<?xml version="1.0" encoding="UTF-8"?>

<!--XBRL Document Created with Wdesk from Workiva-->
<!--Copyright 2020 Workiva-->
<!--r:a4bafda7-83bc-4b3c-b6fc-4d91f84cc6d2,g:24c95c19-c160-4a76-bb9b-bc8003ee9f83-->
<link:linkbase xmlns:link="http://www.xbrl.org/2003/linkbase" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.xbrl.org/2003/linkbase http://www.xbrl.org/2003/xbrl-linkbase-2003-12-31.xsd">
  <link:roleRef roleURI="http://www.cleanharbors.com/role/Cover" xlink:type="simple" xlink:href="clh-20200930.xsd#Cover"/>
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/Cover" xlink:type="extended"/>
  <link:roleRef roleURI="http://www.cleanharbors.com/role/CONSOLIDATEDBALANCESHEETS" xlink:type="simple" xlink:href="clh-20200930.xsd#CONSOLIDATEDBALANCESHEETS"/>
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/CONSOLIDATEDBALANCESHEETS" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockholdersEquity_4b75336e-42c8-4357-bb31-75318b3db806" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StockholdersEquity"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockValue_d199969b-9e9f-4994-ba46-4c81be3173ae" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CommonStockValue"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_StockholdersEquity_4b75336e-42c8-4357-bb31-75318b3db806" xlink:to="loc_us-gaap_CommonStockValue_d199969b-9e9f-4994-ba46-4c81be3173ae" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AdditionalPaidInCapitalCommonStock_cd074733-2550-4998-bf32-f3edbee8e861" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AdditionalPaidInCapitalCommonStock"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_StockholdersEquity_4b75336e-42c8-4357-bb31-75318b3db806" xlink:to="loc_us-gaap_AdditionalPaidInCapitalCommonStock_cd074733-2550-4998-bf32-f3edbee8e861" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax_16927c31-8306-4586-a5af-f7a58396e147" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_StockholdersEquity_4b75336e-42c8-4357-bb31-75318b3db806" xlink:to="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax_16927c31-8306-4586-a5af-f7a58396e147" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RetainedEarningsAccumulatedDeficit_6607e370-703c-4ab5-98cc-cc03c6863181" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RetainedEarningsAccumulatedDeficit"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_StockholdersEquity_4b75336e-42c8-4357-bb31-75318b3db806" xlink:to="loc_us-gaap_RetainedEarningsAccumulatedDeficit_6607e370-703c-4ab5-98cc-cc03c6863181" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_Assets_86d1168a-c8f7-4c21-9b08-e0f64ec318d2" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_Assets"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AssetsCurrent_50d3145b-2b32-4844-bbbe-1445fb410eec" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AssetsCurrent"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Assets_86d1168a-c8f7-4c21-9b08-e0f64ec318d2" xlink:to="loc_us-gaap_AssetsCurrent_50d3145b-2b32-4844-bbbe-1445fb410eec" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_clh_AssetsNoncurrentExcludingPropertyPlantAndEquipment_8dcd0f60-573f-4c66-8dad-c8b1872dce2f" xlink:href="clh-20200930.xsd#clh_AssetsNoncurrentExcludingPropertyPlantAndEquipment"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Assets_86d1168a-c8f7-4c21-9b08-e0f64ec318d2" xlink:to="loc_clh_AssetsNoncurrentExcludingPropertyPlantAndEquipment_8dcd0f60-573f-4c66-8dad-c8b1872dce2f" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentAndFinanceLeaseRightOfUseAssetAfterAccumulatedDepreciationAndAmortization_b5761482-e213-4fec-8ac6-be8c5ecb4e36" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PropertyPlantAndEquipmentAndFinanceLeaseRightOfUseAssetAfterAccumulatedDepreciationAndAmortization"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Assets_86d1168a-c8f7-4c21-9b08-e0f64ec318d2" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentAndFinanceLeaseRightOfUseAssetAfterAccumulatedDepreciationAndAmortization_b5761482-e213-4fec-8ac6-be8c5ecb4e36" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LiabilitiesAndStockholdersEquity_5d75f6b5-6205-4368-bbf4-25b7b2fd26d9" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LiabilitiesAndStockholdersEquity"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockholdersEquity_a2e56021-35e8-49a7-8f0d-ee13d5269499" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StockholdersEquity"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquity_5d75f6b5-6205-4368-bbf4-25b7b2fd26d9" xlink:to="loc_us-gaap_StockholdersEquity_a2e56021-35e8-49a7-8f0d-ee13d5269499" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LiabilitiesNoncurrent_1d322bc4-6014-422f-9998-c299ba420ea9" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LiabilitiesNoncurrent"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquity_5d75f6b5-6205-4368-bbf4-25b7b2fd26d9" xlink:to="loc_us-gaap_LiabilitiesNoncurrent_1d322bc4-6014-422f-9998-c299ba420ea9" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LiabilitiesCurrent_74bc3f74-592d-493e-aaac-5a4682cd5174" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LiabilitiesCurrent"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquity_5d75f6b5-6205-4368-bbf4-25b7b2fd26d9" xlink:to="loc_us-gaap_LiabilitiesCurrent_74bc3f74-592d-493e-aaac-5a4682cd5174" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommitmentsAndContingencies_ffb3c75b-7570-4fb6-a494-3d56ccd1df06" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CommitmentsAndContingencies"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquity_5d75f6b5-6205-4368-bbf4-25b7b2fd26d9" xlink:to="loc_us-gaap_CommitmentsAndContingencies_ffb3c75b-7570-4fb6-a494-3d56ccd1df06" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_clh_AssetsNoncurrentExcludingPropertyPlantAndEquipment_7fa5dea5-ead2-4328-8436-d7f5f5724924" xlink:href="clh-20200930.xsd#clh_AssetsNoncurrentExcludingPropertyPlantAndEquipment"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingLeaseRightOfUseAsset_1dc291f7-20e4-4778-8d99-82d3a5d18b96" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OperatingLeaseRightOfUseAsset"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_clh_AssetsNoncurrentExcludingPropertyPlantAndEquipment_7fa5dea5-ead2-4328-8436-d7f5f5724924" xlink:to="loc_us-gaap_OperatingLeaseRightOfUseAsset_1dc291f7-20e4-4778-8d99-82d3a5d18b96" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_Goodwill_359c23e6-f41b-4ade-bfb4-f042e82780e3" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_Goodwill"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_clh_AssetsNoncurrentExcludingPropertyPlantAndEquipment_7fa5dea5-ead2-4328-8436-d7f5f5724924" xlink:to="loc_us-gaap_Goodwill_359c23e6-f41b-4ade-bfb4-f042e82780e3" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IntangibleAssetsNetExcludingGoodwill_168f520d-7ee2-4e68-a3d7-ada162bba8d1" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IntangibleAssetsNetExcludingGoodwill"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_clh_AssetsNoncurrentExcludingPropertyPlantAndEquipment_7fa5dea5-ead2-4328-8436-d7f5f5724924" xlink:to="loc_us-gaap_IntangibleAssetsNetExcludingGoodwill_168f520d-7ee2-4e68-a3d7-ada162bba8d1" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherAssetsNoncurrent_5bc02baa-6434-4197-af1e-9c2867782fbe" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherAssetsNoncurrent"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_clh_AssetsNoncurrentExcludingPropertyPlantAndEquipment_7fa5dea5-ead2-4328-8436-d7f5f5724924" xlink:to="loc_us-gaap_OtherAssetsNoncurrent_5bc02baa-6434-4197-af1e-9c2867782fbe" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LiabilitiesNoncurrent_d7dd39ec-a47f-46d7-bea8-48061a3d653b" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LiabilitiesNoncurrent"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongTermDebtNoncurrent_0072de94-0628-44ae-8412-2d2d41a9ce14" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LongTermDebtNoncurrent"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesNoncurrent_d7dd39ec-a47f-46d7-bea8-48061a3d653b" xlink:to="loc_us-gaap_LongTermDebtNoncurrent_0072de94-0628-44ae-8412-2d2d41a9ce14" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_clh_UnrecognizedTaxBenefitsAndOtherLongTermLiabilitiesNoncurrent_c8abd8f1-bb75-43d3-bb5a-d7e62d14623a" xlink:href="clh-20200930.xsd#clh_UnrecognizedTaxBenefitsAndOtherLongTermLiabilitiesNoncurrent"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesNoncurrent_d7dd39ec-a47f-46d7-bea8-48061a3d653b" xlink:to="loc_clh_UnrecognizedTaxBenefitsAndOtherLongTermLiabilitiesNoncurrent_c8abd8f1-bb75-43d3-bb5a-d7e62d14623a" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccruedEnvironmentalLossContingenciesNoncurrent_7e96f150-c0d6-4e64-92d0-2151bd0e0e07" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AccruedEnvironmentalLossContingenciesNoncurrent"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesNoncurrent_d7dd39ec-a47f-46d7-bea8-48061a3d653b" xlink:to="loc_us-gaap_AccruedEnvironmentalLossContingenciesNoncurrent_7e96f150-c0d6-4e64-92d0-2151bd0e0e07" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccruedCappingClosurePostClosureAndEnvironmentalCostsNoncurrent_932a76e2-dfc2-4160-8b0a-52bc2d18fa8d" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AccruedCappingClosurePostClosureAndEnvironmentalCostsNoncurrent"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesNoncurrent_d7dd39ec-a47f-46d7-bea8-48061a3d653b" xlink:to="loc_us-gaap_AccruedCappingClosurePostClosureAndEnvironmentalCostsNoncurrent_932a76e2-dfc2-4160-8b0a-52bc2d18fa8d" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingLeaseLiabilityNoncurrent_d3fc5c01-8961-4c00-be2d-73147967f25c" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OperatingLeaseLiabilityNoncurrent"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesNoncurrent_d7dd39ec-a47f-46d7-bea8-48061a3d653b" xlink:to="loc_us-gaap_OperatingLeaseLiabilityNoncurrent_d3fc5c01-8961-4c00-be2d-73147967f25c" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LiabilitiesCurrent_7b8814a7-e995-44c0-8b11-a479c07e2986" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LiabilitiesCurrent"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongTermDebtCurrent_7ad56674-b780-4a53-84d3-998b88daa1eb" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LongTermDebtCurrent"