfGoodsSold_23c68b7c-81fb-cba2-1814-b7ab4991d5d0" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_GoodwillImpairmentLoss" xlink:label="loc_us-gaap_GoodwillImpairmentLoss_fca284fd-6d29-9ad5-2fe0-048c9053b712" xlink:type="locator" />
    <link:calculationArc order="6" weight="-1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OperatingIncomeLoss_9894e895-7695-402a-9f03-08d60b7373b8" xlink:to="loc_us-gaap_GoodwillImpairmentLoss_fca284fd-6d29-9ad5-2fe0-048c9053b712" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ProfitLoss" xlink:label="loc_us-gaap_ProfitLoss_adacf05e-7e15-bd60-3e53-87432885dc29" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments" xlink:label="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments_0eb47183-f513-314d-ceda-ee2412d9eee8" xlink:type="locator" />
    <link:calculationArc order="1" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_ProfitLoss_adacf05e-7e15-bd60-3e53-87432885dc29" xlink:to="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments_0eb47183-f513-314d-ceda-ee2412d9eee8" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_IncomeTaxExpenseBenefit" xlink:label="loc_us-gaap_IncomeTaxExpenseBenefit_78b7d85e-8366-fe6d-cb1f-faac5a041b79" xlink:type="locator" />
    <link:calculationArc order="2" weight="-1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_ProfitLoss_adacf05e-7e15-bd60-3e53-87432885dc29" xlink:to="loc_us-gaap_IncomeTaxExpenseBenefit_78b7d85e-8366-fe6d-cb1f-faac5a041b79" xlink:type="arc" />
  </link:calculationLink>
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/ConsolidatedStatementsOfOperationsParenthetical" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/ConsolidatedStatementsOfStockholdersEquity" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/ConsolidatedStatementsOfStockholdersEquityParenthetical" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/DispositionOfBusiness" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/DispositionOfBusiness2016DispositionDetails" xlink:type="extended">
    <link:loc xlink:href="clh-20171231.xsd#clh_DisposalGroupIncludingDiscontinuedOperationAssetsLiabilitiesNet" xlink:label="loc_clh_DisposalGroupIncludingDiscontinuedOperationAssetsLiabilitiesNet_5E7093E0869789BF5CED3C83E9EBC715" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_AssetsOfDisposalGroupIncludingDiscontinuedOperation" xlink:label="loc_us-gaap_AssetsOfDisposalGroupIncludingDiscontinuedOperation_fbfc68a4-7e65-a720-f5aa-5f1609a206d5" xlink:type="locator" />
    <link:calculationArc order="1" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_clh_DisposalGroupIncludingDiscontinuedOperationAssetsLiabilitiesNet_5E7093E0869789BF5CED3C83E9EBC715" xlink:to="loc_us-gaap_AssetsOfDisposalGroupIncludingDiscontinuedOperation_fbfc68a4-7e65-a720-f5aa-5f1609a206d5" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_AssetsOfDisposalGroupIncludingDiscontinuedOperationCurrent" xlink:label="loc_us-gaap_AssetsOfDisposalGroupIncludingDiscontinuedOperationCurrent_7ccd4058-c821-b334-f2ba-45d4b5754cc1" xlink:type="locator" />
    <link:calculationArc order="1" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AssetsOfDisposalGroupIncludingDiscontinuedOperation_fbfc68a4-7e65-a720-f5aa-5f1609a206d5" xlink:to="loc_us-gaap_AssetsOfDisposalGroupIncludingDiscontinuedOperationCurrent_7ccd4058-c821-b334-f2ba-45d4b5754cc1" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DisposalGroupIncludingDiscontinuedOperationPropertyPlantAndEquipmentNoncurrent" xlink:label="loc_us-gaap_DisposalGroupIncludingDiscontinuedOperationPropertyPlantAndEquipmentNoncurrent_369b720c-3781-7ff4-ba23-58b071bef9b7" xlink:type="locator" />
    <link:calculationArc order="2" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AssetsOfDisposalGroupIncludingDiscontinuedOperation_fbfc68a4-7e65-a720-f5aa-5f1609a206d5" xlink:to="loc_us-gaap_DisposalGroupIncludingDiscontinuedOperationPropertyPlantAndEquipmentNoncurrent_369b720c-3781-7ff4-ba23-58b071bef9b7" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DisposalGroupIncludingDiscontinuedOperationOtherNoncurrentAssets" xlink:label="loc_us-gaap_DisposalGroupIncludingDiscontinuedOperationOtherNoncurrentAssets_c4ddb8fa-14d3-bd62-071d-844519013aa9" xlink:type="locator" />
    <link:calculationArc order="3" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AssetsOfDisposalGroupIncludingDiscontinuedOperation_fbfc68a4-7e65-a720-f5aa-5f1609a206d5" xlink:to="loc_us-gaap_DisposalGroupIncludingDiscontinuedOperationOtherNoncurrentAssets_c4ddb8fa-14d3-bd62-071d-844519013aa9" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_LiabilitiesOfDisposalGroupIncludingDiscontinuedOperation" xlink:label="loc_us-gaap_LiabilitiesOfDisposalGroupIncludingDiscontinuedOperation_364b8af4-cad8-03c2-4998-315e9240f281" xlink:type="locator" />
    <link:calculationArc order="2" weight="-1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_clh_DisposalGroupIncludingDiscontinuedOperationAssetsLiabilitiesNet_5E7093E0869789BF5CED3C83E9EBC715" xlink:to="loc_us-gaap_LiabilitiesOfDisposalGroupIncludingDiscontinuedOperation_364b8af4-cad8-03c2-4998-315e9240f281" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DisposalGroupIncludingDiscontinuedOperationOtherNoncurrentLiabilities" xlink:label="loc_us-gaap_DisposalGroupIncludingDiscontinuedOperationOtherNoncurrentLiabilities_dd0f457c-3cd3-e61e-cd82-b85cdf8d70e8" xlink:type="locator" />
    <link:calculationArc order="1" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesOfDisposalGroupIncludingDiscontinuedOperation_364b8af4-cad8-03c2-4998-315e9240f281" xlink:to="loc_us-gaap_DisposalGroupIncludingDiscontinuedOperationOtherNoncurrentLiabilities_dd0f457c-3cd3-e61e-cd82-b85cdf8d70e8" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_LiabilitiesOfDisposalGroupIncludingDiscontinuedOperationCurrent" xlink:label="loc_us-gaap_LiabilitiesOfDisposalGroupIncludingDiscontinuedOperationCurrent_05b9c2a4-6f85-5413-8af9-df620dfd1b1e" xlink:type="locator" />
    <link:calculationArc order="2" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesOfDisposalGroupIncludingDiscontinuedOperation_364b8af4-cad8-03c2-4998-315e9240f281" xlink:to="loc_us-gaap_LiabilitiesOfDisposalGroupIncludingDiscontinuedOperationCurrent_05b9c2a4-6f85-5413-8af9-df620dfd1b1e" xlink:type="arc" />
  </link:calculationLink>
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/DispositionOfBusiness2016DispositionNarrativeDetails" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/DispositionOfBusiness2017DispositionNarrativeDetails" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/DispositionOfBusiness2017DispositionsDetails" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/DispositionOfBusinessDispositionOfBusinessIncomeLossAttributableToTransformerServicesDetails" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/DispositionOfBusinessIncomeLossAttributableToCatalystServicesDetails" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/DispositionOfBusinessTables" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/DocumentAndEntityInformation" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/EarningsLossPerShare" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/EarningsLossPerShareAntiDilutiveSecuritiesDetails" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/EarningsLossPerShareReconciliationOfBasicAndDilutedEarningsPerShareComputationsDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding" xlink:label="loc_us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding_223fd9c8-68e8-e433-7c40-f98b238e79de" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_WeightedAverageNumberOfSharesOutstandingBasic" xlink:label="loc_us-gaap_WeightedAverageNumberOfSharesOutstandingBasic_86e61cf2-b7b2-e230-65f1-5a2b152f3a30" xlink:type="locator" />
    <link:calculationArc order="1" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding_223fd9c8-68e8-e433-7c40-f98b238e79de" xlink:to="loc_us-gaap_WeightedAverageNumberOfSharesOutstandingBasic_86e61cf2-b7b2-e230-65f1-5a2b152f3a30" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_IncrementalCommonSharesAttributableToShareBasedPaymentArrangements" xlink:label="loc_us-gaap_IncrementalCommonSharesAttributableToShareBasedPaymentArrangements_cee10fe8-a4bb-491c-22f6-69a723d6a718" xlink:type="locator" />
    <link:calculationArc order="2" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding_223fd9c8-68e8-e433-7c40-f98b238e79de" xlink:to="loc_us-gaap_IncrementalCommonSharesAttributableToShareBasedPaymentArrangements_cee10fe8-a4bb-491c-22f6-69a723d6a718" xlink:type="arc" />
  </link:calculationLink>
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/EarningsLossPerShareTables" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/FinancingArrangements" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/FinancingArrangementsNarrativeDetails" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/FinancingArrangementsScheduleOfRedemptionPricesDetails" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/FinancingArrangementsSummaryOfFinancingArrangementsDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_LongTermDebtNoncurrent" xlink:label="loc_us-gaap_LongTermDebtNoncurrent_822b66ff-44a1-e66b-5e0c-09356970a23d" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DebtInstrumentCarryingAmount" xlink:label="loc_us-gaap_DebtInstrumentCarryingAmount_885301e5-debb-a378-50ee-e1d9b92a7437" xlink:type="locator" />
    <link:calculationArc order="1" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LongTermDebtNoncurrent_822b66ff-44a1-e66b-5e0c-09356970a23d" xlink:to="loc_us-gaap_DebtInstrumentCarryingAmount_885301e5-debb-a378-50ee-e1d9b92a7437" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DebtInstrumentUnamortizedDiscountPremiumAndDebtIssuanceCostsNet" xlink:label="loc_us-gaap_DebtInstrumentUnamortizedDiscountPremiumAndDebtIssuanceCostsNet_2a27283b-1aea-485a-d3ce-961b25dfc734" xlink:type="locator" />
    <link:calculationArc order="2" weight="-1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LongTermDebtNoncurrent_822b66ff-44a1-e66b-5e0c-09356970a23d" xlink:to="loc_us-gaap_DebtInstrumentUnamortizedDiscountPremiumAndDebtIssuanceCostsNet_2a27283b-1aea-485a-d3ce-961b25dfc734" xlink:type="arc" />
  </link:calculationLink>
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/FinancingArrangementsTables" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/GoodwillAndOtherIntangibleAssets" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/GoodwillAndOtherIntangibleAssetsChangesToGoodwillDetails" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/GoodwillAndOtherIntangibleAssetsExpectedAmortizationDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsNet" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsNet_49187b45-82fd-7060-b114-79ff249a4331" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseNextTwelveMonths" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseNextTwelveMonths_c918d4cb-4462-72da-1198-39107cb9581b" xlink:type="locator" />
    <link:calculationArc order="1" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsNet_49187b45-82fd-7060-b114-79ff249a4331" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseNextTwelveMonths_c918d4cb-4462-72da-1198-39107cb9581b" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearTwo" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearTwo_e44a1606-1eda-278a-1c39-e2fcbf96f248" xlink:type="locator" />
    <link:calculationArc order="2" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsNet_49187b45-82fd-7060-b114-79ff249a4331" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearTwo_e44a1606-1eda-278a-1c39-e2fcbf96f248" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearThree" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearThree_6a8745e2-e4b9-1a92-2a4b-72abaf326824" xlink:type="locator" />
    <link:calculationArc order="3" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsNet_49187b45-82fd-7060-b114-79ff249a4331" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearThree_6a8745e2-e4b9-1a92-2a4b-72abaf326824" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFour" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFour_ceebb9d8-94b3-173f-0af1-6bad40ca326c" xlink:type="locator" />
    <link:calculationArc order="4" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsNet_49187b45-82fd-7060-b114-79ff249a4331" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFour_ceebb9d8-94b3-173f-0af1-6bad40ca326c" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFive" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFive_b5e743d1-f009-54c0-57f0-4a30eb0e9bab" xlink:type="locator" />
    <link:calculationArc order="5" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsNet_49187b45-82fd-7060-b114-79ff249a4331" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFive_b5e743d1-f009-54c0-57f0-4a30eb0e9bab" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseAfterYearFive" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseAfterYearFive_f98b1772-f2e7-e86d-8181-c87649b7a914" xlink:type="locator" />
    <link:calculationArc order="6" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsNet_49187b45-82fd-7060-b114-79ff249a4331" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseAfterYearFive_f98b1772-f2e7-e86d-8181-c87649b7a914" xlink:type="arc" />
  </link:calculationLink>
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/GoodwillAndOtherIntangibleAssetsFiniteLivedAndIndefiniteLivedIntangibleAssetsDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_IntangibleAssetsNetExcludingGoodwill" xlink:label="loc_us-gaap_IntangibleAssetsNetExcludingGoodwill_1fe06082-076b-052d-6e2e-930afe9d6b2d" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_IntangibleAssetsGrossExcludingGoodwill" xlink:label="loc_us-gaap_IntangibleAssetsGrossExcludingGoodwill_a6de665e-02e5-e3e1-f0df-a5f7155acc66" xlink:type="locator" />
    <link:calculationArc order="1" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IntangibleAssetsNetExcludingGoodwill_1fe06082-076b-052d-6e2e-930afe9d6b2d" xlink:to="loc_us-gaap_IntangibleAssetsGrossExcludingGoodwill_a6de665e-02e5-e3e1-f0df-a5f7155acc66" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsAccumulatedAmortization" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAccumulatedAmortization_c3ed8a56-abe0-6418-c541-e6b647d6318a" xlink:type="locator" />
    <link:calculationArc order="2" weight="-1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IntangibleAssetsNetExcludingGoodwill_1fe06082-076b-052d-6e2e-930afe9d6b2d" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsAccumulatedAmortization_c3ed8a56-abe0-6418-c541-e6b647d6318a" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsNet" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsNet_49187b45-82fd-7060-b114-79ff249a4331" xlink:type="locator" />
    <link:calculationArc order="1" weight="-1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsNet_49187b45-82fd-7060-b114-79ff249a4331" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsAccumulatedAmortization_c3ed8a56-abe0-6418-c541-e6b647d6318a" xlink:type="arc" />
    <link:calculationArc order="2" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsNet_49187b45-82fd-7060-b114-79ff249a4331" xlink:to="loc_us-gaap_IntangibleAssetsGrossExcludingGoodwill_a6de665e-02e5-e3e1-f0df-a5f7155acc66" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsGross" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsGross_5d62e128-f1a1-954f-82e2-1936cb67d793" xlink:type="locator" />
    <link:calculationArc order="3" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsNet_49187b45-82fd-7060-b114-79ff249a4331" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsGross_5d62e128-f1a1-954f-82e2-1936cb67d793" xlink:type="arc" />
  </link:calculationLink>
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/GoodwillAndOtherIntangibleAssetsNarrativeDetails" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/GoodwillAndOtherIntangibleAssetsTables" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/GuarantorAndNonGuarantorSubsidiaries" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/GuarantorAndNonGuarantorSubsidiariesBalanceSheetDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_LiabilitiesAndStockholdersEquity" xlink:label="loc_us-gaap_LiabilitiesAndStockholdersEquity_159dcb00-b17e-17db-7098-be4159799459" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest" xlink:label="loc_us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest_00443492-92dd-7fc1-13b6-792f3e163e73" xlink:type="locator" />
    <link:calculationArc order="1" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquity_159dcb00-b17e-17db-7098-be4159799459" xlink:to="loc_us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest_00443492-92dd-7fc1-13b6-792f3e163e73" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_Liabilities" xlink:label="loc_us-gaap_Liabilities_d8bb821f-d155-9d4e-1738-736b4bf4cb19" xlink:type="locator" />
    <link:calculationArc order="2" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquity_159dcb00-b17e-17db-7098-be4159799459" xlink:to="loc_us-gaap_Liabilities_d8bb821f-d155-9d4e-1738-736b4bf4cb19" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_LiabilitiesCurrent" xlink:label="loc_us-gaap_LiabilitiesCurrent_f5e246cf-e80f-d00b-c8ed-4796aa2df4b4" xlink:type="locator" />
    <link:calculationArc order="1" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Liabilities_d8bb821f-d155-9d4e-1738-736b4bf4cb19" xlink:to="loc_us-gaap_LiabilitiesCurrent_f5e246cf-e80f-d00b-c8ed-4796aa2df4b4" xlink:type="arc" />
    <link:loc xlink:href="clh-20171231.xsd#clh_PayablesToAffiliatesSubsidiariesAndHoldingCompanies" xlink:label="loc_clh_PayablesToAffiliatesSubsidiariesAndHoldingCompanies_b09ee00c-8d10-222c-a813-cb24d90fc3fe" xlink:type="locator" />
    <link:calculationArc order="2" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Liabilities_d8bb821f-d155-9d4e-1738-736b4bf4cb19" xlink:to="loc_clh_PayablesToAffiliatesSubsidiariesAndHoldingCompanies_b09ee00c-8d10-222c-a813-cb24d90fc3fe" xlink:type="arc" />
    <link:loc xlink:href="clh-20171231.xsd#clh_ClosurePostClosureAndRemedialLiabilitiesNet" xlink:label="loc_clh_ClosurePostClosureAndRemedialLiabilitiesNet_29d9e1e2-56f5-7461-c49f-cb24d84d6dcf" xlink:type="locator" />
    <link:calculationArc order="3" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Liabilities_d8bb821f-d155-9d4e-1738-736b4bf4cb19" xlink:to="loc_clh_ClosurePostClosureAndRemedialLiabilitiesNet_29d9e1e2-56f5-7461-c49f-cb24d84d6dcf" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_LongTermDebtNoncurrent" xlink:label="loc_us-gaap_LongTermDebtNoncurrent_822b66ff-44a1-e66b-5e0c-09356970a23d" xlink:type="locator" />
    <link:calculationArc order="4" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Liabilities_d8bb821f-d155-9d4e-1738-736b4bf4cb19" xlink:to="loc_us-gaap_LongTermDebtNoncurrent_822b66ff-44a1-e66b-5e0c-09356970a23d" xlink:type="arc" />
    <link:loc xlink:href="clh-20171231.xsd#clh_DebtPayableToAffiliatesSubsidiariesAndHoldingCompanies" xlink:label="loc_clh_DebtPayableToAffiliatesSubsidiariesAndHoldingCompanies_b323a50b-74d8-09ac-3c23-cb24d8d7f346" xlink:type="locator" />
    <link:calculationArc order="5" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Liabilities_d8bb821f-d155-9d4e-1738-736b4bf4cb19" xlink:to="loc_clh_DebtPayableToAffiliatesSubsidiariesAndHoldingCompanies_b323a50b-74d8-09ac-3c23-cb24d8d7f346" xlink:type="arc" />
    <link:loc xlink:href="clh-20171231.xsd#clh_UnrecognizedTaxBenefitsAndOtherLongTermLiabilitiesNoncurrent" xlink:label="loc_clh_UnrecognizedTaxBenefitsAndOtherLongTermLiabilitiesNoncurrent_12ee4f85-5e55-66d8-2a81-cb24d923daf6" xlink:type="locator" />
    <link:calculationArc order="6" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Liabilities_d8bb821f-d155-9d4e-1738-736b4bf4cb19" xlink:to="loc_clh_UnrecognizedTaxBenefitsAndOtherLongTermLiabilitiesNoncurrent_12ee4f85-5e55-66d8-2a81-cb24d923daf6" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_Assets" xlink:label="loc_us-gaap_Assets_c6057b1d-6685-8249-2051-6c57f3a16a9e" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_CashAndCashEquivalentsAtCarryingValue" xlink:label="loc_us-gaap_CashAndCashEquivalentsAtCarryingValue_07da1db4-2708-4446-4250-1fdd5956185e" xlink:type="locator" />