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesCurrent_7b8814a7-e995-44c0-8b11-a479c07e2986" xlink:to="loc_us-gaap_LongTermDebtCurrent_7ad56674-b780-4a53-84d3-998b88daa1eb" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountsPayableCurrent_997d5c81-9b0e-4ff6-aca0-c5b745587e00" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AccountsPayableCurrent"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesCurrent_7b8814a7-e995-44c0-8b11-a479c07e2986" xlink:to="loc_us-gaap_AccountsPayableCurrent_997d5c81-9b0e-4ff6-aca0-c5b745587e00" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccruedLiabilitiesCurrent_2e2549db-b886-43a2-8c70-25bee330340a" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AccruedLiabilitiesCurrent"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesCurrent_7b8814a7-e995-44c0-8b11-a479c07e2986" xlink:to="loc_us-gaap_AccruedLiabilitiesCurrent_2e2549db-b886-43a2-8c70-25bee330340a" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_clh_AccruedCappingClosurePostClosureAndRemedialLiabilitiesCurrent_fd7e3a36-a1f8-42da-a8d9-0dfd321e858b" xlink:href="clh-20200930.xsd#clh_AccruedCappingClosurePostClosureAndRemedialLiabilitiesCurrent"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesCurrent_7b8814a7-e995-44c0-8b11-a479c07e2986" xlink:to="loc_clh_AccruedCappingClosurePostClosureAndRemedialLiabilitiesCurrent_fd7e3a36-a1f8-42da-a8d9-0dfd321e858b" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ContractWithCustomerLiabilityCurrent_d821662d-6219-456d-ba97-18eff2d214f8" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ContractWithCustomerLiabilityCurrent"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesCurrent_7b8814a7-e995-44c0-8b11-a479c07e2986" xlink:to="loc_us-gaap_ContractWithCustomerLiabilityCurrent_d821662d-6219-456d-ba97-18eff2d214f8" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingLeaseLiabilityCurrent_55be7f2c-924b-4ca5-9e2c-f62cf8db6c80" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OperatingLeaseLiabilityCurrent"/>
    <link:calculationArc order="6" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesCurrent_7b8814a7-e995-44c0-8b11-a479c07e2986" xlink:to="loc_us-gaap_OperatingLeaseLiabilityCurrent_55be7f2c-924b-4ca5-9e2c-f62cf8db6c80" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AssetsCurrent_7577c2d7-e78b-4645-9913-8d026c504a8f" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AssetsCurrent"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountsReceivableNetCurrent_dddacdb8-62c9-41f9-aef4-fbb169c5b820" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AccountsReceivableNetCurrent"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AssetsCurrent_7577c2d7-e78b-4645-9913-8d026c504a8f" xlink:to="loc_us-gaap_AccountsReceivableNetCurrent_dddacdb8-62c9-41f9-aef4-fbb169c5b820" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_Supplies_0490a54a-8feb-49c0-9a06-bc6e6b5cf8b1" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_Supplies"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AssetsCurrent_7577c2d7-e78b-4645-9913-8d026c504a8f" xlink:to="loc_us-gaap_Supplies_0490a54a-8feb-49c0-9a06-bc6e6b5cf8b1" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredFinanceCostsCurrentNet_ef99712d-fe0e-4eb5-8471-8eb7b0eb0056" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DeferredFinanceCostsCurrentNet"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AssetsCurrent_7577c2d7-e78b-4645-9913-8d026c504a8f" xlink:to="loc_us-gaap_DeferredFinanceCostsCurrentNet_ef99712d-fe0e-4eb5-8471-8eb7b0eb0056" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_MarketableSecuritiesCurrent_a4205a7a-1c05-45ec-bc94-fd64c2f1a5b5" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_MarketableSecuritiesCurrent"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AssetsCurrent_7577c2d7-e78b-4645-9913-8d026c504a8f" xlink:to="loc_us-gaap_MarketableSecuritiesCurrent_a4205a7a-1c05-45ec-bc94-fd64c2f1a5b5" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashAndCashEquivalentsAtCarryingValue_038d7e51-6ac3-41ed-9b6a-efbd1f0cef68" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CashAndCashEquivalentsAtCarryingValue"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AssetsCurrent_7577c2d7-e78b-4645-9913-8d026c504a8f" xlink:to="loc_us-gaap_CashAndCashEquivalentsAtCarryingValue_038d7e51-6ac3-41ed-9b6a-efbd1f0cef68" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_clh_UnbilledAccountsReceivableCurrent_c410c03e-8e43-4cec-aa64-ec7625fdf37d" xlink:href="clh-20200930.xsd#clh_UnbilledAccountsReceivableCurrent"/>
    <link:calculationArc order="6" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AssetsCurrent_7577c2d7-e78b-4645-9913-8d026c504a8f" xlink:to="loc_clh_UnbilledAccountsReceivableCurrent_c410c03e-8e43-4cec-aa64-ec7625fdf37d" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PrepaidExpenseAndOtherAssetsCurrent_9faabfc3-aece-41e6-8129-ae7924611ffa" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PrepaidExpenseAndOtherAssetsCurrent"/>
    <link:calculationArc order="7" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AssetsCurrent_7577c2d7-e78b-4645-9913-8d026c504a8f" xlink:to="loc_us-gaap_PrepaidExpenseAndOtherAssetsCurrent_9faabfc3-aece-41e6-8129-ae7924611ffa" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.cleanharbors.com/role/CONSOLIDATEDBALANCESHEETSParenthetical" xlink:type="simple" xlink:href="clh-20200930.xsd#CONSOLIDATEDBALANCESHEETSParenthetical"/>
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/CONSOLIDATEDBALANCESHEETSParenthetical" xlink:type="extended"/>
  <link:roleRef roleURI="http://www.cleanharbors.com/role/UNAUDITEDCONSOLIDATEDSTATEMENTSOFOPERATIONS" xlink:type="simple" xlink:href="clh-20200930.xsd#UNAUDITEDCONSOLIDATEDSTATEMENTSOFOPERATIONS"/>
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/UNAUDITEDCONSOLIDATEDSTATEMENTSOFOPERATIONS" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingIncomeLoss_60b979cd-2fe0-4209-9806-a14aea615348" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OperatingIncomeLoss"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax_97a29297-45ed-4660-bb64-07b1bfc6979e" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OperatingIncomeLoss_60b979cd-2fe0-4209-9806-a14aea615348" xlink:to="loc_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax_97a29297-45ed-4660-bb64-07b1bfc6979e" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CostOfGoodsAndServicesSold_293a0366-7986-4135-af7c-11daf52718cf" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CostOfGoodsAndServicesSold"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OperatingIncomeLoss_60b979cd-2fe0-4209-9806-a14aea615348" xlink:to="loc_us-gaap_CostOfGoodsAndServicesSold_293a0366-7986-4135-af7c-11daf52718cf" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SellingGeneralAndAdministrativeExpense_ac91f4e6-0a61-4bc7-b05c-91d671fc82c5" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SellingGeneralAndAdministrativeExpense"/>
    <link:calculationArc order="3" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OperatingIncomeLoss_60b979cd-2fe0-4209-9806-a14aea615348" xlink:to="loc_us-gaap_SellingGeneralAndAdministrativeExpense_ac91f4e6-0a61-4bc7-b05c-91d671fc82c5" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_clh_AccretionOfEnvironmentalLiabilities_94f74d88-f3d7-4aff-948c-4fb909f3a46e" xlink:href="clh-20200930.xsd#clh_AccretionOfEnvironmentalLiabilities"/>
    <link:calculationArc order="4" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OperatingIncomeLoss_60b979cd-2fe0-4209-9806-a14aea615348" xlink:to="loc_clh_AccretionOfEnvironmentalLiabilities_94f74d88-f3d7-4aff-948c-4fb909f3a46e" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DepreciationDepletionAndAmortization_23ec2a22-a1a4-47f0-9854-785b0ff690ff" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DepreciationDepletionAndAmortization"/>
    <link:calculationArc order="5" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OperatingIncomeLoss_60b979cd-2fe0-4209-9806-a14aea615348" xlink:to="loc_us-gaap_DepreciationDepletionAndAmortization_23ec2a22-a1a4-47f0-9854-785b0ff690ff" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetIncomeLoss_526186c8-71ee-4d47-ad17-0e8eae1f4498" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NetIncomeLoss"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments_8577316e-2b97-45c5-b92a-cd42fda07fea" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetIncomeLoss_526186c8-71ee-4d47-ad17-0e8eae1f4498" xlink:to="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments_8577316e-2b97-45c5-b92a-cd42fda07fea" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeTaxExpenseBenefit_909bde60-d8aa-41dc-9cb2-481db9d0a1cc" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeTaxExpenseBenefit"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetIncomeLoss_526186c8-71ee-4d47-ad17-0e8eae1f4498" xlink:to="loc_us-gaap_IncomeTaxExpenseBenefit_909bde60-d8aa-41dc-9cb2-481db9d0a1cc" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments_00dc58db-5e9d-4d95-b6e6-d7f9c2497923" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingIncomeLoss_de6bfb11-db30-4c2f-8e59-e84d4afe11b7" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OperatingIncomeLoss"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments_00dc58db-5e9d-4d95-b6e6-d7f9c2497923" xlink:to="loc_us-gaap_OperatingIncomeLoss_de6bfb11-db30-4c2f-8e59-e84d4afe11b7" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherNonoperatingIncomeExpense_bcc9e662-352c-4eec-86cc-a339d5f6f312" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherNonoperatingIncomeExpense"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments_00dc58db-5e9d-4d95-b6e6-d7f9c2497923" xlink:to="loc_us-gaap_OtherNonoperatingIncomeExpense_bcc9e662-352c-4eec-86cc-a339d5f6f312" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_GainLossOnSaleOfBusiness_826c2d7d-0a9e-4deb-a055-1ec37919c175" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_GainLossOnSaleOfBusiness"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments_00dc58db-5e9d-4d95-b6e6-d7f9c2497923" xlink:to="loc_us-gaap_GainLossOnSaleOfBusiness_826c2d7d-0a9e-4deb-a055-1ec37919c175" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_GainsLossesOnExtinguishmentOfDebt_cec624de-6d58-455c-876c-1cb0ad812413" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_GainsLossesOnExtinguishmentOfDebt"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments_00dc58db-5e9d-4d95-b6e6-d7f9c2497923" xlink:to="loc_us-gaap_GainsLossesOnExtinguishmentOfDebt_cec624de-6d58-455c-876c-1cb0ad812413" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestIncomeExpenseNonoperatingNet_c8e19184-387e-4774-bdb9-fc786f83016f" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_InterestIncomeExpenseNonoperatingNet"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments_00dc58db-5e9d-4d95-b6e6-d7f9c2497923" xlink:to="loc_us-gaap_InterestIncomeExpenseNonoperatingNet_c8e19184-387e-4774-bdb9-fc786f83016f" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.cleanharbors.com/role/UNAUDITEDCONSOLIDATEDSTATEMENTSOFOPERATIONSParenthetical" xlink:type="simple" xlink:href="clh-20200930.xsd#UNAUDITEDCONSOLIDATEDSTATEMENTSOFOPERATIONSParenthetical"/>
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/UNAUDITEDCONSOLIDATEDSTATEMENTSOFOPERATIONSParenthetical" xlink:type="extended"/>
  <link:roleRef roleURI="http://www.cleanharbors.com/role/UNAUDITEDCONSOLIDATEDSTATEMENTSOFCOMPREHENSIVEINCOME" xlink:type="simple" xlink:href="clh-20200930.xsd#UNAUDITEDCONSOLIDATEDSTATEMENTSOFCOMPREHENSIVEINCOME"/>
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/UNAUDITEDCONSOLIDATEDSTATEMENTSOFCOMPREHENSIVEINCOME" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ComprehensiveIncomeNetOfTax_17e0e5ac-16b7-4502-8f3c-5ce874bdab40" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ComprehensiveIncomeNetOfTax"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetIncomeLoss_fef010f3-3dd0-44b7-ad24-a4321cd2f87d" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NetIncomeLoss"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_ComprehensiveIncomeNetOfTax_17e0e5ac-16b7-4502-8f3c-5ce874bdab40" xlink:to="loc_us-gaap_NetIncomeLoss_fef010f3-3dd0-44b7-ad24-a4321cd2f87d" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent_b0376f5c-38d8-4479-a15d-c86fba3f49ca" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_ComprehensiveIncomeNetOfTax_17e0e5ac-16b7-4502-8f3c-5ce874bdab40" xlink:to="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent_b0376f5c-38d8-4479-a15d-c86fba3f49ca" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent_9ba1ed82-05fe-489a-99b6-1ebd4dac27a1" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodNetOfTax_288aff16-f302-4430-b22b-bf0606cd5404" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodNetOfTax"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent_9ba1ed82-05fe-489a-99b6-1ebd4dac27a1" xlink:to="loc_us-gaap_OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodNetOfTax_288aff16-f302-4430-b22b-bf0606cd5404" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossCashFlowHedgeGainLossReclassificationAfterTax_c5be131a-0db5-4aee-923a-8bba62bdceb6" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossCashFlowHedgeGainLossReclassificationAfterTax"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent_9ba1ed82-05fe-489a-99b6-1ebd4dac27a1" xlink:to="loc_us-gaap_OtherComprehensiveIncomeLossCashFlowHedgeGainLossReclassificationAfterTax_c5be131a-0db5-4aee-923a-8bba62bdceb6" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationAdjustmentNetOfTaxPortionAttributableToParent_2e8167e0-bdcf-41d0-8350-7d1e49f0cf1a" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationAdjustmentNetOfTaxPortionAttributableToParent"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent_9ba1ed82-05fe-489a-99b6-1ebd4dac27a1" xlink:to="loc_us-gaap_OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationAdjustmentNetOfTaxPortionAttributableToParent_2e8167e0-bdcf-41d0-8350-7d1e49f0cf1a" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossCashFlowHedgeGainLossBeforeReclassificationAfterTax_a97f16ff-8456-4a0d-ad93-dee8a61cf9da" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossCashFlowHedgeGainLossBeforeReclassificationAfterTax"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent_9ba1ed82-05fe-489a-99b6-1ebd4dac27a1" xlink:to="loc_us-gaap_OtherComprehensiveIncomeLossCashFlowHedgeGainLossBeforeReclassificationAfterTax_a97f16ff-8456-4a0d-ad93-dee8a61cf9da" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossReclassificationAdjustmentFromAOCIForSaleOfSecuritiesNetOfTax_13435c92-a760-4f69-8463-dd90af292246" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossReclassificationAdjustmentFromAOCIForSaleOfSecuritiesNetOfTax"/>
    <link:calculationArc order="5" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent_9ba1ed82-05fe-489a-99b6-1ebd4dac27a1" xlink:to="loc_us-gaap_OtherComprehensiveIncomeLossReclassificationAdjustmentFromAOCIForSaleOfSecuritiesNetOfTax_13435c92-a760-4f69-8463-dd90af292246" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.cleanharbors.com/role/UNAUDITEDCONSOLIDATEDSTATEMENTSOFCASHFLOWS" xlink:type="simple" xlink:href="clh-20200930.xsd#UNAUDITEDCONSOLIDATEDSTATEMENTSOFCASHFLOWS"/>
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/UNAUDITEDCONSOLIDATEDSTATEMENTSOFCASHFLOWS" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_507531d2-f049-4b79-aca2-51dfcd41f3f2" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NetCashProvidedByUsedInFinancingActivities"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinanceLeasePrincipalPayments_609ab610-6a61-4a5b-81b5-a1df71a3b3ad" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FinanceLeasePrincipalPayments"/>
    <link:calculationArc order="1" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_507531d2-f049-4b79-aca2-51dfcd41f3f2" xlink:to="loc_us-gaap_FinanceLeasePrincipalPayments_609ab610-6a61-4a5b-81b5-a1df71a3b3ad" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsRelatedToTaxWithholdingForShareBasedCompensation_75c10b20-fe48-4969-8944-b20ad6bc7d6e" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PaymentsRelatedToTaxWithholdingForShareBasedCompensation"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_507531d2-f049-4b79-aca2-51dfcd41f3f2" xlink:to="loc_us-gaap_PaymentsRelatedToTaxWithholdingForShareBasedCompensation_75c10b20-fe48-4969-8944-b20ad6bc7d6e" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RepaymentsOfLinesOfCredit_870a4875-89ae-46c8-99a7-62337d96de9f" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RepaymentsOfLinesOfCredit"/>
    <link:calculationArc order="3" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_507531d2-f049-4b79-aca2-51dfcd41f3f2" xlink:to="loc_us-gaap_RepaymentsOfLinesOfCredit_870a4875-89ae-46c8-99a7-62337d96de9f" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromLinesOfCredit_29e71311-db23-4f1b-bb2c-7b61995fe411" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ProceedsFromLinesOfCredit"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_507531d2-f049-4b79-aca2-51dfcd41f3f2" xlink:to="loc_us-gaap_ProceedsFromLinesOfCredit_29e71311-db23-4f1b-bb2c-7b61995fe411" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RepaymentsOfUnsecuredDebt_2620ea8e-85d5-41bc-b313-1c172bfbe997" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RepaymentsOfUnsecuredDebt"/>
    <link:calculationArc order="5" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_507531d2-f049-4b79-aca2-51dfcd41f3f2" xlink:to="loc_us-gaap_RepaymentsOfUnsecuredDebt_2620ea8e-85d5-41bc-b313-1c172bfbe997" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsForRepurchaseOfCommonStock_6f60727c-853e-45a2-8f74-4d073117f8fa" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PaymentsForRepurchaseOfCommonStock"/>
    <link:calculationArc order="6" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_507531d2-f049-4b79-aca2-51dfcd41f3f2" xlink:to="loc_us-gaap_PaymentsForRepurchaseOfCommonStock_6f60727c-853e-45a2-8f74-4d073117f8fa" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInOutstandingChecksFinancingActivities_2ad2abee-33cd-4a06-a8df-3ce1bdd71ea9" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncreaseDecreaseInOutstandingChecksFinancingActivities"/>
    <link:calculationArc order="7" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_507531d2-f049-4b79-aca2-51dfcd41f3f2" xlink:to="loc_us-gaap_IncreaseDecreaseInOutstandingChecksFinancingActivities_2ad2abee-33cd-4a06-a8df-3ce1bdd71ea9" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsOfFinancingCosts_b5230199-a87f-44e9-8055-2703e780012d" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PaymentsOfFinancingCosts"/>
    <link:calculationArc order="8" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_507531d2-f049-4b79-aca2-51dfcd41f3f2" xlink:to="loc_us-gaap_PaymentsOfFinancingCosts_b5230199-a87f-44e9-8055-2703e780012d" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsOfDebtExtinguishmentCosts_623a786f-573f-468c-af60-c9dbc60f2f77" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PaymentsOfDebtExtinguishmentCosts"/>
    <link:calculationArc order="9" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_507531d2-f049-4b79-aca2-51dfcd41f3f2" xlink:to="loc_us-gaap_PaymentsOfDebtExtinguishmentCosts_623a786f-573f-468c-af60-c9dbc60f2f77" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromIssuanceOfUnsecuredDebt_bde77658-a6ef-437f-8324-746facb45f99" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ProceedsFromIssuanceOfUnsecuredDebt"/>
    <link:calculationArc order="10" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_507531d2-f049-4b79-aca2-51dfcd41f3f2" xlink:to="loc_us-gaap_ProceedsFromIssuanceOfUnsecuredDebt_bde77658-a6ef-437f-8324-746facb45f99" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_72aa8ccd-63d7-42ce-8426-879a22526f6e" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NetCashProvidedByUsedInOperatingActivities"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsForEnvironmentalLiabilities_6c9d71b7-622e-4562-bf2b-35941b6cace9" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PaymentsForEnvironmentalLiabilities"/>