    <link:calculationArc order="1" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Assets_c6057b1d-6685-8249-2051-6c57f3a16a9e" xlink:to="loc_us-gaap_CashAndCashEquivalentsAtCarryingValue_07da1db4-2708-4446-4250-1fdd5956185e" xlink:type="arc" />
    <link:loc xlink:href="clh-20171231.xsd#clh_ReceivablesFromAffiliatesSubsidiariesAndHoldingCompanies" xlink:label="loc_clh_ReceivablesFromAffiliatesSubsidiariesAndHoldingCompanies_df8d5fb4-d5b9-5fa7-cb78-cb24d8d37210" xlink:type="locator" />
    <link:calculationArc order="2" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Assets_c6057b1d-6685-8249-2051-6c57f3a16a9e" xlink:to="loc_clh_ReceivablesFromAffiliatesSubsidiariesAndHoldingCompanies_df8d5fb4-d5b9-5fa7-cb78-cb24d8d37210" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_AccountsReceivableNetCurrent" xlink:label="loc_us-gaap_AccountsReceivableNetCurrent_dd7775cd-f4ab-5607-9b31-1ee98f605818" xlink:type="locator" />
    <link:calculationArc order="3" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Assets_c6057b1d-6685-8249-2051-6c57f3a16a9e" xlink:to="loc_us-gaap_AccountsReceivableNetCurrent_dd7775cd-f4ab-5607-9b31-1ee98f605818" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_OtherAssetsCurrent" xlink:label="loc_us-gaap_OtherAssetsCurrent_1cb4a384-e314-2300-ad55-c1ed289c8f7a" xlink:type="locator" />
    <link:calculationArc order="4" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Assets_c6057b1d-6685-8249-2051-6c57f3a16a9e" xlink:to="loc_us-gaap_OtherAssetsCurrent_1cb4a384-e314-2300-ad55-c1ed289c8f7a" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_PropertyPlantAndEquipmentNet" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentNet_1944a381-5c4e-ce3c-9111-13ccd1c639db" xlink:type="locator" />
    <link:calculationArc order="5" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Assets_c6057b1d-6685-8249-2051-6c57f3a16a9e" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentNet_1944a381-5c4e-ce3c-9111-13ccd1c639db" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_InvestmentsInAffiliatesSubsidiariesAssociatesAndJointVentures" xlink:label="loc_us-gaap_InvestmentsInAffiliatesSubsidiariesAssociatesAndJointVentures_42d61097-0951-9fd0-ccda-87d8624a6e85" xlink:type="locator" />
    <link:calculationArc order="6" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Assets_c6057b1d-6685-8249-2051-6c57f3a16a9e" xlink:to="loc_us-gaap_InvestmentsInAffiliatesSubsidiariesAssociatesAndJointVentures_42d61097-0951-9fd0-ccda-87d8624a6e85" xlink:type="arc" />
    <link:loc xlink:href="clh-20171231.xsd#clh_DebtReceivableFromAffiliatesSubsidiariesAndHoldingCompanies" xlink:label="loc_clh_DebtReceivableFromAffiliatesSubsidiariesAndHoldingCompanies_cec3060a-caac-57b1-d17d-cb24d8f39f73" xlink:type="locator" />
    <link:calculationArc order="7" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Assets_c6057b1d-6685-8249-2051-6c57f3a16a9e" xlink:to="loc_clh_DebtReceivableFromAffiliatesSubsidiariesAndHoldingCompanies_cec3060a-caac-57b1-d17d-cb24d8f39f73" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_Goodwill" xlink:label="loc_us-gaap_Goodwill_93a64cae-271a-5e6b-8c83-5adf9f941142" xlink:type="locator" />
    <link:calculationArc order="8" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Assets_c6057b1d-6685-8249-2051-6c57f3a16a9e" xlink:to="loc_us-gaap_Goodwill_93a64cae-271a-5e6b-8c83-5adf9f941142" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_IntangibleAssetsNetExcludingGoodwill" xlink:label="loc_us-gaap_IntangibleAssetsNetExcludingGoodwill_1fe06082-076b-052d-6e2e-930afe9d6b2d" xlink:type="locator" />
    <link:calculationArc order="9" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Assets_c6057b1d-6685-8249-2051-6c57f3a16a9e" xlink:to="loc_us-gaap_IntangibleAssetsNetExcludingGoodwill_1fe06082-076b-052d-6e2e-930afe9d6b2d" xlink:type="arc" />
    <link:loc xlink:href="clh-20171231.xsd#clh_DeferredFinancingCostsandOtherAssets" xlink:label="loc_clh_DeferredFinancingCostsandOtherAssets_dfef4c39-1936-824d-7eda-32a6cedbedff" xlink:type="locator" />
    <link:calculationArc order="10" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Assets_c6057b1d-6685-8249-2051-6c57f3a16a9e" xlink:to="loc_clh_DeferredFinancingCostsandOtherAssets_dfef4c39-1936-824d-7eda-32a6cedbedff" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_MarketableSecuritiesCurrent" xlink:label="loc_us-gaap_MarketableSecuritiesCurrent_77be6853-2f03-c976-4472-a91565f93300" xlink:type="locator" />
    <link:calculationArc order="11" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Assets_c6057b1d-6685-8249-2051-6c57f3a16a9e" xlink:to="loc_us-gaap_MarketableSecuritiesCurrent_77be6853-2f03-c976-4472-a91565f93300" xlink:type="arc" />
  </link:calculationLink>
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/GuarantorAndNonGuarantorSubsidiariesCashFlowsDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_NetCashProvidedByUsedInFinancingActivities" xlink:label="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_deb49b68-c030-7624-a39d-ea301caa5dbf" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_IncreaseDecreaseInOutstandingChecksFinancingActivities" xlink:label="loc_us-gaap_IncreaseDecreaseInOutstandingChecksFinancingActivities_e38a62e1-6fbb-f0a4-0eb9-c88c8076f811" xlink:type="locator" />
    <link:calculationArc order="1" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_deb49b68-c030-7624-a39d-ea301caa5dbf" xlink:to="loc_us-gaap_IncreaseDecreaseInOutstandingChecksFinancingActivities_e38a62e1-6fbb-f0a4-0eb9-c88c8076f811" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_PaymentsRelatedToTaxWithholdingForShareBasedCompensation" xlink:label="loc_us-gaap_PaymentsRelatedToTaxWithholdingForShareBasedCompensation_6d67f644-e190-e5ce-9449-e00a27ad7771" xlink:type="locator" />
    <link:calculationArc order="2" weight="-1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_deb49b68-c030-7624-a39d-ea301caa5dbf" xlink:to="loc_us-gaap_PaymentsRelatedToTaxWithholdingForShareBasedCompensation_6d67f644-e190-e5ce-9449-e00a27ad7771" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_PaymentsForRepurchaseOfCommonStock" xlink:label="loc_us-gaap_PaymentsForRepurchaseOfCommonStock_8a1490c4-32d9-5132-1fe2-2675a45abdae" xlink:type="locator" />
    <link:calculationArc order="3" weight="-1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_deb49b68-c030-7624-a39d-ea301caa5dbf" xlink:to="loc_us-gaap_PaymentsForRepurchaseOfCommonStock_8a1490c4-32d9-5132-1fe2-2675a45abdae" xlink:type="arc" />
    <link:loc xlink:href="clh-20171231.xsd#clh_IntercompanyFinancing" xlink:label="loc_clh_IntercompanyFinancing_4aeed874-1504-661e-7680-cb24d910658e" xlink:type="locator" />
    <link:calculationArc order="4" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_deb49b68-c030-7624-a39d-ea301caa5dbf" xlink:to="loc_clh_IntercompanyFinancing_4aeed874-1504-661e-7680-cb24d910658e" xlink:type="arc" />
    <link:loc xlink:href="clh-20171231.xsd#clh_IntercompanyDebtFinancing" xlink:label="loc_clh_IntercompanyDebtFinancing_ab05669f-d180-cb09-00c8-cb24d8f2ee24" xlink:type="locator" />
    <link:calculationArc order="5" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_deb49b68-c030-7624-a39d-ea301caa5dbf" xlink:to="loc_clh_IntercompanyDebtFinancing_ab05669f-d180-cb09-00c8-cb24d8f2ee24" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ExcessTaxBenefitFromShareBasedCompensationFinancingActivities" xlink:label="loc_us-gaap_ExcessTaxBenefitFromShareBasedCompensationFinancingActivities_cf22d061-7c46-e185-574b-89b7ef77509e" xlink:type="locator" />
    <link:calculationArc order="6" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_deb49b68-c030-7624-a39d-ea301caa5dbf" xlink:to="loc_us-gaap_ExcessTaxBenefitFromShareBasedCompensationFinancingActivities_cf22d061-7c46-e185-574b-89b7ef77509e" xlink:type="arc" />
    <link:loc xlink:href="clh-20171231.xsd#clh_RepaymentOfCapitalLeaseObligation" xlink:label="loc_clh_RepaymentOfCapitalLeaseObligation_9e87d6aa-a50a-5812-8b0a-cb24d84cd00c" xlink:type="locator" />
    <link:calculationArc order="7" weight="-1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_deb49b68-c030-7624-a39d-ea301caa5dbf" xlink:to="loc_clh_RepaymentOfCapitalLeaseObligation_9e87d6aa-a50a-5812-8b0a-cb24d84cd00c" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ProceedsFromStockOptionsExercised" xlink:label="loc_us-gaap_ProceedsFromStockOptionsExercised_d04df344-47da-0222-79d0-99b7d739fd60" xlink:type="locator" />
    <link:calculationArc order="8" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_deb49b68-c030-7624-a39d-ea301caa5dbf" xlink:to="loc_us-gaap_ProceedsFromStockOptionsExercised_d04df344-47da-0222-79d0-99b7d739fd60" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_PaymentsOfFinancingCosts" xlink:label="loc_us-gaap_PaymentsOfFinancingCosts_7b8a0794-7d87-21cc-a206-45c556522750" xlink:type="locator" />
    <link:calculationArc order="9" weight="-1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_deb49b68-c030-7624-a39d-ea301caa5dbf" xlink:to="loc_us-gaap_PaymentsOfFinancingCosts_7b8a0794-7d87-21cc-a206-45c556522750" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ProceedsFromIssuanceOfLongTermDebt" xlink:label="loc_us-gaap_ProceedsFromIssuanceOfLongTermDebt_e5f1c7a4-b42a-8461-2001-b1f20e51b257" xlink:type="locator" />
    <link:calculationArc order="10" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_deb49b68-c030-7624-a39d-ea301caa5dbf" xlink:to="loc_us-gaap_ProceedsFromIssuanceOfLongTermDebt_e5f1c7a4-b42a-8461-2001-b1f20e51b257" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_RepaymentsOfLongTermDebt" xlink:label="loc_us-gaap_RepaymentsOfLongTermDebt_2b72fe5f-3c0e-d5e0-8e5c-ad01818e58e5" xlink:type="locator" />
    <link:calculationArc order="11" weight="-1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_deb49b68-c030-7624-a39d-ea301caa5dbf" xlink:to="loc_us-gaap_RepaymentsOfLongTermDebt_2b72fe5f-3c0e-d5e0-8e5c-ad01818e58e5" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_PaymentsOfDebtExtinguishmentCosts" xlink:label="loc_us-gaap_PaymentsOfDebtExtinguishmentCosts_2afa112f-8746-a6f0-c674-adbee2f9fa7d" xlink:type="locator" />
    <link:calculationArc order="12" weight="-1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_deb49b68-c030-7624-a39d-ea301caa5dbf" xlink:to="loc_us-gaap_PaymentsOfDebtExtinguishmentCosts_2afa112f-8746-a6f0-c674-adbee2f9fa7d" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ProceedsFromIssuanceOfSeniorLongTermDebt" xlink:label="loc_us-gaap_ProceedsFromIssuanceOfSeniorLongTermDebt_bad9c157-2ff8-61fa-9513-64af29da849d" xlink:type="locator" />
    <link:calculationArc order="13" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_deb49b68-c030-7624-a39d-ea301caa5dbf" xlink:to="loc_us-gaap_ProceedsFromIssuanceOfSeniorLongTermDebt_bad9c157-2ff8-61fa-9513-64af29da849d" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_NetCashProvidedByUsedInInvestingActivities" xlink:label="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_70319186-e7bd-7189-88d2-eba26fb93350" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_PaymentsToAcquirePropertyPlantAndEquipment" xlink:label="loc_us-gaap_PaymentsToAcquirePropertyPlantAndEquipment_fee12b15-6b42-6245-2e2f-ff030b98332c" xlink:type="locator" />
    <link:calculationArc order="1" weight="-1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_70319186-e7bd-7189-88d2-eba26fb93350" xlink:to="loc_us-gaap_PaymentsToAcquirePropertyPlantAndEquipment_fee12b15-6b42-6245-2e2f-ff030b98332c" xlink:type="arc" />
    <link:loc xlink:href="clh-20171231.xsd#clh_ProceedsFromSalesOfFixedAssetsAndAssetsHeldForSale" xlink:label="loc_clh_ProceedsFromSalesOfFixedAssetsAndAssetsHeldForSale_a6459952-9d42-ca44-a1b1-32a6cf439378" xlink:type="locator" />
    <link:calculationArc order="2" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_70319186-e7bd-7189-88d2-eba26fb93350" xlink:to="loc_clh_ProceedsFromSalesOfFixedAssetsAndAssetsHeldForSale_a6459952-9d42-ca44-a1b1-32a6cf439378" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_PaymentsToAcquireBusinessesNetOfCashAcquired" xlink:label="loc_us-gaap_PaymentsToAcquireBusinessesNetOfCashAcquired_9d35c912-5b2d-89f7-eeb3-812a0511db5e" xlink:type="locator" />
    <link:calculationArc order="3" weight="-1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_70319186-e7bd-7189-88d2-eba26fb93350" xlink:to="loc_us-gaap_PaymentsToAcquireBusinessesNetOfCashAcquired_9d35c912-5b2d-89f7-eeb3-812a0511db5e" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ProceedsFromDivestitureOfBusinesses" xlink:label="loc_us-gaap_ProceedsFromDivestitureOfBusinesses_1b49b102-31cf-7322-08b6-a997061a74c1" xlink:type="locator" />
    <link:calculationArc order="4" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_70319186-e7bd-7189-88d2-eba26fb93350" xlink:to="loc_us-gaap_ProceedsFromDivestitureOfBusinesses_1b49b102-31cf-7322-08b6-a997061a74c1" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_PaymentsToAcquireIntangibleAssets" xlink:label="loc_us-gaap_PaymentsToAcquireIntangibleAssets_3be9d1aa-8098-ddda-91ce-5e44ee6678ae" xlink:type="locator" />
    <link:calculationArc order="5" weight="-1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_70319186-e7bd-7189-88d2-eba26fb93350" xlink:to="loc_us-gaap_PaymentsToAcquireIntangibleAssets_3be9d1aa-8098-ddda-91ce-5e44ee6678ae" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_PaymentsToAcquireAvailableForSaleSecurities" xlink:label="loc_us-gaap_PaymentsToAcquireAvailableForSaleSecurities_9cebbd9b-269e-5a19-54b8-1c32e2660d83" xlink:type="locator" />
    <link:calculationArc order="6" weight="-1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_70319186-e7bd-7189-88d2-eba26fb93350" xlink:to="loc_us-gaap_PaymentsToAcquireAvailableForSaleSecurities_9cebbd9b-269e-5a19-54b8-1c32e2660d83" xlink:type="arc" />
    <link:loc xlink:href="clh-20171231.xsd#clh_IntercompanyInvesting" xlink:label="loc_clh_IntercompanyInvesting_3a6100ce-c3a8-85dd-9d0b-cb24d9119f58" xlink:type="locator" />
    <link:calculationArc order="7" weight="-1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_70319186-e7bd-7189-88d2-eba26fb93350" xlink:to="loc_clh_IntercompanyInvesting_3a6100ce-c3a8-85dd-9d0b-cb24d9119f58" xlink:type="arc" />
    <link:loc xlink:href="clh-20171231.xsd#clh_IntercompanyDebtInvesting" xlink:label="loc_clh_IntercompanyDebtInvesting_019f98f6-318c-d2c2-316a-cb24d8dac9b2" xlink:type="locator" />
    <link:calculationArc order="8" weight="-1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_70319186-e7bd-7189-88d2-eba26fb93350" xlink:to="loc_clh_IntercompanyDebtInvesting_019f98f6-318c-d2c2-316a-cb24d8dac9b2" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_PaymentsToAcquireAdditionalInterestInSubsidiaries" xlink:label="loc_us-gaap_PaymentsToAcquireAdditionalInterestInSubsidiaries_5f7d7f74-45c4-afb3-6117-ea0cc133d19b" xlink:type="locator" />
    <link:calculationArc order="9" weight="-1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_70319186-e7bd-7189-88d2-eba26fb93350" xlink:to="loc_us-gaap_PaymentsToAcquireAdditionalInterestInSubsidiaries_5f7d7f74-45c4-afb3-6117-ea0cc133d19b" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ProceedsFromSaleOfLongtermInvestments" xlink:label="loc_us-gaap_ProceedsFromSaleOfLongtermInvestments_d57b44f7-babf-c2f5-85dc-86f27625659f" xlink:type="locator" />
    <link:calculationArc order="10" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_70319186-e7bd-7189-88d2-eba26fb93350" xlink:to="loc_us-gaap_ProceedsFromSaleOfLongtermInvestments_d57b44f7-babf-c2f5-85dc-86f27625659f" xlink:type="arc" />
  </link:calculationLink>
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/GuarantorAndNonGuarantorSubsidiariesIncomeStatementDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments" xlink:label="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments_0eb47183-f513-314d-ceda-ee2412d9eee8" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_OperatingIncomeLoss" xlink:label="loc_us-gaap_OperatingIncomeLoss_9894e895-7695-402a-9f03-08d60b7373b8" xlink:type="locator" />
    <link:calculationArc order="1" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments_0eb47183-f513-314d-ceda-ee2412d9eee8" xlink:to="loc_us-gaap_OperatingIncomeLoss_9894e895-7695-402a-9f03-08d60b7373b8" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_OtherNonoperatingIncomeExpense" xlink:label="loc_us-gaap_OtherNonoperatingIncomeExpense_250c3b2f-7db5-7088-68cc-1dd831a2c2d7" xlink:type="locator" />
    <link:calculationArc order="2" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments_0eb47183-f513-314d-ceda-ee2412d9eee8" xlink:to="loc_us-gaap_OtherNonoperatingIncomeExpense_250c3b2f-7db5-7088-68cc-1dd831a2c2d7" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_GainsLossesOnExtinguishmentOfDebt" xlink:label="loc_us-gaap_GainsLossesOnExtinguishmentOfDebt_3db65903-3171-d63c-a688-532ba00b8108" xlink:type="locator" />
    <link:calculationArc order="3" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments_0eb47183-f513-314d-ceda-ee2412d9eee8" xlink:to="loc_us-gaap_GainsLossesOnExtinguishmentOfDebt_3db65903-3171-d63c-a688-532ba00b8108" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_GainLossOnSaleOfBusiness" xlink:label="loc_us-gaap_GainLossOnSaleOfBusiness_0427ef0c-6a82-1061-c648-71b3a1a70634" xlink:type="locator" />
    <link:calculationArc order="4" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments_0eb47183-f513-314d-ceda-ee2412d9eee8" xlink:to="loc_us-gaap_GainLossOnSaleOfBusiness_0427ef0c-6a82-1061-c648-71b3a1a70634" xlink:type="arc" />
    <link:loc xlink:href="clh-20171231.xsd#clh_InterestExpenseNet" xlink:label="loc_clh_InterestExpenseNet_7994a7f2-68fc-0a40-d859-32a6ceb260ef" xlink:type="locator" />
    <link:calculationArc order="5" weight="-1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments_0eb47183-f513-314d-ceda-ee2412d9eee8" xlink:to="loc_clh_InterestExpenseNet_7994a7f2-68fc-0a40-d859-32a6ceb260ef" xlink:type="arc" />
    <link:loc xlink:href="clh-20171231.xsd#clh_IncomeLossFromAffiliatesSubsidiariesAndHoldingCompany" xlink:label="loc_clh_IncomeLossFromAffiliatesSubsidiariesAndHoldingCompany_c794806f-d7f1-7e9c-fd0d-cb24d8e35ff7" xlink:type="locator" />
    <link:calculationArc order="6" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments_0eb47183-f513-314d-ceda-ee2412d9eee8" xlink:to="loc_clh_IncomeLossFromAffiliatesSubsidiariesAndHoldingCompany_c794806f-d7f1-7e9c-fd0d-cb24d8e35ff7" xlink:type="arc" />
    <link:loc xlink:href="clh-20171231.xsd#clh_NetInterestIncomeFromAffiliatesSubsidiariesAndHoldingCompany" xlink:label="loc_clh_NetInterestIncomeFromAffiliatesSubsidiariesAndHoldingCompany_b3c09c0e-0c5c-ad27-034f-cb24d903310a" xlink:type="locator" />
    <link:calculationArc order="7" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments_0eb47183-f513-314d-ceda-ee2412d9eee8" xlink:to="loc_clh_NetInterestIncomeFromAffiliatesSubsidiariesAndHoldingCompany_b3c09c0e-0c5c-ad27-034f-cb24d903310a" xlink:type="arc" />
  </link:calculationLink>
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/GuarantorAndNonGuarantorSubsidiariesTables" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/IncomeTaxes" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/IncomeTaxesAdditionalInformationDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DeferredTaxAssetsValuationAllowance" xlink:label="loc_us-gaap_DeferredTaxAssetsValuationAllowance_46929883-d93f-69b0-5ded-4c800feeb57f" xlink:type="locator" />
    <link:loc xlink:href="clh-20171231.xsd#clh_ValuationAllowanceAmountForeignTaxCredits" xlink:label="loc_clh_ValuationAllowanceAmountForeignTaxCredits_42e46a6d-5278-7d96-888c-32a6ce8646e6" xlink:type="locator" />
    <link:calculationArc order="1" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DeferredTaxAssetsValuationAllowance_46929883-d93f-69b0-5ded-4c800feeb57f" xlink:to="loc_clh_ValuationAllowanceAmountForeignTaxCredits_42e46a6d-5278-7d96-888c-32a6ce8646e6" xlink:type="arc" />