    <link:calculationArc order="1" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_72aa8ccd-63d7-42ce-8426-879a22526f6e" xlink:to="loc_us-gaap_PaymentsForEnvironmentalLiabilities_6c9d71b7-622e-4562-bf2b-35941b6cace9" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DepreciationDepletionAndAmortization_1d8a99d0-06fa-41af-a91f-9e93c63a4e24" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DepreciationDepletionAndAmortization"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_72aa8ccd-63d7-42ce-8426-879a22526f6e" xlink:to="loc_us-gaap_DepreciationDepletionAndAmortization_1d8a99d0-06fa-41af-a91f-9e93c63a4e24" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredIncomeTaxesAndTaxCredits_8514a2a9-57fe-4c3d-b9a7-64e7139e84a6" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DeferredIncomeTaxesAndTaxCredits"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_72aa8ccd-63d7-42ce-8426-879a22526f6e" xlink:to="loc_us-gaap_DeferredIncomeTaxesAndTaxCredits_8514a2a9-57fe-4c3d-b9a7-64e7139e84a6" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_clh_AccretionOfEnvironmentalLiabilities_8c354efd-9677-43be-8c72-88215882b831" xlink:href="clh-20200930.xsd#clh_AccretionOfEnvironmentalLiabilities"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_72aa8ccd-63d7-42ce-8426-879a22526f6e" xlink:to="loc_clh_AccretionOfEnvironmentalLiabilities_8c354efd-9677-43be-8c72-88215882b831" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetIncomeLoss_8ccca1c6-86b9-47a3-8bbf-cf52ade69d4e" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NetIncomeLoss"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_72aa8ccd-63d7-42ce-8426-879a22526f6e" xlink:to="loc_us-gaap_NetIncomeLoss_8ccca1c6-86b9-47a3-8bbf-cf52ade69d4e" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherNoncashIncomeExpense_7353aef1-5ce7-4c2e-84bc-0f186520f50e" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherNoncashIncomeExpense"/>
    <link:calculationArc order="6" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_72aa8ccd-63d7-42ce-8426-879a22526f6e" xlink:to="loc_us-gaap_OtherNoncashIncomeExpense_7353aef1-5ce7-4c2e-84bc-0f186520f50e" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_GainLossOnSaleOfBusiness_9c10a321-d5e5-4424-8a17-7ef1fee0f497" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_GainLossOnSaleOfBusiness"/>
    <link:calculationArc order="7" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_72aa8ccd-63d7-42ce-8426-879a22526f6e" xlink:to="loc_us-gaap_GainLossOnSaleOfBusiness_9c10a321-d5e5-4424-8a17-7ef1fee0f497" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProvisionForDoubtfulAccounts_23a98c65-c5e6-4472-9639-caba8185f3bb" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ProvisionForDoubtfulAccounts"/>
    <link:calculationArc order="8" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_72aa8ccd-63d7-42ce-8426-879a22526f6e" xlink:to="loc_us-gaap_ProvisionForDoubtfulAccounts_23a98c65-c5e6-4472-9639-caba8185f3bb" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AmortizationOfFinancingCostsAndDiscounts_f1282708-f6b9-4fe2-9101-77ea6c542f63" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AmortizationOfFinancingCostsAndDiscounts"/>
    <link:calculationArc order="9" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_72aa8ccd-63d7-42ce-8426-879a22526f6e" xlink:to="loc_us-gaap_AmortizationOfFinancingCostsAndDiscounts_f1282708-f6b9-4fe2-9101-77ea6c542f63" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInAccountsPayable_f0c199a7-88fe-4ccb-8532-d989d14bd92f" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncreaseDecreaseInAccountsPayable"/>
    <link:calculationArc order="10" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_72aa8ccd-63d7-42ce-8426-879a22526f6e" xlink:to="loc_us-gaap_IncreaseDecreaseInAccountsPayable_f0c199a7-88fe-4ccb-8532-d989d14bd92f" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInInventories_144a00e5-d790-481d-9497-a74e3a19f8c1" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncreaseDecreaseInInventories"/>
    <link:calculationArc order="11" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_72aa8ccd-63d7-42ce-8426-879a22526f6e" xlink:to="loc_us-gaap_IncreaseDecreaseInInventories_144a00e5-d790-481d-9497-a74e3a19f8c1" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInOtherOperatingAssets_5448e6ae-cd74-44a6-aef0-d6593b838273" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncreaseDecreaseInOtherOperatingAssets"/>
    <link:calculationArc order="12" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_72aa8ccd-63d7-42ce-8426-879a22526f6e" xlink:to="loc_us-gaap_IncreaseDecreaseInOtherOperatingAssets_5448e6ae-cd74-44a6-aef0-d6593b838273" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensation_ff90d71c-8688-48bd-a5bc-a919507dd773" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensation"/>
    <link:calculationArc order="13" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_72aa8ccd-63d7-42ce-8426-879a22526f6e" xlink:to="loc_us-gaap_ShareBasedCompensation_ff90d71c-8688-48bd-a5bc-a919507dd773" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherIncreaseDecreaseInEnvironmentalLiabilities_f635c8b8-3453-47d6-81f9-a6a10e917b46" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherIncreaseDecreaseInEnvironmentalLiabilities"/>
    <link:calculationArc order="14" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_72aa8ccd-63d7-42ce-8426-879a22526f6e" xlink:to="loc_us-gaap_OtherIncreaseDecreaseInEnvironmentalLiabilities_f635c8b8-3453-47d6-81f9-a6a10e917b46" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInOtherOperatingLiabilities_77515263-8182-463a-beb3-36dbf51b7711" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncreaseDecreaseInOtherOperatingLiabilities"/>
    <link:calculationArc order="15" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_72aa8ccd-63d7-42ce-8426-879a22526f6e" xlink:to="loc_us-gaap_IncreaseDecreaseInOtherOperatingLiabilities_77515263-8182-463a-beb3-36dbf51b7711" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInAccountsReceivable_167e4bc9-867b-4523-902a-2f927597c1e7" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncreaseDecreaseInAccountsReceivable"/>
    <link:calculationArc order="16" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_72aa8ccd-63d7-42ce-8426-879a22526f6e" xlink:to="loc_us-gaap_IncreaseDecreaseInAccountsReceivable_167e4bc9-867b-4523-902a-2f927597c1e7" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_GainsLossesOnExtinguishmentOfDebt_0ec26958-0f9f-4890-aa0a-040bc24f247e" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_GainsLossesOnExtinguishmentOfDebt"/>
    <link:calculationArc order="17" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_72aa8ccd-63d7-42ce-8426-879a22526f6e" xlink:to="loc_us-gaap_GainsLossesOnExtinguishmentOfDebt_0ec26958-0f9f-4890-aa0a-040bc24f247e" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect_f50dd53e-f848-4dab-88b0-f0b26dd9574f" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EffectOfExchangeRateOnCashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_069f2d99-9cc5-4ae5-bf73-43d952ca9d92" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EffectOfExchangeRateOnCashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect_f50dd53e-f848-4dab-88b0-f0b26dd9574f" xlink:to="loc_us-gaap_EffectOfExchangeRateOnCashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_069f2d99-9cc5-4ae5-bf73-43d952ca9d92" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_13b5805c-fca4-44ae-8c9f-34c55f5bfa67" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NetCashProvidedByUsedInFinancingActivities"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect_f50dd53e-f848-4dab-88b0-f0b26dd9574f" xlink:to="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_13b5805c-fca4-44ae-8c9f-34c55f5bfa67" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_8671d653-8409-4477-bb87-595c4f32db96" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NetCashProvidedByUsedInOperatingActivities"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect_f50dd53e-f848-4dab-88b0-f0b26dd9574f" xlink:to="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_8671d653-8409-4477-bb87-595c4f32db96" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_20bf4c72-191c-4458-95af-6da10817c5f8" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NetCashProvidedByUsedInInvestingActivities"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect_f50dd53e-f848-4dab-88b0-f0b26dd9574f" xlink:to="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_20bf4c72-191c-4458-95af-6da10817c5f8" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_e695246d-9999-40c9-9d61-1b0a64cac71e" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NetCashProvidedByUsedInInvestingActivities"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsToAcquireAvailableForSaleSecuritiesDebt_cc35fac3-120d-4aad-a778-138eca663382" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PaymentsToAcquireAvailableForSaleSecuritiesDebt"/>
    <link:calculationArc order="1" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_e695246d-9999-40c9-9d61-1b0a64cac71e" xlink:to="loc_us-gaap_PaymentsToAcquireAvailableForSaleSecuritiesDebt_cc35fac3-120d-4aad-a778-138eca663382" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsToAcquireBusinessesNetOfCashAcquired_18d0f5ee-5b67-4594-b19d-cb8a899602eb" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PaymentsToAcquireBusinessesNetOfCashAcquired"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_e695246d-9999-40c9-9d61-1b0a64cac71e" xlink:to="loc_us-gaap_PaymentsToAcquireBusinessesNetOfCashAcquired_18d0f5ee-5b67-4594-b19d-cb8a899602eb" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsToAcquireIntangibleAssets_189561ef-2fc0-42d5-99ff-615232527324" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PaymentsToAcquireIntangibleAssets"/>
    <link:calculationArc order="3" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_e695246d-9999-40c9-9d61-1b0a64cac71e" xlink:to="loc_us-gaap_PaymentsToAcquireIntangibleAssets_189561ef-2fc0-42d5-99ff-615232527324" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsToAcquirePropertyPlantAndEquipment_839f4708-d69b-4ae6-84cb-aeed18cf5111" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PaymentsToAcquirePropertyPlantAndEquipment"/>
    <link:calculationArc order="4" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_e695246d-9999-40c9-9d61-1b0a64cac71e" xlink:to="loc_us-gaap_PaymentsToAcquirePropertyPlantAndEquipment_839f4708-d69b-4ae6-84cb-aeed18cf5111" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromSaleOfAvailableForSaleSecuritiesDebt_3293f552-c926-4fd5-b5eb-1eb5b9c4e16c" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ProceedsFromSaleOfAvailableForSaleSecuritiesDebt"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_e695246d-9999-40c9-9d61-1b0a64cac71e" xlink:to="loc_us-gaap_ProceedsFromSaleOfAvailableForSaleSecuritiesDebt_3293f552-c926-4fd5-b5eb-1eb5b9c4e16c" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromSaleOfProductiveAssets_bf89d881-9dff-4ddb-b2ac-49f8cce99b27" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ProceedsFromSaleOfProductiveAssets"/>