    <link:loc xlink:href="clh-20171231.xsd#clh_ValuationAllowanceDeferredTaxAssetFederalNetOperatingLossCarryforwards" xlink:label="loc_clh_ValuationAllowanceDeferredTaxAssetFederalNetOperatingLossCarryforwards_0c3aae54-663a-6ec6-9f9c-32a6ceb04914" xlink:type="locator" />
    <link:calculationArc order="2" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DeferredTaxAssetsValuationAllowance_46929883-d93f-69b0-5ded-4c800feeb57f" xlink:to="loc_clh_ValuationAllowanceDeferredTaxAssetFederalNetOperatingLossCarryforwards_0c3aae54-663a-6ec6-9f9c-32a6ceb04914" xlink:type="arc" />
    <link:loc xlink:href="clh-20171231.xsd#clh_ValuationAllowanceAmountStateNetOperatingLoss" xlink:label="loc_clh_ValuationAllowanceAmountStateNetOperatingLoss_b8ac481a-3d1c-e1d2-29ca-32a6cefacefd" xlink:type="locator" />
    <link:calculationArc order="3" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DeferredTaxAssetsValuationAllowance_46929883-d93f-69b0-5ded-4c800feeb57f" xlink:to="loc_clh_ValuationAllowanceAmountStateNetOperatingLoss_b8ac481a-3d1c-e1d2-29ca-32a6cefacefd" xlink:type="arc" />
    <link:loc xlink:href="clh-20171231.xsd#clh_ValuationAllowanceAmountForeignNetOperatingLoss" xlink:label="loc_clh_ValuationAllowanceAmountForeignNetOperatingLoss_ab47ed3c-f58b-7509-d139-32a6cf25e010" xlink:type="locator" />
    <link:calculationArc order="4" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DeferredTaxAssetsValuationAllowance_46929883-d93f-69b0-5ded-4c800feeb57f" xlink:to="loc_clh_ValuationAllowanceAmountForeignNetOperatingLoss_ab47ed3c-f58b-7509-d139-32a6cf25e010" xlink:type="arc" />
    <link:loc xlink:href="clh-20171231.xsd#clh_ValuationAllowanceAmountDeferredTaxAssetsofSubsidiary" xlink:label="loc_clh_ValuationAllowanceAmountDeferredTaxAssetsofSubsidiary_19c01b0c-0573-99db-a4f7-32a6cdfa242e" xlink:type="locator" />
    <link:calculationArc order="5" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DeferredTaxAssetsValuationAllowance_46929883-d93f-69b0-5ded-4c800feeb57f" xlink:to="loc_clh_ValuationAllowanceAmountDeferredTaxAssetsofSubsidiary_19c01b0c-0573-99db-a4f7-32a6cdfa242e" xlink:type="arc" />
  </link:calculationLink>
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/IncomeTaxesDeferredTaxAssetsAndLiabilitiesDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DeferredTaxLiabilities" xlink:label="loc_us-gaap_DeferredTaxLiabilities_644ceb1c-07ef-6a89-f014-9d7b5dfbc918" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DeferredTaxAssetsValuationAllowance" xlink:label="loc_us-gaap_DeferredTaxAssetsValuationAllowance_46929883-d93f-69b0-5ded-4c800feeb57f" xlink:type="locator" />
    <link:calculationArc order="1" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DeferredTaxLiabilities_644ceb1c-07ef-6a89-f014-9d7b5dfbc918" xlink:to="loc_us-gaap_DeferredTaxAssetsValuationAllowance_46929883-d93f-69b0-5ded-4c800feeb57f" xlink:type="arc" />
    <link:loc xlink:href="clh-20171231.xsd#clh_DeferredTaxLiabilitiesNetBeforeValuationAllowance" xlink:label="loc_clh_DeferredTaxLiabilitiesNetBeforeValuationAllowance_f8bc94ea-885e-d80d-1925-32a6cdf490ce" xlink:type="locator" />
    <link:calculationArc order="2" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DeferredTaxLiabilities_644ceb1c-07ef-6a89-f014-9d7b5dfbc918" xlink:to="loc_clh_DeferredTaxLiabilitiesNetBeforeValuationAllowance_f8bc94ea-885e-d80d-1925-32a6cdf490ce" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DeferredTaxAssetsNet" xlink:label="loc_us-gaap_DeferredTaxAssetsNet_d74724c2-178d-7f3f-8e86-5f5ba690672c" xlink:type="locator" />
    <link:calculationArc order="1" weight="-1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_clh_DeferredTaxLiabilitiesNetBeforeValuationAllowance_f8bc94ea-885e-d80d-1925-32a6cdf490ce" xlink:to="loc_us-gaap_DeferredTaxAssetsNet_d74724c2-178d-7f3f-8e86-5f5ba690672c" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DeferredTaxAssetsTaxDeferredExpenseReservesAndAccrualsAllowanceForDoubtfulAccounts" xlink:label="loc_us-gaap_DeferredTaxAssetsTaxDeferredExpenseReservesAndAccrualsAllowanceForDoubtfulAccounts_c4877654-c7dc-bad7-b5da-7d794edd1d08" xlink:type="locator" />
    <link:calculationArc order="1" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DeferredTaxAssetsNet_d74724c2-178d-7f3f-8e86-5f5ba690672c" xlink:to="loc_us-gaap_DeferredTaxAssetsTaxDeferredExpenseReservesAndAccrualsAllowanceForDoubtfulAccounts_c4877654-c7dc-bad7-b5da-7d794edd1d08" xlink:type="arc" />
    <link:loc xlink:href="clh-20171231.xsd#clh_DeferredTaxAssetsClosurePostClosureAndRemedialLiabilities" xlink:label="loc_clh_DeferredTaxAssetsClosurePostClosureAndRemedialLiabilities_afab5a33-50bd-dea1-8a63-32a6cee02bb3" xlink:type="locator" />
    <link:calculationArc order="2" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DeferredTaxAssetsNet_d74724c2-178d-7f3f-8e86-5f5ba690672c" xlink:to="loc_clh_DeferredTaxAssetsClosurePostClosureAndRemedialLiabilities_afab5a33-50bd-dea1-8a63-32a6cee02bb3" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DeferredTaxAssetsTaxDeferredExpenseReservesAndAccrualsAccruedLiabilities" xlink:label="loc_us-gaap_DeferredTaxAssetsTaxDeferredExpenseReservesAndAccrualsAccruedLiabilities_21d3fdc5-0c57-3147-2d98-67c225186166" xlink:type="locator" />
    <link:calculationArc order="3" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DeferredTaxAssetsNet_d74724c2-178d-7f3f-8e86-5f5ba690672c" xlink:to="loc_us-gaap_DeferredTaxAssetsTaxDeferredExpenseReservesAndAccrualsAccruedLiabilities_21d3fdc5-0c57-3147-2d98-67c225186166" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DeferredTaxAssetsTaxDeferredExpenseCompensationAndBenefitsEmployeeCompensation" xlink:label="loc_us-gaap_DeferredTaxAssetsTaxDeferredExpenseCompensationAndBenefitsEmployeeCompensation_b83ae405-2db3-2611-a552-535d0f152906" xlink:type="locator" />
    <link:calculationArc order="4" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DeferredTaxAssetsNet_d74724c2-178d-7f3f-8e86-5f5ba690672c" xlink:to="loc_us-gaap_DeferredTaxAssetsTaxDeferredExpenseCompensationAndBenefitsEmployeeCompensation_b83ae405-2db3-2611-a552-535d0f152906" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DeferredTaxAssetsOperatingLossCarryforwards" xlink:label="loc_us-gaap_DeferredTaxAssetsOperatingLossCarryforwards_3541201a-a025-b00d-aec1-2cb167bdef44" xlink:type="locator" />
    <link:calculationArc order="5" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DeferredTaxAssetsNet_d74724c2-178d-7f3f-8e86-5f5ba690672c" xlink:to="loc_us-gaap_DeferredTaxAssetsOperatingLossCarryforwards_3541201a-a025-b00d-aec1-2cb167bdef44" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DeferredTaxAssetsTaxCreditCarryforwards" xlink:label="loc_us-gaap_DeferredTaxAssetsTaxCreditCarryforwards_c63966d8-8cd7-cadc-7cf6-f799677021d3" xlink:type="locator" />
    <link:calculationArc order="6" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DeferredTaxAssetsNet_d74724c2-178d-7f3f-8e86-5f5ba690672c" xlink:to="loc_us-gaap_DeferredTaxAssetsTaxCreditCarryforwards_c63966d8-8cd7-cadc-7cf6-f799677021d3" xlink:type="arc" />
    <link:loc xlink:href="clh-20171231.xsd#clh_DeferredTaxAssetsUncertainTaxPositionsAccruedInterestAndFederalBenefit" xlink:label="loc_clh_DeferredTaxAssetsUncertainTaxPositionsAccruedInterestAndFederalBenefit_52e908f2-5316-cd80-a59e-32a6cd0ec9c1" xlink:type="locator" />
    <link:calculationArc order="7" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DeferredTaxAssetsNet_d74724c2-178d-7f3f-8e86-5f5ba690672c" xlink:to="loc_clh_DeferredTaxAssetsUncertainTaxPositionsAccruedInterestAndFederalBenefit_52e908f2-5316-cd80-a59e-32a6cd0ec9c1" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DeferredTaxAssetsTaxDeferredExpenseCompensationAndBenefitsShareBasedCompensationCost" xlink:label="loc_us-gaap_DeferredTaxAssetsTaxDeferredExpenseCompensationAndBenefitsShareBasedCompensationCost_f7e9e6da-5d57-5f97-5d33-52f319506ef0" xlink:type="locator" />
    <link:calculationArc order="8" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DeferredTaxAssetsNet_d74724c2-178d-7f3f-8e86-5f5ba690672c" xlink:to="loc_us-gaap_DeferredTaxAssetsTaxDeferredExpenseCompensationAndBenefitsShareBasedCompensationCost_f7e9e6da-5d57-5f97-5d33-52f319506ef0" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DeferredTaxAssetsOther" xlink:label="loc_us-gaap_DeferredTaxAssetsOther_91623f44-5f42-408a-f7b7-7a4698afab83" xlink:type="locator" />
    <link:calculationArc order="9" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DeferredTaxAssetsNet_d74724c2-178d-7f3f-8e86-5f5ba690672c" xlink:to="loc_us-gaap_DeferredTaxAssetsOther_91623f44-5f42-408a-f7b7-7a4698afab83" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DeferredIncomeTaxLiabilities" xlink:label="loc_us-gaap_DeferredIncomeTaxLiabilities_bbf9fd06-b461-3f65-8882-6e322d99a60b" xlink:type="locator" />
    <link:calculationArc order="2" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_clh_DeferredTaxLiabilitiesNetBeforeValuationAllowance_f8bc94ea-885e-d80d-1925-32a6cdf490ce" xlink:to="loc_us-gaap_DeferredIncomeTaxLiabilities_bbf9fd06-b461-3f65-8882-6e322d99a60b" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DeferredTaxLiabilitiesPropertyPlantAndEquipment" xlink:label="loc_us-gaap_DeferredTaxLiabilitiesPropertyPlantAndEquipment_dde5eeca-2b71-60e2-a05c-fb2f2f5703af" xlink:type="locator" />
    <link:calculationArc order="1" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DeferredIncomeTaxLiabilities_bbf9fd06-b461-3f65-8882-6e322d99a60b" xlink:to="loc_us-gaap_DeferredTaxLiabilitiesPropertyPlantAndEquipment_dde5eeca-2b71-60e2-a05c-fb2f2f5703af" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DeferredTaxLiabilitiesGoodwillAndIntangibleAssetsIntangibleAssets" xlink:label="loc_us-gaap_DeferredTaxLiabilitiesGoodwillAndIntangibleAssetsIntangibleAssets_d1de4f5a-e70f-c355-7179-89a9064c7b88" xlink:type="locator" />