    <link:calculationArc order="6" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_e695246d-9999-40c9-9d61-1b0a64cac71e" xlink:to="loc_us-gaap_ProceedsFromSaleOfProductiveAssets_bf89d881-9dff-4ddb-b2ac-49f8cce99b27" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromDivestitureOfBusinesses_aa3f4d2c-de60-45ed-afb4-67d4956b409f" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ProceedsFromDivestitureOfBusinesses"/>
    <link:calculationArc order="7" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_e695246d-9999-40c9-9d61-1b0a64cac71e" xlink:to="loc_us-gaap_ProceedsFromDivestitureOfBusinesses_aa3f4d2c-de60-45ed-afb4-67d4956b409f" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.cleanharbors.com/role/UNAUDITEDCONSOLIDATEDSTATEMENTSOFSTOCKHOLDERSEQUITY" xlink:type="simple" xlink:href="clh-20200930.xsd#UNAUDITEDCONSOLIDATEDSTATEMENTSOFSTOCKHOLDERSEQUITY"/>
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/UNAUDITEDCONSOLIDATEDSTATEMENTSOFSTOCKHOLDERSEQUITY" xlink:type="extended"/>
  <link:roleRef roleURI="http://www.cleanharbors.com/role/BASISOFPRESENTATION" xlink:type="simple" xlink:href="clh-20200930.xsd#BASISOFPRESENTATION"/>
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/BASISOFPRESENTATION" xlink:type="extended"/>
  <link:roleRef roleURI="http://www.cleanharbors.com/role/SIGNIFICANTACCOUNTINGPOLICIES" xlink:type="simple" xlink:href="clh-20200930.xsd#SIGNIFICANTACCOUNTINGPOLICIES"/>
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/SIGNIFICANTACCOUNTINGPOLICIES" xlink:type="extended"/>
  <link:roleRef roleURI="http://www.cleanharbors.com/role/SIGNIFICANTACCOUNTINGPOLICIESPolicies" xlink:type="simple" xlink:href="clh-20200930.xsd#SIGNIFICANTACCOUNTINGPOLICIESPolicies"/>
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/SIGNIFICANTACCOUNTINGPOLICIESPolicies" xlink:type="extended"/>
  <link:roleRef roleURI="http://www.cleanharbors.com/role/SIGNIFICANTACCOUNTINGPOLICIESDetails" xlink:type="simple" xlink:href="clh-20200930.xsd#SIGNIFICANTACCOUNTINGPOLICIESDetails"/>
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/SIGNIFICANTACCOUNTINGPOLICIESDetails" xlink:type="extended"/>
  <link:roleRef roleURI="http://www.cleanharbors.com/role/REVENUES" xlink:type="simple" xlink:href="clh-20200930.xsd#REVENUES"/>
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/REVENUES" xlink:type="extended"/>
  <link:roleRef roleURI="http://www.cleanharbors.com/role/REVENUESTables" xlink:type="simple" xlink:href="clh-20200930.xsd#REVENUESTables"/>
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/REVENUESTables" xlink:type="extended"/>
  <link:roleRef roleURI="http://www.cleanharbors.com/role/REVENUESDisaggregationofRevenueDetails" xlink:type="simple" xlink:href="clh-20200930.xsd#REVENUESDisaggregationofRevenueDetails"/>
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/REVENUESDisaggregationofRevenueDetails" xlink:type="extended"/>
  <link:roleRef roleURI="http://www.cleanharbors.com/role/REVENUESContractBalancesDetails" xlink:type="simple" xlink:href="clh-20200930.xsd#REVENUESContractBalancesDetails"/>
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/REVENUESContractBalancesDetails" xlink:type="extended"/>
  <link:roleRef roleURI="http://www.cleanharbors.com/role/REVENUESNarrativeDetails" xlink:type="simple" xlink:href="clh-20200930.xsd#REVENUESNarrativeDetails"/>
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/REVENUESNarrativeDetails" xlink:type="extended"/>
  <link:roleRef roleURI="http://www.cleanharbors.com/role/BUSINESSCOMBINATIONS" xlink:type="simple" xlink:href="clh-20200930.xsd#BUSINESSCOMBINATIONS"/>
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/BUSINESSCOMBINATIONS" xlink:type="extended"/>
  <link:roleRef roleURI="http://www.cleanharbors.com/role/BUSINESSCOMBINATIONSDetails" xlink:type="simple" xlink:href="clh-20200930.xsd#BUSINESSCOMBINATIONSDetails"/>
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/BUSINESSCOMBINATIONSDetails" xlink:type="extended"/>
  <link:roleRef roleURI="http://www.cleanharbors.com/role/INVENTORIESANDSUPPLIES" xlink:type="simple" xlink:href="clh-20200930.xsd#INVENTORIESANDSUPPLIES"/>
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/INVENTORIESANDSUPPLIES" xlink:type="extended"/>
  <link:roleRef roleURI="http://www.cleanharbors.com/role/INVENTORIESANDSUPPLIESTables" xlink:type="simple" xlink:href="clh-20200930.xsd#INVENTORIESANDSUPPLIESTables"/>
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/INVENTORIESANDSUPPLIESTables" xlink:type="extended"/>
  <link:roleRef roleURI="http://www.cleanharbors.com/role/INVENTORIESANDSUPPLIESDetails" xlink:type="simple" xlink:href="clh-20200930.xsd#INVENTORIESANDSUPPLIESDetails"/>
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/INVENTORIESANDSUPPLIESDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_Supplies_240f859f-69af-4794-b840-18c904b3951c" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_Supplies"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InventoryCrudeOilProductsAndMerchandise_cf7cc7e1-5424-42ab-a6cd-e1ce78c04b60" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_InventoryCrudeOilProductsAndMerchandise"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Supplies_240f859f-69af-4794-b840-18c904b3951c" xlink:to="loc_us-gaap_InventoryCrudeOilProductsAndMerchandise_cf7cc7e1-5424-42ab-a6cd-e1ce78c04b60" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_clh_EnergyRelatedInventorySuppliesAndDrums_3f8b440f-f919-44d9-aaf3-3eb078334bd7" xlink:href="clh-20200930.xsd#clh_EnergyRelatedInventorySuppliesAndDrums"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Supplies_240f859f-69af-4794-b840-18c904b3951c" xlink:to="loc_clh_EnergyRelatedInventorySuppliesAndDrums_3f8b440f-f919-44d9-aaf3-3eb078334bd7" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EnergyRelatedInventoryChemicals_7624debb-4391-43c7-99f0-c41f4ef66108" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EnergyRelatedInventoryChemicals"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Supplies_240f859f-69af-4794-b840-18c904b3951c" xlink:to="loc_us-gaap_EnergyRelatedInventoryChemicals_7624debb-4391-43c7-99f0-c41f4ef66108" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_clh_EnergyRelatedInventoryOther_2984c5af-ed00-46f2-b53b-c4b87a1ae80f" xlink:href="clh-20200930.xsd#clh_EnergyRelatedInventoryOther"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Supplies_240f859f-69af-4794-b840-18c904b3951c" xlink:to="loc_clh_EnergyRelatedInventoryOther_2984c5af-ed00-46f2-b53b-c4b87a1ae80f" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.cleanharbors.com/role/PROPERTYPLANTANDEQUIPMENT" xlink:type="simple" xlink:href="clh-20200930.xsd#PROPERTYPLANTANDEQUIPMENT"/>
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/PROPERTYPLANTANDEQUIPMENT" xlink:type="extended"/>
  <link:roleRef roleURI="http://www.cleanharbors.com/role/PROPERTYPLANTANDEQUIPMENTTables" xlink:type="simple" xlink:href="clh-20200930.xsd#PROPERTYPLANTANDEQUIPMENTTables"/>
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/PROPERTYPLANTANDEQUIPMENTTables" xlink:type="extended"/>
  <link:roleRef roleURI="http://www.cleanharbors.com/role/PROPERTYPLANTANDEQUIPMENTScheduleofPropertyPlantandEquipmentDetails" xlink:type="simple" xlink:href="clh-20200930.xsd#PROPERTYPLANTANDEQUIPMENTScheduleofPropertyPlantandEquipmentDetails"/>
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/PROPERTYPLANTANDEQUIPMENTScheduleofPropertyPlantandEquipmentDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentAndFinanceLeaseRightOfUseAssetAfterAccumulatedDepreciationAndAmortization_c4496601-7f3d-4d47-a369-9456b4539a0c" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PropertyPlantAndEquipmentAndFinanceLeaseRightOfUseAssetAfterAccumulatedDepreciationAndAmortization"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentAndFinanceLeaseRightOfUseAssetBeforeAccumulatedDepreciationAndAmortization_7e43b089-fc44-4075-9b2d-9720937f3d87" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PropertyPlantAndEquipmentAndFinanceLeaseRightOfUseAssetBeforeAccumulatedDepreciationAndAmortization"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentAndFinanceLeaseRightOfUseAssetAfterAccumulatedDepreciationAndAmortization_c4496601-7f3d-4d47-a369-9456b4539a0c" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentAndFinanceLeaseRightOfUseAssetBeforeAccumulatedDepreciationAndAmortization_7e43b089-fc44-4075-9b2d-9720937f3d87" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentAndFinanceLeaseRightOfUseAssetAccumulatedDepreciationAndAmortization_46e98abb-8dbf-4078-b327-b307bb23c749" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PropertyPlantAndEquipmentAndFinanceLeaseRightOfUseAssetAccumulatedDepreciationAndAmortization"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentAndFinanceLeaseRightOfUseAssetAfterAccumulatedDepreciationAndAmortization_c4496601-7f3d-4d47-a369-9456b4539a0c" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentAndFinanceLeaseRightOfUseAssetAccumulatedDepreciationAndAmortization_46e98abb-8dbf-4078-b327-b307bb23c749" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.cleanharbors.com/role/PROPERTYPLANTANDEQUIPMENTNarrativeDetails" xlink:type="simple" xlink:href="clh-20200930.xsd#PROPERTYPLANTANDEQUIPMENTNarrativeDetails"/>
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/PROPERTYPLANTANDEQUIPMENTNarrativeDetails" xlink:type="extended"/>
  <link:roleRef roleURI="http://www.cleanharbors.com/role/GOODWILLANDOTHERINTANGIBLEASSETS" xlink:type="simple" xlink:href="clh-20200930.xsd#GOODWILLANDOTHERINTANGIBLEASSETS"/>
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/GOODWILLANDOTHERINTANGIBLEASSETS" xlink:type="extended"/>
  <link:roleRef roleURI="http://www.cleanharbors.com/role/GOODWILLANDOTHERINTANGIBLEASSETSTables" xlink:type="simple" xlink:href="clh-20200930.xsd#GOODWILLANDOTHERINTANGIBLEASSETSTables"/>
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/GOODWILLANDOTHERINTANGIBLEASSETSTables" xlink:type="extended"/>
  <link:roleRef roleURI="http://www.cleanharbors.com/role/GOODWILLANDOTHERINTANGIBLEASSETSRollforwardofGoodwillDetails" xlink:type="simple" xlink:href="clh-20200930.xsd#GOODWILLANDOTHERINTANGIBLEASSETSRollforwardofGoodwillDetails"/>