    <link:calculationArc order="2" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DeferredIncomeTaxLiabilities_bbf9fd06-b461-3f65-8882-6e322d99a60b" xlink:to="loc_us-gaap_DeferredTaxLiabilitiesGoodwillAndIntangibleAssetsIntangibleAssets_d1de4f5a-e70f-c355-7179-89a9064c7b88" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DeferredTaxLiabilitiesPrepaidExpenses" xlink:label="loc_us-gaap_DeferredTaxLiabilitiesPrepaidExpenses_9fb66626-9640-44ad-4417-4000d4376288" xlink:type="locator" />
    <link:calculationArc order="3" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DeferredIncomeTaxLiabilities_bbf9fd06-b461-3f65-8882-6e322d99a60b" xlink:to="loc_us-gaap_DeferredTaxLiabilitiesPrepaidExpenses_9fb66626-9640-44ad-4417-4000d4376288" xlink:type="arc" />
  </link:calculationLink>
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/IncomeTaxesProvisionForTaxExpenseDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments" xlink:label="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments_0eb47183-f513-314d-ceda-ee2412d9eee8" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesDomestic" xlink:label="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesDomestic_684e73bc-c774-15b7-cfc4-307e06892c2e" xlink:type="locator" />
    <link:calculationArc order="1" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments_0eb47183-f513-314d-ceda-ee2412d9eee8" xlink:to="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesDomestic_684e73bc-c774-15b7-cfc4-307e06892c2e" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesForeign" xlink:label="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesForeign_77aad584-eda7-6ab9-9bf4-262b9a6dd394" xlink:type="locator" />
    <link:calculationArc order="2" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments_0eb47183-f513-314d-ceda-ee2412d9eee8" xlink:to="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesForeign_77aad584-eda7-6ab9-9bf4-262b9a6dd394" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_CurrentIncomeTaxExpenseBenefit" xlink:label="loc_us-gaap_CurrentIncomeTaxExpenseBenefit_d2250640-c0ab-3b70-41b7-136d9a4aad78" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_CurrentFederalTaxExpenseBenefit" xlink:label="loc_us-gaap_CurrentFederalTaxExpenseBenefit_36ba223a-0466-98b6-2d31-f243492419f9" xlink:type="locator" />
    <link:calculationArc order="1" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_CurrentIncomeTaxExpenseBenefit_d2250640-c0ab-3b70-41b7-136d9a4aad78" xlink:to="loc_us-gaap_CurrentFederalTaxExpenseBenefit_36ba223a-0466-98b6-2d31-f243492419f9" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_CurrentStateAndLocalTaxExpenseBenefit" xlink:label="loc_us-gaap_CurrentStateAndLocalTaxExpenseBenefit_10028fc1-eee3-03f5-6f20-ff5d85e3c0b2" xlink:type="locator" />
    <link:calculationArc order="2" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_CurrentIncomeTaxExpenseBenefit_d2250640-c0ab-3b70-41b7-136d9a4aad78" xlink:to="loc_us-gaap_CurrentStateAndLocalTaxExpenseBenefit_10028fc1-eee3-03f5-6f20-ff5d85e3c0b2" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_CurrentForeignTaxExpenseBenefit" xlink:label="loc_us-gaap_CurrentForeignTaxExpenseBenefit_7d48046d-7441-0899-53b0-aaa1e573540a" xlink:type="locator" />
    <link:calculationArc order="3" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_CurrentIncomeTaxExpenseBenefit_d2250640-c0ab-3b70-41b7-136d9a4aad78" xlink:to="loc_us-gaap_CurrentForeignTaxExpenseBenefit_7d48046d-7441-0899-53b0-aaa1e573540a" xlink:type="arc" />
    <link:loc xlink:href="clh-20171231.xsd#clh_DeferredIncomeTaxExpenseBenefitNetOfDiscontinuedOperations" xlink:label="loc_clh_DeferredIncomeTaxExpenseBenefitNetOfDiscontinuedOperations_32ed1d6b-3788-96f2-e692-32a6cede5676" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DeferredFederalIncomeTaxExpenseBenefit" xlink:label="loc_us-gaap_DeferredFederalIncomeTaxExpenseBenefit_15bb8413-7c16-05ff-0f24-330007bd87a4" xlink:type="locator" />
    <link:calculationArc order="1" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_clh_DeferredIncomeTaxExpenseBenefitNetOfDiscontinuedOperations_32ed1d6b-3788-96f2-e692-32a6cede5676" xlink:to="loc_us-gaap_DeferredFederalIncomeTaxExpenseBenefit_15bb8413-7c16-05ff-0f24-330007bd87a4" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DeferredStateAndLocalIncomeTaxExpenseBenefit" xlink:label="loc_us-gaap_DeferredStateAndLocalIncomeTaxExpenseBenefit_40691c72-4a6d-af64-c37e-f5abe38c6165" xlink:type="locator" />
    <link:calculationArc order="2" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_clh_DeferredIncomeTaxExpenseBenefitNetOfDiscontinuedOperations_32ed1d6b-3788-96f2-e692-32a6cede5676" xlink:to="loc_us-gaap_DeferredStateAndLocalIncomeTaxExpenseBenefit_40691c72-4a6d-af64-c37e-f5abe38c6165" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DeferredForeignIncomeTaxExpenseBenefit" xlink:label="loc_us-gaap_DeferredForeignIncomeTaxExpenseBenefit_67cd26b3-6ceb-499c-0dd8-da28cd1ddfc3" xlink:type="locator" />
    <link:calculationArc order="3" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_clh_DeferredIncomeTaxExpenseBenefitNetOfDiscontinuedOperations_32ed1d6b-3788-96f2-e692-32a6cede5676" xlink:to="loc_us-gaap_DeferredForeignIncomeTaxExpenseBenefit_67cd26b3-6ceb-499c-0dd8-da28cd1ddfc3" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_IncomeTaxExpenseBenefit" xlink:label="loc_us-gaap_IncomeTaxExpenseBenefit_78b7d85e-8366-fe6d-cb1f-faac5a041b79" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_IncomeTaxReconciliationIncomeTaxExpenseBenefitAtFederalStatutoryIncomeTaxRate" xlink:label="loc_us-gaap_IncomeTaxReconciliationIncomeTaxExpenseBenefitAtFederalStatutoryIncomeTaxRate_16f0a3f7-750c-3f06-7b05-d8ae2aae120b" xlink:type="locator" />
    <link:calculationArc order="1" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IncomeTaxExpenseBenefit_78b7d85e-8366-fe6d-cb1f-faac5a041b79" xlink:to="loc_us-gaap_IncomeTaxReconciliationIncomeTaxExpenseBenefitAtFederalStatutoryIncomeTaxRate_16f0a3f7-750c-3f06-7b05-d8ae2aae120b" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_IncomeTaxReconciliationStateAndLocalIncomeTaxes" xlink:label="loc_us-gaap_IncomeTaxReconciliationStateAndLocalIncomeTaxes_bdbdc685-443d-bab4-6ccc-ce6a14aaa242" xlink:type="locator" />
    <link:calculationArc order="2" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IncomeTaxExpenseBenefit_78b7d85e-8366-fe6d-cb1f-faac5a041b79" xlink:to="loc_us-gaap_IncomeTaxReconciliationStateAndLocalIncomeTaxes_bdbdc685-443d-bab4-6ccc-ce6a14aaa242" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_IncomeTaxReconciliationForeignIncomeTaxRateDifferential" xlink:label="loc_us-gaap_IncomeTaxReconciliationForeignIncomeTaxRateDifferential_6f58335b-7001-079c-017e-8c9f80193d1b" xlink:type="locator" />
    <link:calculationArc order="3" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IncomeTaxExpenseBenefit_78b7d85e-8366-fe6d-cb1f-faac5a041b79" xlink:to="loc_us-gaap_IncomeTaxReconciliationForeignIncomeTaxRateDifferential_6f58335b-7001-079c-017e-8c9f80193d1b" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_IncomeTaxReconciliationChangeInDeferredTaxAssetsValuationAllowance" xlink:label="loc_us-gaap_IncomeTaxReconciliationChangeInDeferredTaxAssetsValuationAllowance_5a4be234-601b-ead6-df60-5106285cb5b9" xlink:type="locator" />
    <link:calculationArc order="4" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IncomeTaxExpenseBenefit_78b7d85e-8366-fe6d-cb1f-faac5a041b79" xlink:to="loc_us-gaap_IncomeTaxReconciliationChangeInDeferredTaxAssetsValuationAllowance_5a4be234-601b-ead6-df60-5106285cb5b9" xlink:type="arc" />
    <link:loc xlink:href="clh-20171231.xsd#clh_UncertainTaxPositionInterestAndPenaltiesNetOfBenefit" xlink:label="loc_clh_UncertainTaxPositionInterestAndPenaltiesNetOfBenefit_4b4150b7-085f-1ff1-5784-32a6ceac3839" xlink:type="locator" />
    <link:calculationArc order="5" weight="-1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IncomeTaxExpenseBenefit_78b7d85e-8366-fe6d-cb1f-faac5a041b79" xlink:to="loc_clh_UncertainTaxPositionInterestAndPenaltiesNetOfBenefit_4b4150b7-085f-1ff1-5784-32a6ceac3839" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_IncomeTaxReconciliationNondeductibleExpenseImpairmentLosses" xlink:label="loc_us-gaap_IncomeTaxReconciliationNondeductibleExpenseImpairmentLosses_11f79103-67b8-dc2f-717f-6b507fe84539" xlink:type="locator" />
    <link:calculationArc order="6" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IncomeTaxExpenseBenefit_78b7d85e-8366-fe6d-cb1f-faac5a041b79" xlink:to="loc_us-gaap_IncomeTaxReconciliationNondeductibleExpenseImpairmentLosses_11f79103-67b8-dc2f-717f-6b507fe84539" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_IncomeTaxReconciliationOtherAdjustments" xlink:label="loc_us-gaap_IncomeTaxReconciliationOtherAdjustments_0b1d9c48-50e9-fd05-543d-8637e0170a2a" xlink:type="locator" />
    <link:calculationArc order="7" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IncomeTaxExpenseBenefit_78b7d85e-8366-fe6d-cb1f-faac5a041b79" xlink:to="loc_us-gaap_IncomeTaxReconciliationOtherAdjustments_0b1d9c48-50e9-fd05-543d-8637e0170a2a" xlink:type="arc" />
    <link:loc xlink:href="clh-20171231.xsd#clh_EffectiveIncomeTaxRateReconciliationTaxCutsandJobsActof2017Amount" xlink:label="loc_clh_EffectiveIncomeTaxRateReconciliationTaxCutsandJobsActof2017Amount_9B2763094D4388CEEEDAB5E1DCE5C82D" xlink:type="locator" />
    <link:calculationArc order="8" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IncomeTaxExpenseBenefit_78b7d85e-8366-fe6d-cb1f-faac5a041b79" xlink:to="loc_clh_EffectiveIncomeTaxRateReconciliationTaxCutsandJobsActof2017Amount_9B2763094D4388CEEEDAB5E1DCE5C82D" xlink:type="arc" />
  </link:calculationLink>
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/IncomeTaxesProvisionForTaxExpenseDetailsCalc2" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_IncomeTaxExpenseBenefit" xlink:label="loc_us-gaap_IncomeTaxExpenseBenefit_36E8378BAEA259FAD3FDB5D548994A65_78b7d85e-8366-fe6d-cb1f-faac5a041b79" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_CurrentIncomeTaxExpenseBenefit" xlink:label="loc_us-gaap_CurrentIncomeTaxExpenseBenefit_36E8378BAEA259FAD3FDB5D548994A65_d2250640-c0ab-3b70-41b7-136d9a4aad78" xlink:type="locator" />