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/GOODWILLANDOTHERINTANGIBLEASSETSRollforwardofGoodwillDetails" xlink:type="extended"/>
  <link:roleRef roleURI="http://www.cleanharbors.com/role/GOODWILLANDOTHERINTANGIBLEASSETSAmortizableOtherIntangibleAssetsDetails" xlink:type="simple" xlink:href="clh-20200930.xsd#GOODWILLANDOTHERINTANGIBLEASSETSAmortizableOtherIntangibleAssetsDetails"/>
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/GOODWILLANDOTHERINTANGIBLEASSETSAmortizableOtherIntangibleAssetsDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IntangibleAssetsGrossExcludingGoodwill_593e7537-969e-425c-b039-81a39dfb2d42" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IntangibleAssetsGrossExcludingGoodwill"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsGross_e584c37a-8690-4ecc-b9d6-4b09d9d2d44e" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsGross"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IntangibleAssetsGrossExcludingGoodwill_593e7537-969e-425c-b039-81a39dfb2d42" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsGross_e584c37a-8690-4ecc-b9d6-4b09d9d2d44e" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IndefiniteLivedIntangibleAssetsExcludingGoodwill_9cfdbd49-3850-4028-b840-034f859b2f06" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IndefiniteLivedIntangibleAssetsExcludingGoodwill"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IntangibleAssetsGrossExcludingGoodwill_593e7537-969e-425c-b039-81a39dfb2d42" xlink:to="loc_us-gaap_IndefiniteLivedIntangibleAssetsExcludingGoodwill_9cfdbd49-3850-4028-b840-034f859b2f06" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IntangibleAssetsNetExcludingGoodwill_ec5c1b0a-3e7e-4270-b827-84b8dca485a6" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IntangibleAssetsNetExcludingGoodwill"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsNet_efced5cb-076d-4b63-9ac9-cdbde5384371" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsNet"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IntangibleAssetsNetExcludingGoodwill_ec5c1b0a-3e7e-4270-b827-84b8dca485a6" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsNet_efced5cb-076d-4b63-9ac9-cdbde5384371" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IndefiniteLivedIntangibleAssetsExcludingGoodwill_26db7f6b-fee9-4f27-8b8a-30ac3602fefb" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IndefiniteLivedIntangibleAssetsExcludingGoodwill"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IntangibleAssetsNetExcludingGoodwill_ec5c1b0a-3e7e-4270-b827-84b8dca485a6" xlink:to="loc_us-gaap_IndefiniteLivedIntangibleAssetsExcludingGoodwill_26db7f6b-fee9-4f27-8b8a-30ac3602fefb" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsNet_af41d72f-54f2-49bd-b655-7a44acb4abb8" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsNet"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsGross_ae4079b7-5c34-455f-ad66-90b2bb499b49" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsGross"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsNet_af41d72f-54f2-49bd-b655-7a44acb4abb8" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsGross_ae4079b7-5c34-455f-ad66-90b2bb499b49" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAccumulatedAmortization_a6fa33e4-3cbc-4162-9b56-ab62461bd3e7" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsAccumulatedAmortization"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsNet_af41d72f-54f2-49bd-b655-7a44acb4abb8" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsAccumulatedAmortization_a6fa33e4-3cbc-4162-9b56-ab62461bd3e7" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.cleanharbors.com/role/GOODWILLANDOTHERINTANGIBLEASSETSAmortizableOtherIntangibleAssetsDetails_1" xlink:type="simple" xlink:href="clh-20200930.xsd#GOODWILLANDOTHERINTANGIBLEASSETSAmortizableOtherIntangibleAssetsDetails_1"/>
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/GOODWILLANDOTHERINTANGIBLEASSETSAmortizableOtherIntangibleAssetsDetails_1" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IntangibleAssetsNetExcludingGoodwill_26d0df87-ef37-47ff-8d57-7b8291d44b52" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IntangibleAssetsNetExcludingGoodwill"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IntangibleAssetsGrossExcludingGoodwill_187c9e26-593c-49a9-95f7-b61d91bdacbd" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IntangibleAssetsGrossExcludingGoodwill"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IntangibleAssetsNetExcludingGoodwill_26d0df87-ef37-47ff-8d57-7b8291d44b52" xlink:to="loc_us-gaap_IntangibleAssetsGrossExcludingGoodwill_187c9e26-593c-49a9-95f7-b61d91bdacbd" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAccumulatedAmortization_ed1544a7-3f51-4ee7-add3-587cab42a617" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsAccumulatedAmortization"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IntangibleAssetsNetExcludingGoodwill_26d0df87-ef37-47ff-8d57-7b8291d44b52" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsAccumulatedAmortization_ed1544a7-3f51-4ee7-add3-587cab42a617" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.cleanharbors.com/role/GOODWILLANDOTHERINTANGIBLEASSETSNarrativeDetails" xlink:type="simple" xlink:href="clh-20200930.xsd#GOODWILLANDOTHERINTANGIBLEASSETSNarrativeDetails"/>
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/GOODWILLANDOTHERINTANGIBLEASSETSNarrativeDetails" xlink:type="extended"/>
  <link:roleRef roleURI="http://www.cleanharbors.com/role/GOODWILLANDOTHERINTANGIBLEASSETSExpectedFutureAmortizationDetails" xlink:type="simple" xlink:href="clh-20200930.xsd#GOODWILLANDOTHERINTANGIBLEASSETSExpectedFutureAmortizationDetails"/>
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/GOODWILLANDOTHERINTANGIBLEASSETSExpectedFutureAmortizationDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsNet_c46265e7-caf5-47d6-a46c-883f2abf8355" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsNet"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFour_66f77b65-932c-4684-b42b-c4b22ebdf60e" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFour"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsNet_c46265e7-caf5-47d6-a46c-883f2abf8355" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFour_66f77b65-932c-4684-b42b-c4b22ebdf60e" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearTwo_623c074c-6ca6-4a12-97db-919577c5b95d" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearTwo"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsNet_c46265e7-caf5-47d6-a46c-883f2abf8355" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearTwo_623c074c-6ca6-4a12-97db-919577c5b95d" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearThree_3f0ddc26-ecdb-4518-bc83-9fb77dff1ffe" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearThree"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsNet_c46265e7-caf5-47d6-a46c-883f2abf8355" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearThree_3f0ddc26-ecdb-4518-bc83-9fb77dff1ffe" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_clh_FiniteLivedIntangibleAssetExpectedAmortizationAfterYearFour_de7c9879-acf9-4fe9-a6fa-ead7dd16d1a1" xlink:href="clh-20200930.xsd#clh_FiniteLivedIntangibleAssetExpectedAmortizationAfterYearFour"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsNet_c46265e7-caf5-47d6-a46c-883f2abf8355" xlink:to="loc_clh_FiniteLivedIntangibleAssetExpectedAmortizationAfterYearFour_de7c9879-acf9-4fe9-a6fa-ead7dd16d1a1" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseNextTwelveMonths_eb9f4cfd-e1fc-44ac-926f-232dcc37fe18" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseNextTwelveMonths"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsNet_c46265e7-caf5-47d6-a46c-883f2abf8355" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseNextTwelveMonths_eb9f4cfd-e1fc-44ac-926f-232dcc37fe18" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseRemainderOfFiscalYear_a3b0a50a-69a2-452b-8871-8b39d3058731" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseRemainderOfFiscalYear"/>
    <link:calculationArc order="6" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsNet_c46265e7-caf5-47d6-a46c-883f2abf8355" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseRemainderOfFiscalYear_a3b0a50a-69a2-452b-8871-8b39d3058731" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.cleanharbors.com/role/ACCRUEDEXPENSES" xlink:type="simple" xlink:href="clh-20200930.xsd#ACCRUEDEXPENSES"/>
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/ACCRUEDEXPENSES" xlink:type="extended"/>
  <link:roleRef roleURI="http://www.cleanharbors.com/role/ACCRUEDEXPENSESTables" xlink:type="simple" xlink:href="clh-20200930.xsd#ACCRUEDEXPENSESTables"/>
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/ACCRUEDEXPENSESTables" xlink:type="extended"/>
  <link:roleRef roleURI="http://www.cleanharbors.com/role/ACCRUEDEXPENSESDetails" xlink:type="simple" xlink:href="clh-20200930.xsd#ACCRUEDEXPENSESDetails"/>
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/ACCRUEDEXPENSESDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccruedLiabilitiesCurrent_62b4ba4f-82af-4d9b-9e8e-724f2c4922db" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AccruedLiabilitiesCurrent"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccruedInsuranceCurrent_a57ca4dd-134c-4e45-a2d1-78f186ee74bc" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AccruedInsuranceCurrent"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AccruedLiabilitiesCurrent_62b4ba4f-82af-4d9b-9e8e-724f2c4922db" xlink:to="loc_us-gaap_AccruedInsuranceCurrent_a57ca4dd-134c-4e45-a2d1-78f186ee74bc" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestPayableCurrent_98d133ac-8429-4738-a7e0-7a329db2effe" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_InterestPayableCurrent"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AccruedLiabilitiesCurrent_62b4ba4f-82af-4d9b-9e8e-724f2c4922db" xlink:to="loc_us-gaap_InterestPayableCurrent_98d133ac-8429-4738-a7e0-7a329db2effe" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EmployeeRelatedLiabilitiesCurrent_6ea96743-02f6-4ac0-89a6-e1eb4871d1b8" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EmployeeRelatedLiabilitiesCurrent"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AccruedLiabilitiesCurrent_62b4ba4f-82af-4d9b-9e8e-724f2c4922db" xlink:to="loc_us-gaap_EmployeeRelatedLiabilitiesCurrent_6ea96743-02f6-4ac0-89a6-e1eb4871d1b8" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_TaxesPayableCurrent_b2f0ea0a-d0bc-4062-941f-df5107b56391" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_TaxesPayableCurrent"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AccruedLiabilitiesCurrent_62b4ba4f-82af-4d9b-9e8e-724f2c4922db" xlink:to="loc_us-gaap_TaxesPayableCurrent_b2f0ea0a-d0bc-4062-941f-df5107b56391" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherAccruedLiabilitiesCurrent_ba8e30f1-8aa9-44b9-b663-8417c7d6602a" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherAccruedLiabilitiesCurrent"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AccruedLiabilitiesCurrent_62b4ba4f-82af-4d9b-9e8e-724f2c4922db" xlink:to="loc_us-gaap_OtherAccruedLiabilitiesCurrent_ba8e30f1-8aa9-44b9-b663-8417c7d6602a" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DerivativeLiabilitiesCurrent_0c6b13a2-bf5d-482f-bf42-beeac0f0eafc" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DerivativeLiabilitiesCurrent"/>