    <link:calculationArc order="1" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IncomeTaxExpenseBenefit_36E8378BAEA259FAD3FDB5D548994A65_78b7d85e-8366-fe6d-cb1f-faac5a041b79" xlink:to="loc_us-gaap_CurrentIncomeTaxExpenseBenefit_36E8378BAEA259FAD3FDB5D548994A65_d2250640-c0ab-3b70-41b7-136d9a4aad78" xlink:type="arc" />
    <link:loc xlink:href="clh-20171231.xsd#clh_DeferredIncomeTaxExpenseBenefitNetOfDiscontinuedOperations" xlink:label="loc_clh_DeferredIncomeTaxExpenseBenefitNetOfDiscontinuedOperations_36E8378BAEA259FAD3FDB5D548994A65_32ed1d6b-3788-96f2-e692-32a6cede5676" xlink:type="locator" />
    <link:calculationArc order="2" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IncomeTaxExpenseBenefit_36E8378BAEA259FAD3FDB5D548994A65_78b7d85e-8366-fe6d-cb1f-faac5a041b79" xlink:to="loc_clh_DeferredIncomeTaxExpenseBenefitNetOfDiscontinuedOperations_36E8378BAEA259FAD3FDB5D548994A65_32ed1d6b-3788-96f2-e692-32a6cede5676" xlink:type="arc" />
  </link:calculationLink>
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/IncomeTaxesTables" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/IncomeTaxesUnrecognizedTaxBenefitsDetails" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/InventoriesAndSupplies" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/InventoriesAndSuppliesDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_Supplies" xlink:label="loc_us-gaap_Supplies_d6f4772c-e6e5-f7ea-9ac8-7139c6506826" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_InventoryCrudeOilProductsAndMerchandise" xlink:label="loc_us-gaap_InventoryCrudeOilProductsAndMerchandise_8d2c298a-5bc6-98d5-693e-2164761bd046" xlink:type="locator" />
    <link:calculationArc order="1" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Supplies_d6f4772c-e6e5-f7ea-9ac8-7139c6506826" xlink:to="loc_us-gaap_InventoryCrudeOilProductsAndMerchandise_8d2c298a-5bc6-98d5-693e-2164761bd046" xlink:type="arc" />
    <link:loc xlink:href="clh-20171231.xsd#clh_EnergyRelatedInventorySuppliesAndDrums" xlink:label="loc_clh_EnergyRelatedInventorySuppliesAndDrums_e2bccfa6-d8ee-5e01-9453-cb24d9094953" xlink:type="locator" />
    <link:calculationArc order="2" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Supplies_d6f4772c-e6e5-f7ea-9ac8-7139c6506826" xlink:to="loc_clh_EnergyRelatedInventorySuppliesAndDrums_e2bccfa6-d8ee-5e01-9453-cb24d9094953" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_EnergyRelatedInventoryChemicals" xlink:label="loc_us-gaap_EnergyRelatedInventoryChemicals_f0125f5b-ecd5-156e-b357-9d540be046a3" xlink:type="locator" />
    <link:calculationArc order="3" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Supplies_d6f4772c-e6e5-f7ea-9ac8-7139c6506826" xlink:to="loc_us-gaap_EnergyRelatedInventoryChemicals_f0125f5b-ecd5-156e-b357-9d540be046a3" xlink:type="arc" />
    <link:loc xlink:href="clh-20171231.xsd#clh_EnergyRelatedInventoryOther" xlink:label="loc_clh_EnergyRelatedInventoryOther_86c355fa-cee7-bc2d-6cd4-cb24d913c28e" xlink:type="locator" />
    <link:calculationArc order="4" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Supplies_d6f4772c-e6e5-f7ea-9ac8-7139c6506826" xlink:to="loc_clh_EnergyRelatedInventoryOther_86c355fa-cee7-bc2d-6cd4-cb24d913c28e" xlink:type="arc" />
    <link:loc xlink:href="clh-20171231.xsd#clh_EnergyRelatedInventoryModularCampAccommodations" xlink:label="loc_clh_EnergyRelatedInventoryModularCampAccommodations_067c0cdf-8d74-139f-923c-cb24d8552108" xlink:type="locator" />
    <link:calculationArc order="5" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Supplies_d6f4772c-e6e5-f7ea-9ac8-7139c6506826" xlink:to="loc_clh_EnergyRelatedInventoryModularCampAccommodations_067c0cdf-8d74-139f-923c-cb24d8552108" xlink:type="arc" />
  </link:calculationLink>
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/InventoriesAndSuppliesTables" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/Operations" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/PropertyPlantAndEquipment" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/PropertyPlantAndEquipmentDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_PropertyPlantAndEquipmentNet" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentNet_1944a381-5c4e-ce3c-9111-13ccd1c639db" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_PropertyPlantAndEquipmentGross" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentGross_fe5a8e8b-5934-3dc5-9dae-7d40983185cf" xlink:type="locator" />
    <link:calculationArc order="1" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentNet_1944a381-5c4e-ce3c-9111-13ccd1c639db" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentGross_fe5a8e8b-5934-3dc5-9dae-7d40983185cf" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment" xlink:label="loc_us-gaap_AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment_5551841b-83e0-4644-fca8-d4027d932c0a" xlink:type="locator" />
    <link:calculationArc order="2" weight="-1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentNet_1944a381-5c4e-ce3c-9111-13ccd1c639db" xlink:to="loc_us-gaap_AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment_5551841b-83e0-4644-fca8-d4027d932c0a" xlink:type="arc" />
  </link:calculationLink>
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/PropertyPlantAndEquipmentTables" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/QuarterlyDataUnaudited" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/QuarterlyDataUnauditedDetails" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/QuarterlyDataUnauditedTables" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/RemedialLiabilities" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/RemedialLiabilitiesAdditionalInformationDetails" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/RemedialLiabilitiesAnticipatedPaymentsDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_AccrualForEnvironmentalLossContingencies" xlink:label="loc_us-gaap_AccrualForEnvironmentalLossContingencies_c8fb1c70-276e-7f30-efc4-b97b101f5293" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_AccrualForEnvironmentalLossContingenciesGross" xlink:label="loc_us-gaap_AccrualForEnvironmentalLossContingenciesGross_68c87f31-7cdb-c5cf-f3aa-4dc6f2bba021" xlink:type="locator" />
    <link:calculationArc order="1" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AccrualForEnvironmentalLossContingencies_c8fb1c70-276e-7f30-efc4-b97b101f5293" xlink:to="loc_us-gaap_AccrualForEnvironmentalLossContingenciesGross_68c87f31-7cdb-c5cf-f3aa-4dc6f2bba021" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_AccrualForEnvironmentalLossContingenciesUndiscountedDueWithinOneYear" xlink:label="loc_us-gaap_AccrualForEnvironmentalLossContingenciesUndiscountedDueWithinOneYear_c88a16f4-92da-3de8-a7c3-1d59a17881a9" xlink:type="locator" />
    <link:calculationArc order="1" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AccrualForEnvironmentalLossContingenciesGross_68c87f31-7cdb-c5cf-f3aa-4dc6f2bba021" xlink:to="loc_us-gaap_AccrualForEnvironmentalLossContingenciesUndiscountedDueWithinOneYear_c88a16f4-92da-3de8-a7c3-1d59a17881a9" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_AccrualForEnvironmentalLossContingenciesUndiscountedDueInSecondYear" xlink:label="loc_us-gaap_AccrualForEnvironmentalLossContingenciesUndiscountedDueInSecondYear_01e5364d-e661-177a-34e7-48c0cd284c91" xlink:type="locator" />
    <link:calculationArc order="2" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AccrualForEnvironmentalLossContingenciesGross_68c87f31-7cdb-c5cf-f3aa-4dc6f2bba021" xlink:to="loc_us-gaap_AccrualForEnvironmentalLossContingenciesUndiscountedDueInSecondYear_01e5364d-e661-177a-34e7-48c0cd284c91" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_AccrualForEnvironmentalLossContingenciesUndiscountedDueInThirdYear" xlink:label="loc_us-gaap_AccrualForEnvironmentalLossContingenciesUndiscountedDueInThirdYear_5d4781f7-197d-4b67-ac71-f91eb9f3f094" xlink:type="locator" />
    <link:calculationArc order="3" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AccrualForEnvironmentalLossContingenciesGross_68c87f31-7cdb-c5cf-f3aa-4dc6f2bba021" xlink:to="loc_us-gaap_AccrualForEnvironmentalLossContingenciesUndiscountedDueInThirdYear_5d4781f7-197d-4b67-ac71-f91eb9f3f094" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_AccrualForEnvironmentalLossContingenciesUndiscountedDueInFourthYear" xlink:label="loc_us-gaap_AccrualForEnvironmentalLossContingenciesUndiscountedDueInFourthYear_5720cedb-3f75-7c7f-7856-609daa408ebd" xlink:type="locator" />
    <link:calculationArc order="4" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AccrualForEnvironmentalLossContingenciesGross_68c87f31-7cdb-c5cf-f3aa-4dc6f2bba021" xlink:to="loc_us-gaap_AccrualForEnvironmentalLossContingenciesUndiscountedDueInFourthYear_5720cedb-3f75-7c7f-7856-609daa408ebd" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_AccrualForEnvironmentalLossContingenciesUndiscountedDueInFifthYear" xlink:label="loc_us-gaap_AccrualForEnvironmentalLossContingenciesUndiscountedDueInFifthYear_bb48e36f-3c7a-9be7-1af9-626a64b63792" xlink:type="locator" />
    <link:calculationArc order="5" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AccrualForEnvironmentalLossContingenciesGross_68c87f31-7cdb-c5cf-f3aa-4dc6f2bba021" xlink:to="loc_us-gaap_AccrualForEnvironmentalLossContingenciesUndiscountedDueInFifthYear_bb48e36f-3c7a-9be7-1af9-626a64b63792" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_AccrualForEnvironmentalLossContingenciesUndiscountedDueAfterFifthYear" xlink:label="loc_us-gaap_AccrualForEnvironmentalLossContingenciesUndiscountedDueAfterFifthYear_9393e2c7-d18e-e4f7-9712-a99ff2b0c126" xlink:type="locator" />
    <link:calculationArc order="6" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AccrualForEnvironmentalLossContingenciesGross_68c87f31-7cdb-c5cf-f3aa-4dc6f2bba021" xlink:to="loc_us-gaap_AccrualForEnvironmentalLossContingenciesUndiscountedDueAfterFifthYear_9393e2c7-d18e-e4f7-9712-a99ff2b0c126" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_AccrualForEnvironmentalLossContingenciesDiscount" xlink:label="loc_us-gaap_AccrualForEnvironmentalLossContingenciesDiscount_155491c6-769f-209e-a271-38ae3de4ce50" xlink:type="locator" />
    <link:calculationArc order="2" weight="-1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AccrualForEnvironmentalLossContingencies_c8fb1c70-276e-7f30-efc4-b97b101f5293" xlink:to="loc_us-gaap_AccrualForEnvironmentalLossContingenciesDiscount_155491c6-769f-209e-a271-38ae3de4ce50" xlink:type="arc" />
  </link:calculationLink>
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/RemedialLiabilitiesChangesInRemedialLiabilitiesDetails" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/RemedialLiabilitiesEstimatesDetails" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/RemedialLiabilitiesTables" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/ScheduleIiValuationAndQualifyingAccounts" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/ScheduleIiValuationAndQualifyingAccountsDetails" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/SegmentReporting" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/SegmentReportingSegmentAdditionalInformationDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_IntangibleAssetsNetIncludingGoodwill" xlink:label="loc_us-gaap_IntangibleAssetsNetIncludingGoodwill_c04dd71c-529e-62f9-136d-a0a478e6fbc1" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_Goodwill" xlink:label="loc_us-gaap_Goodwill_93a64cae-271a-5e6b-8c83-5adf9f941142" xlink:type="locator" />
    <link:calculationArc order="1" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IntangibleAssetsNetIncludingGoodwill_c04dd71c-529e-62f9-136d-a0a478e6fbc1" xlink:to="loc_us-gaap_Goodwill_93a64cae-271a-5e6b-8c83-5adf9f941142" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_IntangibleAssetsNetExcludingGoodwill" xlink:label="loc_us-gaap_IntangibleAssetsNetExcludingGoodwill_1fe06082-076b-052d-6e2e-930afe9d6b2d" xlink:type="locator" />
    <link:calculationArc order="2" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IntangibleAssetsNetIncludingGoodwill_c04dd71c-529e-62f9-136d-a0a478e6fbc1" xlink:to="loc_us-gaap_IntangibleAssetsNetExcludingGoodwill_1fe06082-076b-052d-6e2e-930afe9d6b2d" xlink:type="arc" />
  </link:calculationLink>
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/SegmentReportingSegmentInformationRevenuesEbitaAndReconciliationToConsolidatedStatementOfOperationsDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_OperatingIncomeLoss" xlink:label="loc_us-gaap_OperatingIncomeLoss_9894e895-7695-402a-9f03-08d60b7373b8" xlink:type="locator" />
    <link:loc xlink:href="clh-20171231.xsd#clh_AccretionOfEnvironmentalLiabilities" xlink:label="loc_clh_AccretionOfEnvironmentalLiabilities_b2493bcd-b4b5-8fe0-cc7a-cb24d8f78231" xlink:type="locator" />
    <link:calculationArc order="1" weight="-1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OperatingIncomeLoss_9894e895-7695-402a-9f03-08d60b7373b8" xlink:to="loc_clh_AccretionOfEnvironmentalLiabilities_b2493bcd-b4b5-8fe0-cc7a-cb24d8f78231" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DepreciationDepletionAndAmortization" xlink:label="loc_us-gaap_DepreciationDepletionAndAmortization_37b0c31d-5d8b-0577-dfd9-aa56a79334e3" xlink:type="locator" />
    <link:calculationArc order="2" weight="-1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OperatingIncomeLoss_9894e895-7695-402a-9f03-08d60b7373b8" xlink:to="loc_us-gaap_DepreciationDepletionAndAmortization_37b0c31d-5d8b-0577-dfd9-aa56a79334e3" xlink:type="arc" />
    <link:loc xlink:href="clh-20171231.xsd#clh_IncomeLossFromContinuingOperationsBeforeInterestTaxDepreciationAndAmortizationNet" xlink:label="loc_clh_IncomeLossFromContinuingOperationsBeforeInterestTaxDepreciationAndAmortizationNet_03f662ee-e6de-36b6-4015-cb24d8fc3dca" xlink:type="locator" />
    <link:calculationArc order="3" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OperatingIncomeLoss_9894e895-7695-402a-9f03-08d60b7373b8" xlink:to="loc_clh_IncomeLossFromContinuingOperationsBeforeInterestTaxDepreciationAndAmortizationNet_03f662ee-e6de-36b6-4015-cb24d8fc3dca" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_GoodwillImpairmentLoss" xlink:label="loc_us-gaap_GoodwillImpairmentLoss_fca284fd-6d29-9ad5-2fe0-048c9053b712" xlink:type="locator" />
    <link:calculationArc order="4" weight="-1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OperatingIncomeLoss_9894e895-7695-402a-9f03-08d60b7373b8" xlink:to="loc_us-gaap_GoodwillImpairmentLoss_fca284fd-6d29-9ad5-2fe0-048c9053b712" xlink:type="arc" />
  </link:calculationLink>
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/SegmentReportingTables" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/SignificantAccountingPolicies" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/SignificantAccountingPoliciesAdvertisingExpenseDetails" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/SignificantAccountingPoliciesAvailableForSaleInvestmentsDetails" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/SignificantAccountingPoliciesCashCashEquivalentsAndUncashedChecksDetails" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/SignificantAccountingPoliciesCreditConcentrationDetails" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/SignificantAccountingPoliciesFinancialAssetsMeasuredOnRecurringBasisDetails" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/SignificantAccountingPoliciesGoodwillAndIntangibleAssetsDetails" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/SignificantAccountingPoliciesLandfillAccountingDetails" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/SignificantAccountingPoliciesMarketableSecuritiesByContractualMaturityDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_AvailableForSaleSecuritiesDebtSecurities" xlink:label="loc_us-gaap_AvailableForSaleSecuritiesDebtSecurities_2c867d9b-5594-18ef-c82a-679b606d1bd3" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_AvailableForSaleSecuritiesDebtMaturitiesWithinOneYearFairValue" xlink:label="loc_us-gaap_AvailableForSaleSecuritiesDebtMaturitiesWithinOneYearFairValue_4836856d-11b6-313b-8616-6a2c8b77e26f" xlink:type="locator" />
    <link:calculationArc order="1" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AvailableForSaleSecuritiesDebtSecurities_2c867d9b-5594-18ef-c82a-679b606d1bd3" xlink:to="loc_us-gaap_AvailableForSaleSecuritiesDebtMaturitiesWithinOneYearFairValue_4836856d-11b6-313b-8616-6a2c8b77e26f" xlink:type="arc" />
    <link:loc xlink:href="clh-20171231.xsd#clh_AvailableforsaleSecuritiesDebtMaturitiesYearTwoThroughThreeFairValue" xlink:label="loc_clh_AvailableforsaleSecuritiesDebtMaturitiesYearTwoThroughThreeFairValue_7B1039C6E24B63824D1272340CA9ACE6" xlink:type="locator" />
    <link:calculationArc order="2" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AvailableForSaleSecuritiesDebtSecurities_2c867d9b-5594-18ef-c82a-679b606d1bd3" xlink:to="loc_clh_AvailableforsaleSecuritiesDebtMaturitiesYearTwoThroughThreeFairValue_7B1039C6E24B63824D1272340CA9ACE6" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_AvailableForSaleDebtSecuritiesAmortizedCostBasis" xlink:label="loc_us-gaap_AvailableForSaleDebtSecuritiesAmortizedCostBasis_fc961581-2899-aa00-cc82-b67bd4267bb3" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_AvailableForSaleSecuritiesDebtMaturitiesWithinOneYearAmortizedCost" xlink:label="loc_us-gaap_AvailableForSaleSecuritiesDebtMaturitiesWithinOneYearAmortizedCost_065ac417-143a-3361-82a5-1e59ffd9749a" xlink:type="locator" />
    <link:calculationArc order="1" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AvailableForSaleDebtSecuritiesAmortizedCostBasis_fc961581-2899-aa00-cc82-b67bd4267bb3" xlink:to="loc_us-gaap_AvailableForSaleSecuritiesDebtMaturitiesWithinOneYearAmortizedCost_065ac417-143a-3361-82a5-1e59ffd9749a" xlink:type="arc" />
    <link:loc xlink:href="clh-20171231.xsd#clh_AvailableforsaleSecuritiesDebtMaturitiesYearTwoThroughThreeAmortizedCostBasis" xlink:label="loc_clh_AvailableforsaleSecuritiesDebtMaturitiesYearTwoThroughThreeAmortizedCostBasis_635887AD12D6525A182E72337331E3BA" xlink:type="locator" />
    <link:calculationArc order="2" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AvailableForSaleDebtSecuritiesAmortizedCostBasis_fc961581-2899-aa00-cc82-b67bd4267bb3" xlink:to="loc_clh_AvailableforsaleSecuritiesDebtMaturitiesYearTwoThroughThreeAmortizedCostBasis_635887AD12D6525A182E72337331E3BA" xlink:type="arc" />
  </link:calculationLink>
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/SignificantAccountingPoliciesPolicies" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/SignificantAccountingPoliciesPropertyPlantAndEquipmentDetails" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/SignificantAccountingPoliciesRecentlyAccountingPronouncementsDetails" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/SignificantAccountingPoliciesRemedialLiabilitiesDetails" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/SignificantAccountingPoliciesRevenueRecognitionAndDeferredRevenueDetails" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/SignificantAccountingPoliciesTables" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/StockBasedCompensationAndEmployeeBenefitPlans" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/StockBasedCompensationAndEmployeeBenefitPlansEmployeeBenefitPlansDetails" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/StockBasedCompensationAndEmployeeBenefitPlansPerformanceStockAwardsDetails" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/StockBasedCompensationAndEmployeeBenefitPlansRestrictedStockAwardsDetails" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/StockBasedCompensationAndEmployeeBenefitPlansStockBasedCompensationDetails" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/StockBasedCompensationAndEmployeeBenefitPlansTables" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/StockholdersEquity" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/StockholdersEquityDetails" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/SubsequentEvents" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/SubsequentEventsSubsequentEventsDetails" xlink:type="extended" />
</link:linkbase>