    <link:calculationArc order="6" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AccruedLiabilitiesCurrent_62b4ba4f-82af-4d9b-9e8e-724f2c4922db" xlink:to="loc_us-gaap_DerivativeLiabilitiesCurrent_0c6b13a2-bf5d-482f-bf42-beeac0f0eafc" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.cleanharbors.com/role/CLOSUREANDPOSTCLOSURELIABILITIES" xlink:type="simple" xlink:href="clh-20200930.xsd#CLOSUREANDPOSTCLOSURELIABILITIES"/>
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/CLOSUREANDPOSTCLOSURELIABILITIES" xlink:type="extended"/>
  <link:roleRef roleURI="http://www.cleanharbors.com/role/CLOSUREANDPOSTCLOSURELIABILITIESTables" xlink:type="simple" xlink:href="clh-20200930.xsd#CLOSUREANDPOSTCLOSURELIABILITIESTables"/>
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/CLOSUREANDPOSTCLOSURELIABILITIESTables" xlink:type="extended"/>
  <link:roleRef roleURI="http://www.cleanharbors.com/role/CLOSUREANDPOSTCLOSURELIABILITIESDetails" xlink:type="simple" xlink:href="clh-20200930.xsd#CLOSUREANDPOSTCLOSURELIABILITIESDetails"/>
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/CLOSUREANDPOSTCLOSURELIABILITIESDetails" xlink:type="extended"/>
  <link:roleRef roleURI="http://www.cleanharbors.com/role/REMEDIALLIABILITIES" xlink:type="simple" xlink:href="clh-20200930.xsd#REMEDIALLIABILITIES"/>
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/REMEDIALLIABILITIES" xlink:type="extended"/>
  <link:roleRef roleURI="http://www.cleanharbors.com/role/REMEDIALLIABILITIESTables" xlink:type="simple" xlink:href="clh-20200930.xsd#REMEDIALLIABILITIESTables"/>
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/REMEDIALLIABILITIESTables" xlink:type="extended"/>
  <link:roleRef roleURI="http://www.cleanharbors.com/role/REMEDIALLIABILITIESDetails" xlink:type="simple" xlink:href="clh-20200930.xsd#REMEDIALLIABILITIESDetails"/>
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/REMEDIALLIABILITIESDetails" xlink:type="extended"/>
  <link:roleRef roleURI="http://www.cleanharbors.com/role/FINANCINGARRANGEMENTS" xlink:type="simple" xlink:href="clh-20200930.xsd#FINANCINGARRANGEMENTS"/>
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/FINANCINGARRANGEMENTS" xlink:type="extended"/>
  <link:roleRef roleURI="http://www.cleanharbors.com/role/FINANCINGARRANGEMENTSTables" xlink:type="simple" xlink:href="clh-20200930.xsd#FINANCINGARRANGEMENTSTables"/>
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/FINANCINGARRANGEMENTSTables" xlink:type="extended"/>
  <link:roleRef roleURI="http://www.cleanharbors.com/role/FINANCINGARRANGEMENTSSummaryofFinancingArrangementsDetails" xlink:type="simple" xlink:href="clh-20200930.xsd#FINANCINGARRANGEMENTSSummaryofFinancingArrangementsDetails"/>
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/FINANCINGARRANGEMENTSSummaryofFinancingArrangementsDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongTermDebtNoncurrent_e90b2210-fbfc-49a2-b781-e2b383a7e93c" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LongTermDebtNoncurrent"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentCarryingAmount_afa92cfd-9be6-4ca0-9cb8-9bad2c216180" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtInstrumentCarryingAmount"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LongTermDebtNoncurrent_e90b2210-fbfc-49a2-b781-e2b383a7e93c" xlink:to="loc_us-gaap_DebtInstrumentCarryingAmount_afa92cfd-9be6-4ca0-9cb8-9bad2c216180" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredFinanceCostsNet_bbe1afa9-f012-4ab6-be35-77071b8d59d8" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DeferredFinanceCostsNet"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LongTermDebtNoncurrent_e90b2210-fbfc-49a2-b781-e2b383a7e93c" xlink:to="loc_us-gaap_DeferredFinanceCostsNet_bbe1afa9-f012-4ab6-be35-77071b8d59d8" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.cleanharbors.com/role/FINANCINGARRANGEMENTSNarrativeDetails" xlink:type="simple" xlink:href="clh-20200930.xsd#FINANCINGARRANGEMENTSNarrativeDetails"/>
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/FINANCINGARRANGEMENTSNarrativeDetails" xlink:type="extended"/>
  <link:roleRef roleURI="http://www.cleanharbors.com/role/INCOMETAXES" xlink:type="simple" xlink:href="clh-20200930.xsd#INCOMETAXES"/>
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/INCOMETAXES" xlink:type="extended"/>
  <link:roleRef roleURI="http://www.cleanharbors.com/role/INCOMETAXESDetails" xlink:type="simple" xlink:href="clh-20200930.xsd#INCOMETAXESDetails"/>
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/INCOMETAXESDetails" xlink:type="extended"/>
  <link:roleRef roleURI="http://www.cleanharbors.com/role/EARNINGSPERSHARE" xlink:type="simple" xlink:href="clh-20200930.xsd#EARNINGSPERSHARE"/>
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/EARNINGSPERSHARE" xlink:type="extended"/>
  <link:roleRef roleURI="http://www.cleanharbors.com/role/EARNINGSPERSHARETables" xlink:type="simple" xlink:href="clh-20200930.xsd#EARNINGSPERSHARETables"/>
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/EARNINGSPERSHARETables" xlink:type="extended"/>
  <link:roleRef roleURI="http://www.cleanharbors.com/role/EARNINGSPERSHAREComputationofBasicandDilutedEarningsPerShareDetails" xlink:type="simple" xlink:href="clh-20200930.xsd#EARNINGSPERSHAREComputationofBasicandDilutedEarningsPerShareDetails"/>
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/EARNINGSPERSHAREComputationofBasicandDilutedEarningsPerShareDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding_3ee70767-caa5-43d2-b08c-627b1ba55e95" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_WeightedAverageNumberOfSharesOutstandingBasic_0e39c933-4c4f-4bd8-8b7a-7b7fd5a3f27b" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_WeightedAverageNumberOfSharesOutstandingBasic"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding_3ee70767-caa5-43d2-b08c-627b1ba55e95" xlink:to="loc_us-gaap_WeightedAverageNumberOfSharesOutstandingBasic_0e39c933-4c4f-4bd8-8b7a-7b7fd5a3f27b" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncrementalCommonSharesAttributableToShareBasedPaymentArrangements_33379434-fda7-41aa-b573-aee47d3f1108" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncrementalCommonSharesAttributableToShareBasedPaymentArrangements"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding_3ee70767-caa5-43d2-b08c-627b1ba55e95" xlink:to="loc_us-gaap_IncrementalCommonSharesAttributableToShareBasedPaymentArrangements_33379434-fda7-41aa-b573-aee47d3f1108" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.cleanharbors.com/role/EARNINGSPERSHARENarrativeDetails" xlink:type="simple" xlink:href="clh-20200930.xsd#EARNINGSPERSHARENarrativeDetails"/>
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/EARNINGSPERSHARENarrativeDetails" xlink:type="extended"/>
  <link:roleRef roleURI="http://www.cleanharbors.com/role/ACCUMULATEDOTHERCOMPREHENSIVELOSS" xlink:type="simple" xlink:href="clh-20200930.xsd#ACCUMULATEDOTHERCOMPREHENSIVELOSS"/>
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/ACCUMULATEDOTHERCOMPREHENSIVELOSS" xlink:type="extended"/>
  <link:roleRef roleURI="http://www.cleanharbors.com/role/ACCUMULATEDOTHERCOMPREHENSIVELOSSTables" xlink:type="simple" xlink:href="clh-20200930.xsd#ACCUMULATEDOTHERCOMPREHENSIVELOSSTables"/>
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/ACCUMULATEDOTHERCOMPREHENSIVELOSSTables" xlink:type="extended"/>
  <link:roleRef roleURI="http://www.cleanharbors.com/role/ACCUMULATEDOTHERCOMPREHENSIVELOSSChangesinAccumulatedOtherComprehensiveLossbyComponentDetails" xlink:type="simple" xlink:href="clh-20200930.xsd#ACCUMULATEDOTHERCOMPREHENSIVELOSSChangesinAccumulatedOtherComprehensiveLossbyComponentDetails"/>
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/ACCUMULATEDOTHERCOMPREHENSIVELOSSChangesinAccumulatedOtherComprehensiveLossbyComponentDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent_27f970c8-7530-497e-be4b-22610e44bb95" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OciBeforeReclassificationsBeforeTaxAttributableToParent_10e571e5-b8eb-4a55-89c1-ae090e78773c" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OciBeforeReclassificationsBeforeTaxAttributableToParent"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent_27f970c8-7530-497e-be4b-22610e44bb95" xlink:to="loc_us-gaap_OciBeforeReclassificationsBeforeTaxAttributableToParent_10e571e5-b8eb-4a55-89c1-ae090e78773c" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ReclassificationFromAociCurrentPeriodNetOfTaxAttributableToParent_dd7c02ce-b2da-4917-a173-94786138e43d" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ReclassificationFromAociCurrentPeriodNetOfTaxAttributableToParent"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent_27f970c8-7530-497e-be4b-22610e44bb95" xlink:to="loc_us-gaap_ReclassificationFromAociCurrentPeriodNetOfTaxAttributableToParent_dd7c02ce-b2da-4917-a173-94786138e43d" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossTaxPortionAttributableToParent1_e2bf82db-dc33-414d-8e7e-aa0c5240a38c" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossTaxPortionAttributableToParent1"/>
    <link:calculationArc order="3" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent_27f970c8-7530-497e-be4b-22610e44bb95" xlink:to="loc_us-gaap_OtherComprehensiveIncomeLossTaxPortionAttributableToParent1_e2bf82db-dc33-414d-8e7e-aa0c5240a38c" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.cleanharbors.com/role/ACCUMULATEDOTHERCOMPREHENSIVELOSSReclassifiedOutofAccumulatedOtherComprehensiveLossDetails" xlink:type="simple" xlink:href="clh-20200930.xsd#ACCUMULATEDOTHERCOMPREHENSIVELOSSReclassifiedOutofAccumulatedOtherComprehensiveLossDetails"/>
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/ACCUMULATEDOTHERCOMPREHENSIVELOSSReclassifiedOutofAccumulatedOtherComprehensiveLossDetails" xlink:type="extended"/>
  <link:roleRef roleURI="http://www.cleanharbors.com/role/STOCKBASEDCOMPENSATION" xlink:type="simple" xlink:href="clh-20200930.xsd#STOCKBASEDCOMPENSATION"/>
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/STOCKBASEDCOMPENSATION" xlink:type="extended"/>
  <link:roleRef roleURI="http://www.cleanharbors.com/role/STOCKBASEDCOMPENSATIONTables" xlink:type="simple" xlink:href="clh-20200930.xsd#STOCKBASEDCOMPENSATIONTables"/>
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/STOCKBASEDCOMPENSATIONTables" xlink:type="extended"/>
  <link:roleRef roleURI="http://www.cleanharbors.com/role/STOCKBASEDCOMPENSATIONAdditionalInformationDetails" xlink:type="simple" xlink:href="clh-20200930.xsd#STOCKBASEDCOMPENSATIONAdditionalInformationDetails"/>
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/STOCKBASEDCOMPENSATIONAdditionalInformationDetails" xlink:type="extended"/>
  <link:roleRef roleURI="http://www.cleanharbors.com/role/STOCKBASEDCOMPENSATIONRestrictedStockAwardsDetails" xlink:type="simple" xlink:href="clh-20200930.xsd#STOCKBASEDCOMPENSATIONRestrictedStockAwardsDetails"/>
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/STOCKBASEDCOMPENSATIONRestrictedStockAwardsDetails" xlink:type="extended"/>
  <link:roleRef roleURI="http://www.cleanharbors.com/role/STOCKBASEDCOMPENSATIONPerformanceStockAwardsDetails" xlink:type="simple" xlink:href="clh-20200930.xsd#STOCKBASEDCOMPENSATIONPerformanceStockAwardsDetails"/>
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/STOCKBASEDCOMPENSATIONPerformanceStockAwardsDetails" xlink:type="extended"/>
  <link:roleRef roleURI="http://www.cleanharbors.com/role/COMMITMENTSANDCONTINGENCIES" xlink:type="simple" xlink:href="clh-20200930.xsd#COMMITMENTSANDCONTINGENCIES"/>
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/COMMITMENTSANDCONTINGENCIES" xlink:type="extended"/>
  <link:roleRef roleURI="http://www.cleanharbors.com/role/COMMITMENTSANDCONTINGENCIESDetails" xlink:type="simple" xlink:href="clh-20200930.xsd#COMMITMENTSANDCONTINGENCIESDetails"/>
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/COMMITMENTSANDCONTINGENCIESDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_clh_SiteContingencyNumberOfSites_f934b3e3-6d8e-4908-9d3d-a84aea0f0a34" xlink:href="clh-20200930.xsd#clh_SiteContingencyNumberOfSites"/>
    <link:loc xlink:type="locator" xlink:label="loc_clh_SiteContingencyNumberOfSitesOwnedByEntity_74223387-7f03-4cb5-89df-335ff1be8b87" xlink:href="clh-20200930.xsd#clh_SiteContingencyNumberOfSitesOwnedByEntity"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_clh_SiteContingencyNumberOfSites_f934b3e3-6d8e-4908-9d3d-a84aea0f0a34" xlink:to="loc_clh_SiteContingencyNumberOfSitesOwnedByEntity_74223387-7f03-4cb5-89df-335ff1be8b87" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_clh_SiteContingencyNumberOfSitesOwnedByThirdParty_17fa405b-de33-4f65-a297-b668e8717a38" xlink:href="clh-20200930.xsd#clh_SiteContingencyNumberOfSitesOwnedByThirdParty"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_clh_SiteContingencyNumberOfSites_f934b3e3-6d8e-4908-9d3d-a84aea0f0a34" xlink:to="loc_clh_SiteContingencyNumberOfSitesOwnedByThirdParty_17fa405b-de33-4f65-a297-b668e8717a38" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_clh_SiteContingencyNumberOfSitesOwnedByThirdParty_02bf8749-404e-4d5e-bb27-2353eb3a8464" xlink:href="clh-20200930.xsd#clh_SiteContingencyNumberOfSitesOwnedByThirdParty"/>
    <link:loc xlink:type="locator" xlink:label="loc_clh_SiteContingencyEnvironmentalRemediationExpenseSettledNumberOfSitesOwnedByThirdParty_538baaf0-b18e-43ae-9302-0d0db074eaeb" xlink:href="clh-20200930.xsd#clh_SiteContingencyEnvironmentalRemediationExpenseSettledNumberOfSitesOwnedByThirdParty"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_clh_SiteContingencyNumberOfSitesOwnedByThirdParty_02bf8749-404e-4d5e-bb27-2353eb3a8464" xlink:to="loc_clh_SiteContingencyEnvironmentalRemediationExpenseSettledNumberOfSitesOwnedByThirdParty_538baaf0-b18e-43ae-9302-0d0db074eaeb" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_clh_SiteContingencyEnvironmentalRemediationExpenseNumberOfSitesOwnedByThirdParty_c3d876f4-b45a-46d4-b1e5-9bdfbb33041a" xlink:href="clh-20200930.xsd#clh_SiteContingencyEnvironmentalRemediationExpenseNumberOfSitesOwnedByThirdParty"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_clh_SiteContingencyNumberOfSitesOwnedByThirdParty_02bf8749-404e-4d5e-bb27-2353eb3a8464" xlink:to="loc_clh_SiteContingencyEnvironmentalRemediationExpenseNumberOfSitesOwnedByThirdParty_c3d876f4-b45a-46d4-b1e5-9bdfbb33041a" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_clh_SiteContingencyNotRequiringEnvironmentalRemediationExpenseNumberOfSitesOwnedByThirdParty_eabe936d-d53c-4242-8e27-909042c7fba8" xlink:href="clh-20200930.xsd#clh_SiteContingencyNotRequiringEnvironmentalRemediationExpenseNumberOfSitesOwnedByThirdParty"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_clh_SiteContingencyNumberOfSitesOwnedByThirdParty_02bf8749-404e-4d5e-bb27-2353eb3a8464" xlink:to="loc_clh_SiteContingencyNotRequiringEnvironmentalRemediationExpenseNumberOfSitesOwnedByThirdParty_eabe936d-d53c-4242-8e27-909042c7fba8" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.cleanharbors.com/role/SEGMENTREPORTING" xlink:type="simple" xlink:href="clh-20200930.xsd#SEGMENTREPORTING"/>
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/SEGMENTREPORTING" xlink:type="extended"/>
  <link:roleRef roleURI="http://www.cleanharbors.com/role/SEGMENTREPORTINGTables" xlink:type="simple" xlink:href="clh-20200930.xsd#SEGMENTREPORTINGTables"/>
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/SEGMENTREPORTINGTables" xlink:type="extended"/>
  <link:roleRef roleURI="http://www.cleanharbors.com/role/SEGMENTREPORTINGNarrativeDetails" xlink:type="simple" xlink:href="clh-20200930.xsd#SEGMENTREPORTINGNarrativeDetails"/>
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/SEGMENTREPORTINGNarrativeDetails" xlink:type="extended"/>
  <link:roleRef roleURI="http://www.cleanharbors.com/role/SEGMENTREPORTINGThirdPartyRevenuestoDirectRevenuesDetails" xlink:type="simple" xlink:href="clh-20200930.xsd#SEGMENTREPORTINGThirdPartyRevenuestoDirectRevenuesDetails"/>
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/SEGMENTREPORTINGThirdPartyRevenuestoDirectRevenuesDetails" xlink:type="extended"/>
  <link:roleRef roleURI="http://www.cleanharbors.com/role/SEGMENTREPORTINGAdjustedEBITDAInformationDetails" xlink:type="simple" xlink:href="clh-20200930.xsd#SEGMENTREPORTINGAdjustedEBITDAInformationDetails"/>
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/SEGMENTREPORTINGAdjustedEBITDAInformationDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingIncomeLoss_8c9cfd6a-4f2b-4393-9a03-5ce6da6d8113" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OperatingIncomeLoss"/>
    <link:loc xlink:type="locator" xlink:label="loc_clh_AccretionOfEnvironmentalLiabilities_facc9c37-b47a-41fc-8d5b-0746a1f49108" xlink:href="clh-20200930.xsd#clh_AccretionOfEnvironmentalLiabilities"/>
    <link:calculationArc order="1" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OperatingIncomeLoss_8c9cfd6a-4f2b-4393-9a03-5ce6da6d8113" xlink:to="loc_clh_AccretionOfEnvironmentalLiabilities_facc9c37-b47a-41fc-8d5b-0746a1f49108" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DepreciationDepletionAndAmortization_b5b42aa1-0684-4d13-9043-9afed46143d4" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DepreciationDepletionAndAmortization"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OperatingIncomeLoss_8c9cfd6a-4f2b-4393-9a03-5ce6da6d8113" xlink:to="loc_us-gaap_DepreciationDepletionAndAmortization_b5b42aa1-0684-4d13-9043-9afed46143d4" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_clh_IncomeLossFromContinuingOperationsBeforeInterestTaxDepreciationAndAmortizationNet_c858bca5-9fc8-4505-bd3d-c34ec33d45a0" xlink:href="clh-20200930.xsd#clh_IncomeLossFromContinuingOperationsBeforeInterestTaxDepreciationAndAmortizationNet"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OperatingIncomeLoss_8c9cfd6a-4f2b-4393-9a03-5ce6da6d8113" xlink:to="loc_clh_IncomeLossFromContinuingOperationsBeforeInterestTaxDepreciationAndAmortizationNet_c858bca5-9fc8-4505-bd3d-c34ec33d45a0" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.cleanharbors.com/role/SEGMENTREPORTINGAssetsbyReportableSegmentDetails" xlink:type="simple" xlink:href="clh-20200930.xsd#SEGMENTREPORTINGAssetsbyReportableSegmentDetails"/>
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/SEGMENTREPORTINGAssetsbyReportableSegmentDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IntangibleAssetsNetIncludingGoodwill_4c3ec5c7-38cf-4e21-b777-19b98090283f" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IntangibleAssetsNetIncludingGoodwill"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_Goodwill_ec208c79-f34d-4576-9e73-e2e06f2f9853" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_Goodwill"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IntangibleAssetsNetIncludingGoodwill_4c3ec5c7-38cf-4e21-b777-19b98090283f" xlink:to="loc_us-gaap_Goodwill_ec208c79-f34d-4576-9e73-e2e06f2f9853" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IntangibleAssetsNetExcludingGoodwill_c41db61f-e384-446d-878a-7771728ca189" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IntangibleAssetsNetExcludingGoodwill"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IntangibleAssetsNetIncludingGoodwill_4c3ec5c7-38cf-4e21-b777-19b98090283f" xlink:to="loc_us-gaap_IntangibleAssetsNetExcludingGoodwill_c41db61f-e384-446d-878a-7771728ca189" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.cleanharbors.com/role/SEGMENTREPORTINGTotalAssetsbyGeographicalAreaDetails" xlink:type="simple" xlink:href="clh-20200930.xsd#SEGMENTREPORTINGTotalAssetsbyGeographicalAreaDetails"/>
  <link:calculationLink xlink:role="http://www.cleanharbors.com/role/SEGMENTREPORTINGTotalAssetsbyGeographicalAreaDetails" xlink:type="extended"/>
</link:linkbase>
